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Michael Anthony Moody, MD

Associate Professor of Pediatrics
Associate Professor in the Department of Immunology
Member of the Duke Human Vaccine Institute
Campus mail: 2 Genome Ct, MSRB II Room 3007, Durham, NC 27710
Phone: (919) 668-2551
Email address: tony.moody@duke.edu

Tony Moody, MD is an Associate Professor in the Department of Pediatrics, Division of Infectious Diseases and the Department of Immunology at Duke University Medical Center. Research in the Moody lab is focused on understanding the B cell responses during infection, vaccination, and disease. The lab has become a resource for human phenotyping, flow characterization, staining and analysis at the Duke Human Vaccine Institute (DHVI). The Moody lab is currently funded to study influenza, syphilis, HIV-1, and emerging infectious diseases.

Dr. Moody is the director of the Duke CIVICs Vaccine Center (DCVC) at (DHVI) and co-director of the Centers for Research of Emerging Infectious Disease Coordinating Center (CREID-CC). Dr. Moody is co-PI of a U19 program to develop a syphilis vaccine; this program is led by Dr. Justin Radolf at the University of Connecticut. Dr. Moody is also the director of the DHVI Accessioning Unit, a biorepository that provides support for work occurring at DHVI and with its many collaborators around the world by providing processing, shipping, and inventory support for a wide array of projects.

Dr. Moody and his team are involved in many networks studying vaccine response including the Collaborative Influenza Vaccine Innovation Centers (CIVICs), HIV Vaccine Trials Network (HVTN) and the COVID-19 Prevention Network (CoVPN).

Education and Training

  • Fellowship, Pediatric Infectious Diseases, Pediatrics, Duke University, 2003 - 2006
  • Pediatric Chief Resident, Pediatrics, Emory University, 2002 - 2003
  • Pediatric Internship & Residency, Pediatrics, Emory University, 1999 - 2002
  • M.D., Duke University, 1999

Selected Grants and Awards

Publications

Moody, M. A., T. A. Howard, and R. E. Ware. “Mechanisms of resistance to apoptosis in granulocytes of patients with paroxysmal nocturnal hemoglobinuria.” Blood 92, no. 10 (November 15, 1998): 6B-7B.

Scholars@Duke

Ware, R. E., J. Nishimura, M. A. Moody, C. Smith, W. F. Rosse, and T. A. Howard. “The PIG-A mutation and absence of glycosylphosphatidylinositol-linked proteins do not confer resistance to apoptosis in paroxysmal nocturnal hemoglobinuria.” Blood 92, no. 7 (October 1, 1998): 2541–50.

Scholars@Duke

Vu, H. M., R. de Lorimier, M. A. Moody, B. F. Haynes, and L. D. Spicer. “Conformational preferences of a chimeric peptide HIV-1 immunogen from the C4-V3 domains of gp120 envelope protein of HIV-1 CAN0A based on solution NMR: comparison to a related immunogenic peptide from HIV-1 RF.” Biochemistry 35, no. 16 (April 23, 1996): 5158–65. https://doi.org/10.1021/bi952665x.

Full Text

SPICER, L. D., H. VU, R. DELORIMIER, M. A. MOODY, and B. F. HAYNES. “NMR CONFORMATIONAL STUDIES BY IMMUNOGENIC PEPTIDE-FRAGMENTS DERIVED FROM HIV COAT PROTEIN-GP120.” Journal of Cellular Biochemistry, April 2, 1995, 50–50.

Scholars@Duke

Haynes, B. F., M. A. Moody, C. S. Heinley, B. Korber, W. A. Millard, and R. M. Scearce. “HIV type 1 V3 region primer-induced antibody suppression is overcome by administration of C4-V3 peptides as a polyvalent immunogen.” Aids Res Hum Retroviruses 11, no. 2 (February 1995): 211–21. https://doi.org/10.1089/aid.1995.11.211.

Full Text

Lorimier, R. de, M. A. Moody, B. F. Haynes, and L. D. Spicer. “NMR-derived solution conformations of a hybrid synthetic peptide containing multiple epitopes of envelope protein gp120 from the RF strain of human immunodeficiency virus.” Biochemistry 33, no. 8 (March 1, 1994): 2055–62. https://doi.org/10.1021/bi00174a011.

Full Text

MYERS, D., M. A. MOODY, B. F. HAYNES, and L. D. SPICER. “THE 2-D NMR CHARACTERIZATION OF A 39 RESIDUE IMMUNOGENIC CHIMERIC PEPTIDE DERIVED FROM HIVMN.” Biophysical Journal 66, no. 2 (February 1, 1994): A29–A29.

Scholars@Duke

Liao, H. X., M. C. Levesque, K. Patton, B. Bergamo, D. Jones, M. A. Moody, M. J. Telen, and B. F. Haynes. “Regulation of human CD44H and CD44E isoform binding to hyaluronan by phorbol myristate acetate and anti-CD44 monoclonal and polyclonal antibodies.” J Immunol 151, no. 11 (December 1, 1993): 6490–99.

Scholars@Duke

HAYNES, B. F., J. V. TORRES, A. J. LANGLOIS, D. P. BOLOGNESI, M. B. GARDNER, T. J. PALKER, R. M. SCEARCE, et al. “INDUCTION OF BROADLY CROSS-REACTIVE HIV NEUTRALIZING ANTIBODIES IN PRIMATES USING A PRIME-BOOST REGIMEN OF HYBRID SYNTHETIC GP120 ENVELOPE PEPTIDES.” Aids Research and Human Retroviruses 9 (October 1, 1993): S29–S29.

Scholars@Duke

Haynes, B. F., J. V. Torres, A. J. Langlois, D. P. Bolognesi, M. B. Gardner, T. J. Palker, R. M. Scearce, D. M. Jones, M. A. Moody, and C. McDanal. “Induction of HIVMN neutralizing antibodies in primates using a prime-boost regimen of hybrid synthetic gp120 envelope peptides.” J Immunol 151, no. 3 (August 1, 1993): 1646–53.

Scholars@Duke

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