Human Avatars Help Make Gene Therapy More Effective

Karl-Dimiter Bissig, MD, PhD, and team developed a new experimental humanized animal model that mimics human responses better than previous models. This new technology could help improve the efficiency of clinical trials for a wide range of drug treatments and diseases.

Finding a path through the land of the undiagnosed

As many as 30 million Americans live with a rare or undiagnosed disease. Many spend years seeing doctors, undergoing tests, and scouring the internet in a desperate search for answers. Vandana Shashi, MD, professor of pediatrics in the Division of Medical Genetics, and the Undiagnosed Diseases Network (UDN) clinical site at Duke give these patients a new avenue of hope.

My View: Debbie Antonelli

Debbie Antonelli discusses how her son Frankie's experience at the Duke Down Syndrome Clinic prepared him for college success through the Clemson LIFE program.

Genetic Counselor Awareness Day

November 4, 2021 recognizes Genetic Counselor Awareness Day, sponsored by the National Society of Genetic Counselors (

$8M grant aims to better understand disease mechanisms of schizophrenia

A new $8 million NIH grant seeks to uncover more clues into what genes increase the risk of developing schizophrenia. Greg Crawford, Charles Gersbach, Timothy Reddy, and Raluca Gord├ón at Duke have teamed up with researchers from UNC Chapel Hill and Yale University to narrow down areas of the genome previously marked relevant to schizophrenia risk.