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Michael Anthony Moody, MD

Associate Professor of Pediatrics
Associate Professor in the Department of Immunology
Member of the Duke Human Vaccine Institute
Campus mail: 2 Genome Ct, MSRB II Room 3007, Durham, NC 27710
Phone: (919) 668-2551
Email address: tony.moody@duke.edu

Tony Moody, MD is an Associate Professor in the Department of Pediatrics, Division of Infectious Diseases and the Department of Immunology at Duke University Medical Center. Dr. Moody is the Director of the Laboratory of B cell Immunotechnology at the Duke Human Vaccine Institute (DHVI). Research in the Moody lab is focused on understanding the B cell responses during the earliest stages of HIV infection. The lab has become a resource for human phenotyping, flow characterization, staining and analysis at DHVI.  Dr. Moody is also the Director of the CHAVI DHVI Repository that provides support for the collaborative work occurring at DHVI and with its many collaborators around the world by providing processing, shipping, and inventory support for a wide array of projects. Additionally, Dr. Moody serves as one of the Principal Investigators of the new Duke Collaborative Influenza Vaccine Innovation Centers (CIVICs) where he will conduct basic immunology and virology research to identify potential influenza vaccine candidates.

In addition, the Moody lab has active projects looking at the response to HIV-1, syphilis, and autoimmunity.

Education and Training

  • Fellowship, Pediatric Infectious Diseases, Pediatrics, Duke University, 2003 - 2006
  • Pediatric Chief Resident, Pediatrics, Emory University, 2002 - 2003
  • Pediatric Internship & Residency, Pediatrics, Emory University, 1999 - 2002
  • M.D., Duke University, 1999

Selected Grants and Awards

Publications

Saleh, Ezzeldin, Geeta K. Swamy, M Anthony Moody, and Emmanuel B. Walter. “Parental Approach to the Prevention and Management of Fever and Pain Following Childhood Immunizations: A Survey Study.” Clin Pediatr (Phila) 56, no. 5 (May 2017): 435–42. https://doi.org/10.1177/0009922816675116.

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Fan, Qihua, Cody S. Nelson, Kristy M. Bialas, Flavia Chiuppesi, Joshua Amos, Thaddeus C. Gurley, Dawn Jones Marshall, et al. “Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission.” Clin Vaccine Immunol 24, no. 5 (May 2017). https://doi.org/10.1128/CVI.00510-16.

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Knox, James J., Marcus Buggert, Lela Kardava, Kelly E. Seaton, Michael A. Eller, David H. Canaday, Merlin L. Robb, et al. “T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response.” Jci Insight 2, no. 8 (April 20, 2017). https://doi.org/10.1172/jci.insight.92943.

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Prévost, Jérémie, Daria Zoubchenok, Jonathan Richard, Maxime Veillette, Beatriz Pacheco, Mathieu Coutu, Nathalie Brassard, et al. “Influence of the Envelope gp120 Phe 43 Cavity on HIV-1 Sensitivity to Antibody-Dependent Cell-Mediated Cytotoxicity Responses.” J Virol 91, no. 7 (April 1, 2017). https://doi.org/10.1128/JVI.02452-16.

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Alam, S Munir, Baptiste Aussedat, Yusuf Vohra, R Ryan Meyerhoff, Evan M. Cale, William E. Walkowicz, Nathan A. Radakovich, et al. “Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.” Sci Transl Med 9, no. 381 (March 15, 2017). https://doi.org/10.1126/scitranslmed.aai7521.

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Bonsignori, Mattia, Edward F. Kreider, Daniela Fera, R Ryan Meyerhoff, Todd Bradley, Kevin Wiehe, S Munir Alam, et al. “Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.” Sci Transl Med 9, no. 381 (March 15, 2017). https://doi.org/10.1126/scitranslmed.aai7514.

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Saunders, Kevin O., Nathan I. Nicely, Kevin Wiehe, Mattia Bonsignori, R Ryan Meyerhoff, Robert Parks, William E. Walkowicz, et al. “Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates.” Cell Rep 18, no. 9 (February 28, 2017): 2175–88. https://doi.org/10.1016/j.celrep.2017.02.003.

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Easterhoff, David, M Anthony Moody, Daniela Fera, Hao Cheng, Margaret Ackerman, Kevin Wiehe, Kevin O. Saunders, et al. “Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.” Plos Pathog 13, no. 2 (February 2017): e1006182. https://doi.org/10.1371/journal.ppat.1006182.

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Wiehe, Kevin, Nathan I. Nicely, Bradley Lockwood, Masayuki Kuraoka, Kara Anasti, Sabrina Arora, Cindy M. Bowman, et al. “Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice.” J Immunol 198, no. 3 (February 1, 2017): 1047–55. https://doi.org/10.4049/jimmunol.1601640.

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Williams, LaTonya D., Gilad Ofek, Sebastian Schätzle, Jonathan R. McDaniel, Xiaozhi Lu, Nathan I. Nicely, Liming Wu, et al. “Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.” Sci Immunol 2, no. 7 (January 27, 2017). https://doi.org/10.1126/sciimmunol.aal2200.

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