Published Studies
How you can help
Our mission is to provide the professional infrastructure and clinical expertise directed toward improving the quality of care and long-term outcomes for our babies. Find out how you can help support our babies and our research.
Publications
The following publications from 2017-2018 highlight clinical studies completed at the Duke Neonatal Perinatal Research Unit.
Pulmonary
- Caffeine use and risk of failure of initial continuous positive airway pressure in preterm infants
- Determining late respiratory disease in preterm infants
- Dexamethasone use in preterm infants
- Lung development in preterm infants
- Novel genes and associated pathways in determining respiratory outcomes in preterm births
- Outcomes and growth status in the SUPPORT Trial Cohort of preterm infants
- Respiratory outcomes at 1 year of age in preterm infants
- Use of Indomethacin in preterm infants and the risk for bronchopulmonary dysplasia
- Use of diuretics in preterm infants
Cardiovascular
- Atrial septal defects and bronchopulmonary dysplasia in premature infants
- Furosemide exposure and Patent Ductus Arteriosus in preterm infants
- Respiratory care during hospitalization for preterm infants
Neurology
- Early lumbar puncture and risk of intraventricular hemorrhage in preterm infants
- Long term outcomes for preterm infants
- Outcomes of delayed whole body cooling for infants born with hypoxic-ischemic encephalopathy
- Outcomes of depth and duration of whole body cooling for infants born with hypoxic-ischemic encephalopathy
- Outcomes of whole body cooling for infants born with hypoxic-ischemic
- Outcome of preterm infants with transient cystic periventricular leukomalacia
Infection
- Genome-wide association of sepsis in extremely premature infants
- Systematic review and meta-analysis: Gene association studies in neonatal sepsis
- Antifungal susceptibility and clinical outcome in neonatal candidiasis
- Risk factors for Group B streptococcal disease in neonates
- Timing of multi-organ dysfunction among infants with fatal fulminant sepsis
- Dosing antibiotics in neonates: review of the pharmacokinetic data
- Safety of high-dose acyclovir in infants with suspected and confirmed neonatal herpes simplex virus
- Identification of extremely premature infants at low risk for early-onset sepsis
- Late-onset sepsis in extremely premature infants
- Genome-wide association study of sepsis in extremely premature infants
- Systematic review and meta-analysis: Gene association studies in neonatal sepsis
- Safety, effectiveness, and exposure-response of micafungin in infants
- Enterocolitis incidence and outcomes in very low birth weight infants
- Micafungin versus Amphotericin B Deoxycholate in infants with invasive candidiasis
- Exposure-response analysis of micafungin in neonatal candidiasis: Pooled analysis of two clinical trials
- Antifungal susceptibility and clinical outcome in neonatal candidiasis
Gastrointestinal
Ophthalmology
- Effects of inositol on retinopathy of prematurity in preterm infants
- Handheld spectral domain optical coherence tomography imaging through the undilated pupil in infants born with hypoxic injury or hydrocephalus
Ethics/Palliative Care
Management of Complex Issues
- Definition of gentle ventilation in congenital diaphragmatic hernia: A survey of neonatologists and pediatric surgeons
- Delivery room resuscitation in moderately preterm infants
- Neonatal outcomes of moderately preterm infants compared to extremely preterm infants
- Safety of enalapril in infants admitted to the neonatal intensive care unit
- Admission temperature and associated mortality and morbidity among moderately and extremely preterm infants
- A case of infant delirium in the neonatal intensive care unit
- Association of in utero magnesium exposure and spontaneous intestinal perforations in extremely low birth weight infants
- National survey of neonatal intensive care unit medication safety practices
- Prevalence and safety of diazoxide in the neonatal intensive care unit
- Morphine vs methadone treatment for infants with neonatal abstinence syndrome
- Prolonged furosemide exposure and risk of abnormal newborn hearing screen in premature infants
- Directory for neonatal intensive care
- Leveraging big data to inform pediatric development programs
- Sildenafil exposure in the neonatal intensive care unit
- Evaluation of gentamicin-induced ototoxicity in hospitalized infants
- Weaning of moderately preterm infants from the incubator to the crib
- Surgical necrotizing enterocolitis in extremely premature neonates
- Admission temperature and associated mortality and morbidity among moderately and extremely preterm infants
Long-term Outcomes
- An anthropometric survey of US pre-term and full-term neonates
- A weight estimation strategy for preterm and full-term infants
- Barriers to enrollment in a randomized controlled trial of hydrocortisone for cardiovascular insufficiency in term and late preterm newborn infants
- Use of midliner positioning system for prevention of dolichocephaly in preterm infants
- Extreme preterm infant rates of overweight and obesity at school age in the SUPPORT cohort
- Survival and neurodevelopmental outcomes among periviable infants
- Dolicocephaly in preterm infants: prevalence, risk factors, and early motor outcomes
How you can participate
If you currently have a baby in the Duke Intensive Care Nursery, and you think you may want to participate in any of our research studies, please ask your baby’s nurse or doctor to contact us. The NPRU team will then contact you to explain the criteria for study eligibility and describe the potential benefits and risks for entering the study.
Riley Ashley
NPRU Graduate
Learn more
To learn more about the Duke Intensive Care Nursery, visit the Duke Division of Neonatology website. For more information about the Neonatal Perinatal Research Unit or to learn more about our clinical trials, email us at npru@duke.edu, or call 919-681-4913.