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Michael Anthony Moody, MD

Associate Professor of Pediatrics
Associate Professor in the Department of Immunology
Member of the Duke Human Vaccine Institute
Campus mail: 2 Genome Ct, MSRB II Room 3007, Durham, NC 27710
Phone: (919) 668-2551
Email address: tony.moody@duke.edu

Tony Moody, MD is an Associate Professor in the Department of Pediatrics, Division of Infectious Diseases and the Department of Immunology at Duke University Medical Center. Dr. Moody is the Director of the Laboratory of B cell Immunotechnology at the Duke Human Vaccine Institute (DHVI). Research in the Moody lab is focused on understanding the B cell responses during the earliest stages of HIV infection. The lab has become a resource for human phenotyping, flow characterization, staining and analysis at DHVI.  Dr. Moody is also the Director of the CHAVI DHVI Repository that provides support for the collaborative work occurring at DHVI and with its many collaborators around the world by providing processing, shipping, and inventory support for a wide array of projects. Additionally, Dr. Moody serves as one of the Principal Investigators of the new Duke Collaborative Influenza Vaccine Innovation Centers (CIVICs) where he will conduct basic immunology and virology research to identify potential influenza vaccine candidates.

In addition, the Moody lab has active projects looking at the response to HIV-1, syphilis, and autoimmunity.

Education and Training

  • Fellowship, Pediatric Infectious Diseases, Pediatrics, Duke University, 2003 - 2006
  • Pediatric Chief Resident, Pediatrics, Emory University, 2002 - 2003
  • Pediatric Internship & Residency, Pediatrics, Emory University, 1999 - 2002
  • M.D., Duke University, 1999

Selected Grants and Awards

Publications

Kepler, Thomas B., Hua-Xin Liao, S Munir Alam, Rekha Bhaskarabhatla, Ruijun Zhang, Chandri Yandava, Shelley Stewart, et al. “Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies.” Cell Host Microbe 16, no. 3 (September 10, 2014): 304–13. https://doi.org/10.1016/j.chom.2014.08.006.

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Trama, Ashley M., M Anthony Moody, S Munir Alam, Frederick H. Jaeger, Bradley Lockwood, Robert Parks, Krissey E. Lloyd, et al. “HIV-1 envelope gp41 antibodies can originate from terminal ileum B cells that share cross-reactivity with commensal bacteria.” Cell Host Microbe 16, no. 2 (August 13, 2014): 215–26. https://doi.org/10.1016/j.chom.2014.07.003.

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Gao, Feng, Mattia Bonsignori, Hua-Xin Liao, Amit Kumar, Shi-Mao Xia, Xiaozhi Lu, Fangping Cai, et al. “Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies.” Cell 158, no. 3 (July 31, 2014): 481–91. https://doi.org/10.1016/j.cell.2014.06.022.

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Jackson, Katherine J. L., Yi Liu, Krishna M. Roskin, Jacob Glanville, Ramona A. Hoh, Katie Seo, Eleanor L. Marshall, et al. “Human responses to influenza vaccination show seroconversion signatures and convergent antibody rearrangements.” Cell Host Microbe 16, no. 1 (July 9, 2014): 105–14. https://doi.org/10.1016/j.chom.2014.05.013.

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Pollara, Justin, Mattia Bonsignori, M Anthony Moody, Pinghuang Liu, S Munir Alam, Kwan-Ki Hwang, Thaddeus C. Gurley, et al. “HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities.” J Virol 88, no. 14 (July 2014): 7715–26. https://doi.org/10.1128/JVI.00156-14.

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Garcia, Ambrosia, Sarah Keinonen, Ana M. Sanchez, Guido Ferrari, Thomas N. Denny, and M Anthony Moody. “Leukopak PBMC sample processing for preparing quality control material to support proficiency testing programs.” J Immunol Methods 409 (July 2014): 99–106. https://doi.org/10.1016/j.jim.2014.05.019.

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Haynes, Barton F., M Anthony Moody, Munir Alam, Mattia Bonsignori, Laurent Verkoczy, Guido Ferrari, Feng Gao, Georgia D. Tomaras, Hua-Xin Liao, and Garnett Kelsoe. “Progress in HIV-1 vaccine development.” J Allergy Clin Immunol 134, no. 1 (July 2014): 3–10. https://doi.org/10.1016/j.jaci.2014.04.025.

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Madani, Navid, Amy M. Princiotto, Arne Schön, Judith LaLonde, Yu Feng, Ernesto Freire, Jongwoo Park, et al. “CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies.” J Virol 88, no. 12 (June 2014): 6542–55. https://doi.org/10.1128/JVI.00540-14.

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Liu, Pinghuang, Latonya D. Williams, Xiaoying Shen, Mattia Bonsignori, Nathan A. Vandergrift, R Glenn Overman, M Anthony Moody, et al. “Capacity for infectious HIV-1 virion capture differs by envelope antibody specificity.” J Virol 88, no. 9 (May 2014): 5165–70. https://doi.org/10.1128/JVI.03765-13.

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Moody, M Anthony. “Modulation of HIV-1 immunity by adjuvants.” Curr Opin Hiv Aids 9, no. 3 (May 2014): 242–49. https://doi.org/10.1097/COH.0000000000000052.

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