The division has a strong commitment to advancing the translation of discoveries from bench-to-bedside, and training the next generation of physician scientists.
The Division of Pediatric Transplant and Cellular Therapy (PTCT) in the Duke Department of Pediatrics is an internationally-renowned transplant program. Established in 1990, we have performed more than 2,200 transplants in children and young adults with over 100 unique diagnoses for patients from all over the world. Our patients receive cutting-edge treatment for a variety of severe and life-threatening illnesses, including cancer, blood disorders, immune deficiencies, hemoglobinopathies and certain inherited metabolic diseases. We have fully dedicated inpatient and outpatient programs which provide the highest quality of care to our patients. Our hepa-filtered inpatient unit is one of the largest in the country and is specifically designed to provide the best possible environment of care for immunocompromised patients. Established in 1990 as one of the first dedicated pediatric transplant units, our focus has expanded with the unique needs of pediatric and young adult stem cell transplant, cellular therapy, gene therapy and high risk oncology patients in mind. We have the capacity to deliver treatments requiring 1:1 nursing care from a staff trained and competent in chemotherapy, immunotherapy and complicated treatment regimens. We are also dedicated to educate and train the next generation of multidisciplinary clinicians and research investigators to advance the field.
Our faculty and staff is comprised of board-certified transplant and immunotherapy experts, hematology-oncology and transplant and cellular therapy fellows, advanced practice nurses, nurse and non-nurse clinical/research coordinators, social workers, inpatient and outpatient registered nurses, pharmacists, psychologists, nutritionists, physical therapists, child life specialists, translators and family support program professionals. Our team also works closely with the full complement of Duke pediatric specialists to provide specialized care for patients who have additional medical problems or experience complications after transplantation.
Accreditation, Credentials and Affiliations
The Division of Pediatric Transplant and Cellular Therapy has been accredited by the Foundation for Accreditation of Cellular Therapy (FACT) since 2005 and has been a member of the National Marrow Donor Program since 1991. The program contributes data to the Center for International Blood and Marrow Transplant Research (CIMBTR) and has been a core center of the Blood and Marrow Transplant Clinical Trials Network (BMT CTN) since it was established in 2001. Duke Children’s Hospital, and specifically, the subspecialty of pediatric cancer has consistently been ranked as one of the nation’s best hospitals by US News & World Report.
The division offers a rich and creative research environment involving collaborations with experts in multiple disciplines at the national and international levels, including the Pediatric Transplantation and Cellular Therapy Network (PTCTN), Children’s Oncology Group (COG), Pediatric Acute Lung Injury and Sepsis Investigators (PALISI), Blood and Marrow Transplant Clinical Trials Network (BMT CTN), among other organizations. As a National Cancer Institute-designated Comprehensive Cancer Center and member of the National Comprehensive Cancer Network and the Leukodystrophy Care Network, we are dedicated to conducting ongoing research to improve patient outcomes.
The division is supported by the Duke Stem Cell Transplant Laboratory (FACT and CAP accredited and CLIA certified), the Carolinas Cord Blood Bank (an FDA licensed, FACT and CAP accredited public cord blood bank), and the Robertson GMP Cell Manufacturing Laboratory (FDA registered and FACT accredited). The division collaborates with the Marcus Center for Cellular Cures which conducts discovery, IND enabling, laboratory-based, and translational research in the fields of transplantation and cellular therapies and provides multiple opportunities for fellows to be exposed to and gain skills in all aspects of transplant and cellular therapies research.