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Michael Cohen-Wolkowiez, MD, PhD

Professor of Pediatrics
Member in the Duke Clinical Research Institute
Campus mail: 300 West Morgan Street, Box 3850, Durham, NC 27701
Phone: (919) 668-8812
Email address: michael.cohenwolkowiez@duke.edu

Pharmacokinetics and Pharmacodynamics of drugs in children with an emphasis in anti-infective products.

Education and Training

  • Pediatric Infectious Diseases Fellowship, Pediatrics, Duke University, 2006 - 2009
  • Pediatric Chief Resident, Pediatrics, University of Miami, 2005 - 2006
  • Pediatric Residency, Pediatrics, University of Miami, 2002 - 2005
  • Ph.D., University of North Carolina at Chapel Hill School of Medicine, 2012
  • M.D., Universidad Central De Venezuela (Venezuela), 2001

Selected Grants and Awards

Publications

Thompson, Elizabeth J., Huali Wu, Anil Maharaj, Andrea N. Edginton, Stephen J. Balevic, Marjan Cobbaert, Anthony P. Cunningham, Christoph P. Hornik, and Michael Cohen-Wolkowiez. “Physiologically Based Pharmacokinetic Modeling for Trimethoprim and Sulfamethoxazole in Children..” Clin Pharmacokinet 58, no. 7 (July 2019): 887–98. https://doi.org/10.1007/s40262-018-00733-1.

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Maharaj, Anil R., Huali Wu, Christoph P. Hornik, and Michael Cohen-Wolkowiez. “Pitfalls of using numerical predictive checks for population physiologically-based pharmacokinetic model evaluation..” J Pharmacokinet Pharmacodyn 46, no. 3 (June 2019): 263–72. https://doi.org/10.1007/s10928-019-09636-5.

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Smith, P Brian, C Michael Cotten, Mark L. Hudak, Janice E. Sullivan, Brenda B. Poindexter, Michael Cohen-Wolkowiez, Felix Boakye-Agyeman, et al. “Rifampin Pharmacokinetics and Safety in Preterm and Term Infants..” Antimicrob Agents Chemother 63, no. 6 (June 2019). https://doi.org/10.1128/AAC.00284-19.

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Gerhart, Jacqueline G., Kevin M. Watt, Andrea Edginton, Kelly C. Wade, Sara N. Salerno, Daniel K. Benjamin, P Brian Smith, et al. “Physiologically-Based Pharmacokinetic Modeling of Fluconazole Using Plasma and Cerebrospinal Fluid Samples From Preterm and Term Infants..” In Cpt Pharmacometrics Syst Pharmacol, 2019. https://doi.org/10.1002/psp4.12414.

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Watt, Kevin M., Christoph P. Hornik, Stephen J. Balevic, Gratias Mundakel, C Michael Cotten, Barrie Harper, Daniel K. Benjamin, et al. “Pharmacokinetics of ticarcillin-clavulanate in premature infants..” Br J Clin Pharmacol 85, no. 5 (May 2019): 1021–27. https://doi.org/10.1111/bcp.13882.

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Balevic, Stephen J., P Brian Smith, Daniela Testoni, Huali Wu, Kim L. R. Brouwer, Kanecia O. Zimmerman, Nazario D. Rivera-Chaparro, Daniel K. Benjamin, and Michael Cohen-Wolkowiez. “Cefazolin pharmacokinetics in premature infants..” J Perinatol, April 3, 2019. https://doi.org/10.1038/s41372-019-0368-z.

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Balevic, Stephen J., Thomas P. Green, Megan E. B. Clowse, Amanda M. Eudy, Laura E. Schanberg, and Michael Cohen-Wolkowiez. “Pharmacokinetics of Hydroxychloroquine in Pregnancies with Rheumatic Diseases..” Clin Pharmacokinet 58, no. 4 (April 2019): 525–33. https://doi.org/10.1007/s40262-018-0712-z.

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Drolet, Beth A., Felix Boakye-Agyeman, Barrie Harper, Kristen Holland, Andrew Lewandowski, Nicole Stefanko, Chiara Melloni, and Chiara Pediatric Trials Network Steering Committee. “Systemic Timolol Exposure Following Topical Application to Infantile Hemangiomas..” J Am Acad Dermatol, February 18, 2019. https://doi.org/10.1016/j.jaad.2019.02.029.

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Rivera-Chaparro, Nazario D., Jessica Ericson, Huali Wu, P Brian Smith, Reese H. Clark, Daniel K. Benjamin, Michael Cohen-Wolkowiez, and Rachel G. Greenberg. “Safety, Effectiveness and Exposure-response of Micafungin in Infants: Application of an Established Pharmacokinetics Model to Electronic Health Records..” Pediatr Infect Dis J 38, no. 2 (February 2019): e26–28. https://doi.org/10.1097/INF.0000000000002045.

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Cohen-Wolkowiez, Michael, and Daniel K. Benjamin. “Development of Therapeutics for Children-A Tricky Balancing Act..” Jama Pediatr 173, no. 1 (January 1, 2019): 18–19. https://doi.org/10.1001/jamapediatrics.2018.4026.

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