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Michael Cohen-Wolkowiez, MD, PhD

Professor of Pediatrics
Member in the Duke Clinical Research Institute
Campus mail: 300 West Morgan Street, Box 3850, Durham, NC 27701
Phone: (919) 668-8812
Email address: michael.cohenwolkowiez@duke.edu

Pharmacokinetics and Pharmacodynamics of drugs in children with an emphasis in anti-infective products.

Education and Training

  • Pediatric Infectious Diseases Fellowship, Pediatrics, Duke University, 2006 - 2009
  • Pediatric Chief Resident, Pediatrics, University of Miami, 2005 - 2006
  • Pediatric Residency, Pediatrics, University of Miami, 2002 - 2005
  • Ph.D., University of North Carolina at Chapel Hill School of Medicine, 2012
  • M.D., Universidad Central De Venezuela (Venezuela), 2001

Selected Grants and Awards

Publications

Balevic, SJ, Smith, PB, Testoni, D, Wu, H, Brouwer, KLR, Zimmerman, KO, Rivera-Chaparro, ND, Benjamin, DK, and Cohen-Wolkowiez, M. "Cefazolin pharmacokinetics in premature infants." Journal of Perinatology : Official Journal of the California Perinatal Association (April 3, 2019).

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Balevic, SJ, Green, TP, Clowse, MEB, Eudy, AM, Schanberg, LE, and Cohen-Wolkowiez, M. "Pharmacokinetics of Hydroxychloroquine in Pregnancies with Rheumatic Diseases." Clinical Pharmacokinetics 58, no. 4 (April 2019): 525-533.

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Smith, PB, Cotten, CM, Hudak, ML, Sullivan, JE, Poindexter, BB, Cohen-Wolkowiez, M, Boakye-Agyeman, F, Lewandowski, A, Anand, R, Benjamin, DK, Laughon, MM, and Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee, . "Rifampin Pharmacokinetics and Safety in Preterm and Term Infants." Antimicrobial Agents and Chemotherapy (March 25, 2019).

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Thompson, EJ, Wu, H, Maharaj, A, Edginton, AN, Balevic, SJ, Cobbaert, M, Cunningham, AP, Hornik, CP, and Cohen-Wolkowiez, M. "Physiologically Based Pharmacokinetic Modeling for Trimethoprim and Sulfamethoxazole in Children." Clinical Pharmacokinetics (March 6, 2019).

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Drolet, BA, Boakye-Agyeman, F, Harper, B, Holland, K, Lewandowski, A, Stefanko, N, Melloni, C, and Pediatric Trials Network Steering Committee, . "Systemic Timolol Exposure Following Topical Application to Infantile Hemangiomas." Journal of the American Academy of Dermatology (February 18, 2019).

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Watt, KM, Hornik, CP, Balevic, SJ, Mundakel, G, Cotten, CM, Harper, B, Benjamin, DK, Anand, R, Laughon, M, Smith, PB, Cohen-Wolkowiez, M, and Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee, . "Pharmacokinetics of ticarcillin-clavulanate in premature infants." British Journal of Clinical Pharmacology (February 2, 2019).

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Rivera-Chaparro, ND, Ericson, J, Wu, H, Smith, PB, Clark, RH, Benjamin, DK, Cohen-Wolkowiez, M, and Greenberg, RG. "Safety, Effectiveness and Exposure-response of Micafungin in Infants: Application of an Established Pharmacokinetics Model to Electronic Health Records." The Pediatric Infectious Disease Journal 38, no. 2 (February 2019): e26-e28.

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Cohen-Wolkowiez, M, and Benjamin, DK. "Development of Therapeutics for Children-A Tricky Balancing Act." Jama Pediatrics 173, no. 1 (January 2019): 18-19.

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Balevic, SJ, Cohen-Wolkowiez, M, Eudy, AM, Green, TP, Schanberg, LE, and Clowse, MEB. "Hydroxychloroquine Levels throughout Pregnancies Complicated by Rheumatic Disease: Implications for Maternal and Neonatal Outcomes." The Journal of Rheumatology 46, no. 1 (January 2019): 57-63.

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Ku, LC, Hornik, CP, Beechinor, RJ, Chamberlain, JM, Guptill, JT, Harper, B, Capparelli, EV, Martz, K, Anand, R, Cohen-Wolkowiez, M, Gonzalez, D, and Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee, . "Population Pharmacokinetics and Exploratory Exposure-Response Relationships of Diazepam in Children Treated for Status Epilepticus." Cpt: Pharmacometrics & Systems Pharmacology 7, no. 11 (November 2018): 718-727.

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