Y.T. and Alice Chen Pediatric Genetics and Genomics Research Center is focused on advancing therapies for single-gene disorders in children.

The Chen Center’s goal is to be a leader for pediatric genetic and genomic research, transforming the lives of children with rare diseases through innovative therapies, multidisciplinary collaboration, and a commitment to precision medicine.

chen center team

Synergistic Approach 

Our collaborative and multidisciplinary model brings together clinicians and scientists with expertise in genetics, metabolism, hepatology, neurology, cardiology, and other disciplines involved in the care of individuals with rare genetic diseases to develop solutions that are both scientifically rigorous and centered on patient needs. 

Meet The Chen Center Team

chen center research

Breakthrough Science

The Chen Center’s cutting-edge genomic science is directly linked to transformative therapies such as gene therapy and gene editing, with a strong emphasis on translating discovery into cures.

Learn About Chen Center Research

chen center impact

Revolutionary Impact

Our research outcomes are groundbreaking and directly meaningful to children and their families. At Duke, families receive world-class care supported by the latest genomic discoveries.

See Key Publications 

chen center global innovators

Global Innovators

With Duke’s global network as a foundation, the Chen Center also extends its reach beyond the U.S. to build international collaborations that advance diagnosis and care for underserved populations worldwide.

View Our Scientific Advisory Board 

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About the Center 

Founded through the generosity of Y.T. and Alice Chen in 2006, the Chen Center is dedicated to advancing the frontiers of knowledge and care in pediatric genetics and genomics. Our work is made possible through proceeds and royalties from previous discoveries, federal, industry, and foundation grants, as well as the generosity of grateful patients, families, and other philanthropic supporters. 

Learn About Our Mission & Objectives

 

Nationally Recognized for Improving the Lives of Children with Rare Genetic Conditions 

The Chen Center is a designated Rare Disease Center of Excellence by the National Organization for Rare Disorders (NORD®).