Institutes, Centers and Programs
The Department of Pediatrics is one of 14 clinical departments in the Duke School of Medicine engaged in breakthrough science. Duke Pediatrics researchers work in collaboration at the following department-based institutes, research centers and programs.
Alice and Y.T. Chen Center for Genetics and Genomics
In April 2006, Myozyme (recombinant acid alpha-glucosidase) was approved by the FDA for use in patients with Pompe disease, representing the culmination of efforts by YT Chen, MD, PhD, and colleagues to develop a life-saving treatment for this deadly condition. With the goal of reproducing the bench-to-bedside approach that generated alglucosidase alfa and now offers hope for patients with Pompe disease, the Chens made a gift to the Department of Pediatrics to establish the Alice and YT Chen Pediatric Genetics and Genomics Research Center. This initiative focuses on single gene disorders amenable to treatment approaches such as enzyme replacement therapy, small molecule therapy, substrate therapy, gene therapy, and others. Priya Kishnani, MD, Chief of the Division of Medical Genetics and the lead investigator in the international clinical trials of Myozyme, serves as the Medical Director of the Center.
Children's Health & Discovery Initiative
For more than eight decades, the faculty and staff in the Department of Pediatrics at Duke University School of Medicine have conducted pioneering child health research, and expertly trained future pediatrician-scientists. Now, under the umbrella of the recently launched Children's Health & Discovery Initiative, these efforts will have an even bigger and broader impact. By bringing together pediatric physician-scientists and faculty experts from a variety of fields across the Duke campus, the new initiative will drive multidisciplinary research collaborations focused on improving children's health and identifying pediatric origins of disease.
Duke Center for Childhood Obesity (DCCOR)
The overall mission of the Duke Center for Childhood Obesity Research (DCCOR) is to advance effective and equitable obesity prevention and treatment by conducting innovative interdisciplinary research to achieve optimal health for all children. DCCOR conducts independent, groundbreaking research that seeks to change practice and policy to help children lead healthier lives.
Duke Pediatric Immunocompromised Host Program
The Duke Pediatric Immunocompromised Host Program (DPIHP) is a multi-disciplinary, integrated clinical and research program that functionally links the care and advancement of immunocompromised children at Duke. The DPIHP spans the Departments of Pediatrics and Surgery, purposefully integrating the medical and surgical approaches to the patient in the specialty areas of solid organ transplant (liver, intestine, kidney and heart), bone marrow transplant, oncology, immunology and rheumatology.
The Pediatric Transplant Program at Duke Children’s Hospital is led by world-renowned experts in pediatric transplant, delivering a multidisciplinary, integrated team approach to state-of-the-art care to address the full spectrum of transplant needs of patients and their families. Our pediatric transplant program is one of the largest in the country with more than 30 years of experience performing a wide range of transplants and providing personalized, patient-centered care to each child from evaluation through follow-up.
Jean and George Brumley, Jr. Neonatal Perinatal Research Institute (NPRI)
The Jean and George Brumley, Jr. Neonatal Perinatal Research Institute (NPRI), established in 1997, is dedicated to developmental biology and focuses its research on the serious health problems of newborns. Among the areas of active investigation are the mechanisms of brain, lung and cardiovascular injury and the cellular etiology of birth defects.
Duke University Institutes and Research Centers
Department of Pediatrics researchers also work in collaboration at the following university institutes and research centers. In addition, our investigators benefit from the services provided by the institution's numerous core research facilities, which provide researchers with sophisticated equipment, knowledgeable advisors, and experienced support staff to facilitate discovery.
- Duke Cancer Institute (DCI)
- Duke Clinical Research Institute (DCRI)
- Duke Global Health Institute (DGHI)
- Duke Human Vaccine Institute (DHVI)
- Duke Institute for Brain Sciences (DIBS)
- Duke Molecular Physiology Institute (DMPI)
- Duke Translational Medicine Institute (DTMI)
- Duke Translational Research Institute (DTRI)
- Regeneration Next
- Trent Center for Bioethics, Humanities and History of Medicine
- Brain Imaging and Analysis Center (BIAC)
- Center for Applied Genomics & Precision Medicine
- Center for HIV-AIDS Vaccine Immunology (CHAVI)
- Center for Human Disease Modeling
- Center for Hyperbaric Medicine and Environmental Physiology