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Neonatal-Perinatal Research Unit


Dedicated to improving the outcomes of our babies

The Neonatal Perinatal Research Unit (NPRU) explores causes, preventative measures, and treatments for many of the major negative health outcomes that impact premature and full-term infants. Our research is focused on both improving the care that we provide to these newborns and continuing to explore new therapies and treatment options.

How you can help

Our mission is to provide the professional infrastructure and clinical expertise directed toward improving the quality of care and long-term outcomes for our babies. Find out how you can help support our babies and our research.

Support Neonatal Research

Research Funding

Duke is currently using cord blood for infants born with signs of brain injury caused by lack of adequate blood flow and oxygen delivery. Over the past 20 years, Duke researchers have worked to understand the special biologic restorative properties of progenitor and stem cells collected from umbilical cord blood. We are proud to be the recipient of a grant from the Robertson Foundation. This grant is funding our phase II randomized placebo-controlled trial of cells for neonatal brain injury at 11 additional centers across the country. Duke has also received supplemental funding from the New York Cerebral Palsy Alliance Research Foundation, Inc. to further support this important project.

In the spring of 2017 Eunice Kennedy Shriver National Institute of Child Health and Human Development, Neonatal Research Network, an institute of the National Institutes of Health (NIH), awarded Duke University our fourth consecutive competitive renewal for the Neonatal Research Network. The mission of the NRN is to conduct clinical trials and observational studies in neonatal medicine in order to reduce morbidity and mortality and promote healthy outcomes for our babies. We are proud to be a member of this prestigious organization.

The following are the primary sources of research funding for the Neonatal Perinatal Research Unit (NPRU):

How you can participate

If you currently have a baby in the Duke Intensive Care Nursery, and you think you may want to participate in any of our research studies, please ask your baby’s nurse or doctor to contact us. The NPRU team will then contact you to explain the criteria for study eligibility and describe the potential benefits and risks for entering the study. Learn about our current research opportunities.

We believe that a significant part of doing our best for babies in the intensive care unit is working hard to identify the best, safest and most effective ways to provide care. To do this, Duke is proud to participate in multiple research studies.

C. Michael Cotten, MD, MHS, Chief of the Division of Neonatology

Learn more

To learn more about the Duke Intensive Care Nursery, visit the Duke Division of Neonatology website. For more information about the Neonatal Perinatal Research Unit or to learn more about our clinical trials, email us at, or call 919-681-4913.