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Michael Cohen-Wolkowiez, MD, PhD

Professor of Pediatrics
Member in the Duke Clinical Research Institute
Campus mail: 300 West Morgan Street, Box 3850, Durham, NC 27701
Phone: (919) 668-8812
Email address: michael.cohenwolkowiez@duke.edu

Pharmacokinetics and Pharmacodynamics of drugs in children with an emphasis in anti-infective products.

Education and Training

  • Pediatric Infectious Diseases Fellowship, Pediatrics, Duke University, 2006 - 2009
  • Pediatric Chief Resident, Pediatrics, University of Miami, 2005 - 2006
  • Pediatric Residency, Pediatrics, University of Miami, 2002 - 2005
  • Ph.D., University of North Carolina at Chapel Hill School of Medicine, 2012
  • M.D., Universidad Central De Venezuela (Venezuela), 2001

Selected Grants and Awards

Publications

Hornik, CP, Onufrak, NJ, Smith, PB, Cohen-Wolkowiez, M, Laughon, MM, Clark, RH, and Gonzalez, D. "Association between oral sildenafil dosing, predicted exposure, and systemic hypotension in hospitalised infants." Cardiology in the young 28, no. 1 (January 2018): 85-92.

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Autmizguine, J, Melloni, C, Hornik, CP, Dallefeld, S, Harper, B, Yogev, R, Sullivan, JE, Atz, AM, Al-Uzri, A, Mendley, S, Poindexter, B, Mitchell, J, Lewandowski, A, Delmore, P, Cohen-Wolkowiez, M, Gonzalez, D, and the Pediatric Trials Network Steering Committee, . "Population Pharmacokinetics of Trimethoprim-Sulfamethoxazole in Infants and Children." Antimicrobial agents and chemotherapy 62, no. 1 (January 2018).

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Salerno, SN, Edginton, A, Cohen-Wolkowiez, M, Hornik, CP, Watt, KM, Jamieson, BD, and Gonzalez, D. "Development of an Adult Physiologically Based Pharmacokinetic Model of Solithromycin in Plasma and Epithelial Lining Fluid." December 2017.

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Hwang, MF, Beechinor, RJ, Wade, KC, Benjamin, DK, Smith, PB, Hornik, CP, Capparelli, EV, Duara, S, Kennedy, KA, Cohen-Wolkowiez, M, and Gonzalez, D. "External Evaluation of Two Fluconazole Infant Population Pharmacokinetic Models." Antimicrobial agents and chemotherapy 61, no. 12 (December 2017).

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Hornik, CP, Wu, H, Edginton, AN, Watt, K, Cohen-Wolkowiez, M, and Gonzalez, D. "Development of a Pediatric Physiologically-Based Pharmacokinetic Model of Clindamycin Using Opportunistic Pharmacokinetic Data." Clinical pharmacokinetics 56, no. 11 (November 2017): 1343-1353.

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Balevic, SJ, Becker, ML, Cohen-Wolkowiez, M, and Schanberg, LE. "Clinical Trial Design in Juvenile Idiopathic Arthritis." Paediatric drugs 19, no. 5 (October 2017): 379-389.

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Watt, KM, Cohen-Wolkowiez, M, Williams, DC, Bonadonna, DK, Cheifetz, IM, Thakker, D, Benjamin, DK, and Brouwer, KLR. "Antifungal Extraction by the Extracorporeal Membrane Oxygenation Circuit." The journal of extra-corporeal technology 49, no. 3 (September 2017): 150-159.

Scholars@Duke

Rivera-Chaparro, ND, Cohen-Wolkowiez, M, and Greenberg, RG. "Dosing antibiotics in neonates: review of the pharmacokinetic data." Future microbiology 12 (September 2017): 1001-1016.

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Greenberg, RG, Wu, H, Laughon, M, Capparelli, E, Rowe, S, Zimmerman, KO, Smith, PB, and Cohen-Wolkowiez, M. "Population Pharmacokinetics of Dexmedetomidine in Infants." Journal of clinical pharmacology 57, no. 9 (September 2017): 1174-1182.

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Thakkar, N, Guptill, JT, Aleš, K, Jacobus, D, Jacobus, L, Peloquin, C, Cohen-Wolkowiez, M, Gonzalez, D, and DAPPER Study Group, . "Population Pharmacokinetics/Pharmacodynamics of 3,4-Diaminopyridine Free Base in Patients With Lambert-Eaton Myasthenia." September 2017.

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