Skip to main content

Search form

You are here

Michael Cohen-Wolkowiez, MD, PhD

Professor of Pediatrics
Member in the Duke Clinical Research Institute
Campus mail: 300 West Morgan Street, Box 3850, Durham, NC 27701
Phone: (919) 668-8812
Email address: michael.cohenwolkowiez@duke.edu

Pharmacokinetics and Pharmacodynamics of drugs in children with an emphasis in anti-infective products.

Education and Training

  • Pediatric Infectious Diseases Fellowship, Pediatrics, Duke University, 2006 - 2009
  • Pediatric Chief Resident, Pediatrics, University of Miami, 2005 - 2006
  • Pediatric Residency, Pediatrics, University of Miami, 2002 - 2005
  • Ph.D., University of North Carolina at Chapel Hill School of Medicine, 2012
  • M.D., Universidad Central De Venezuela (Venezuela), 2001

Selected Grants and Awards

Publications

Noveck, RJ, Guptill, JT, Cohen-Wolkowiez, M, Hauser, BM, and Suffredini, AF. "DOSE-RELATED INFLAMMATORY EFFECTS OF INTRAVENOUS ENDOTOXIN IN HUMANS: EVALUATION OF A NEW CLINICAL LOT (CCRE LOT 94332B1) OF ESCHERICHIA COLIO: 113 ENDOTOXIN (LPS)." March 2018.

Scholars@Duke

Gerhart, JG, Watt, KM, Edginton, A, Wade, KC, Jr, BDK, Smith, PB, Hornik, CP, Cohen-Wolkowiez, M, Duara, S, Ross, AS, Shattuck, K, Stewart, DL, Neu, N, and Gonzalez, D. "PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING OF FLUCONAZOLE USING PLASMA AND CEREBROSPINAL FLUID SAMPLES COLLECTED FROM PRETERM AND TERM INFANTS." March 2018.

Scholars@Duke

Dallefeld, SH, Atz, AM, Yogev, R, Sullivan, JE, Al-Uzri, A, Mendley, SR, Laughon, M, Hornik, CP, Melloni, C, Harper, B, Lewandowski, A, Mitchell, J, Wu, H, Green, TP, and Cohen-Wolkowiez, M. "A pharmacokinetic model for amiodarone in infants developed from an opportunistic sampling trial and published literature data." Journal of pharmacokinetics and pharmacodynamics (February 12, 2018).

Full Text

Le, J, Poindexter, B, Sullivan, JE, Laughon, M, Delmore, P, Blackford, M, Yogev, R, James, LP, Melloni, C, Harper, B, Mitchell, J, Benjamin, DK, Boakye-Agyeman, F, and Cohen-Wolkowiez, M. "Comparative Analysis of Ampicillin Plasma and Dried Blood Spot Pharmacokinetics in Neonates." Therapeutic drug monitoring 40, no. 1 (February 2018): 103-108.

Full Text

Autmizguine, J, Tan, S, Cohen-Wolkowiez, M, Cotten, CM, Wiederhold, N, Goldberg, RN, Adams-Chapman, I, Stoll, BJ, Smith, PB, Benjamin, DK, and NICHD Neonatal Research Network, . "Antifungal Susceptibility and Clinical Outcome in Neonatal Candidiasis." The Pediatric infectious disease journal (January 24, 2018).

Full Text

Hornik, CP, Onufrak, NJ, Smith, PB, Cohen-Wolkowiez, M, Laughon, MM, Clark, RH, and Gonzalez, D. "Association between oral sildenafil dosing, predicted exposure, and systemic hypotension in hospitalised infants." Cardiology in the young 28, no. 1 (January 2018): 85-92.

Full Text

Autmizguine, J, Melloni, C, Hornik, CP, Dallefeld, S, Harper, B, Yogev, R, Sullivan, JE, Atz, AM, Al-Uzri, A, Mendley, S, Poindexter, B, Mitchell, J, Lewandowski, A, Delmore, P, Cohen-Wolkowiez, M, Gonzalez, D, and the Pediatric Trials Network Steering Committee, . "Population Pharmacokinetics of Trimethoprim-Sulfamethoxazole in Infants and Children." Antimicrobial agents and chemotherapy 62, no. 1 (January 2018).

Full Text

Salerno, SN, Edginton, A, Cohen-Wolkowiez, M, Hornik, CP, Watt, KM, Jamieson, BD, and Gonzalez, D. "Development of an Adult Physiologically Based Pharmacokinetic Model of Solithromycin in Plasma and Epithelial Lining Fluid." CPT: pharmacometrics & systems pharmacology 6, no. 12 (December 2017): 814-822.

Full Text

Hwang, MF, Beechinor, RJ, Wade, KC, Benjamin, DK, Smith, PB, Hornik, CP, Capparelli, EV, Duara, S, Kennedy, KA, Cohen-Wolkowiez, M, and Gonzalez, D. "External Evaluation of Two Fluconazole Infant Population Pharmacokinetic Models." Antimicrobial agents and chemotherapy 61, no. 12 (December 2017).

Full Text

Hornik, CP, Wu, H, Edginton, AN, Watt, K, Cohen-Wolkowiez, M, and Gonzalez, D. "Development of a Pediatric Physiologically-Based Pharmacokinetic Model of Clindamycin Using Opportunistic Pharmacokinetic Data." Clinical pharmacokinetics 56, no. 11 (November 2017): 1343-1353.

Full Text

Pages