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Michael Anthony Moody, MD

Associate Professor of Pediatrics
Associate Professor in the Department of Immunology
Member of the Duke Human Vaccine Institute
Campus mail: 2 Genome Ct, MSRB II Room 3007, Durham, NC 27710
Phone: (919) 668-2551
Email address: tony.moody@duke.edu

Tony Moody, MD is an Associate Professor in the Department of Pediatrics, Division of Infectious Diseases and the Department of Immunology at Duke University Medical Center. Research in the Moody lab is focused on understanding the B cell responses during infection, vaccination, and disease. The lab has become a resource for human phenotyping, flow characterization, staining and analysis at the Duke Human Vaccine Institute (DHVI). The Moody lab is currently funded to study influenza, syphilis, HIV-1, and emerging infectious diseases.

Dr. Moody is the director of the Duke CIVICs Vaccine Center (DCVC) at (DHVI) and co-director of the Centers for Research of Emerging Infectious Disease Coordinating Center (CREID-CC). Dr. Moody is co-PI of a U19 program to develop a syphilis vaccine; this program is led by Dr. Justin Radolf at the University of Connecticut. Dr. Moody is also the director of the DHVI Accessioning Unit, a biorepository that provides support for work occurring at DHVI and with its many collaborators around the world by providing processing, shipping, and inventory support for a wide array of projects.

Dr. Moody and his team are involved in many networks studying vaccine response including the Collaborative Influenza Vaccine Innovation Centers (CIVICs), HIV Vaccine Trials Network (HVTN) and the COVID-19 Prevention Network (CoVPN).

Education and Training

  • Fellowship, Pediatric Infectious Diseases, Pediatrics, Duke University, 2003 - 2006
  • Pediatric Chief Resident, Pediatrics, Emory University, 2002 - 2003
  • Pediatric Internship & Residency, Pediatrics, Emory University, 1999 - 2002
  • M.D., Duke University, 1999

Selected Grants and Awards

Publications

Saunders, Kevin O., Laurent K. Verkoczy, Chuancang Jiang, Jinsong Zhang, Robert Parks, Haiyan Chen, Max Housman, et al. “Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models.” Cell Rep 21, no. 13 (December 26, 2017): 3681–90. https://doi.org/10.1016/j.celrep.2017.12.028.

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Williams, Wilton B., Jinsong Zhang, Chuancang Jiang, Nathan I. Nicely, Daniela Fera, Kan Luo, M Anthony Moody, et al. “Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.” Nat Commun 8, no. 1 (November 23, 2017): 1732. https://doi.org/10.1038/s41467-017-01336-3.

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Mohr, Emma L., Dawn M. Dudley, Matthew T. Aliota, Andrea Weiler, Gabrielle Lehrer-Brey, Kim L. Weisgrau, Mariel S. Mohns, et al. “DEVELOPMENT OF A NONHUMAN PRIMATE MODEL OF ZIKA VIRUS INFECTION IN PREGNANT AND NON-PREGNANT RHESUS MACAQUES.” In American Journal of Tropical Medicine and Hygiene, 95:570–570. AMER SOC TROP MED & HYGIENE, 2017.

Scholars@Duke

Han, Qifeng, Wilton B. Williams, Kevin O. Saunders, Kelly E. Seaton, Kevin J. Wiehe, Nathan Vandergrift, Tarra A. Von Holle, et al. “HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces gp41 Antibody Immunodominance in Rhesus Macaques.” J Virol 91, no. 21 (November 1, 2017). https://doi.org/10.1128/JVI.00923-17.

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Phillips, Bonnie, Genevieve G. Fouda, Josh Eudailey, Justin Pollara, Alan D. Curtis, Erika Kunz, Maria Dennis, et al. “Impact of Poxvirus Vector Priming, Protein Coadministration, and Vaccine Intervals on HIV gp120 Vaccine-Elicited Antibody Magnitude and Function in Infant Macaques.” Clin Vaccine Immunol 24, no. 10 (October 2017). https://doi.org/10.1128/CVI.00231-17.

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Wang, Kening, Georgia D. Tomaras, Sinthujan Jegaskanda, M Anthony Moody, Hua-Xin Liao, Kyle N. Goodman, Phillip W. Berman, et al. “Monoclonal Antibodies, Derived from Humans Vaccinated with the RV144 HIV Vaccine Containing the HVEM Binding Domain of Herpes Simplex Virus (HSV) Glycoprotein D, Neutralize HSV Infection, Mediate Antibody-Dependent Cellular Cytotoxicity, and Protect Mice from Ocular Challenge with HSV-1.” J Virol 91, no. 19 (October 1, 2017). https://doi.org/10.1128/JVI.00411-17.

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Bradley, Todd, Justin Pollara, Sampa Santra, Nathan Vandergrift, Srivamshi Pittala, Chris Bailey-Kellogg, Xiaoying Shen, et al. “Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge.” Nat Commun 8 (June 8, 2017): 15711. https://doi.org/10.1038/ncomms15711.

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Saleh, Ezzeldin, Geeta K. Swamy, M Anthony Moody, and Emmanuel B. Walter. “Parental Approach to the Prevention and Management of Fever and Pain Following Childhood Immunizations: A Survey Study.” Clin Pediatr (Phila) 56, no. 5 (May 2017): 435–42. https://doi.org/10.1177/0009922816675116.

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Fan, Qihua, Cody S. Nelson, Kristy M. Bialas, Flavia Chiuppesi, Joshua Amos, Thaddeus C. Gurley, Dawn Jones Marshall, et al. “Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission.” Clin Vaccine Immunol 24, no. 5 (May 2017). https://doi.org/10.1128/CVI.00510-16.

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Knox, James J., Marcus Buggert, Lela Kardava, Kelly E. Seaton, Michael A. Eller, David H. Canaday, Merlin L. Robb, et al. “T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response.” Jci Insight 2, no. 8 (April 20, 2017). https://doi.org/10.1172/jci.insight.92943.

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