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Michael Anthony Moody, MD

Associate Professor of Pediatrics
Associate Professor in the Department of Immunology
Member of the Duke Human Vaccine Institute
Campus mail: 2 Genome Ct, MSRB II Room 3007, Durham, NC 27710
Phone: (919) 668-2551
Email address: tony.moody@duke.edu

Tony Moody, MD is an Associate Professor in the Department of Pediatrics, Division of Infectious Diseases and the Department of Immunology at Duke University Medical Center. Research in the Moody lab is focused on understanding the B cell responses during infection, vaccination, and disease. The lab has become a resource for human phenotyping, flow characterization, staining and analysis at the Duke Human Vaccine Institute (DHVI). The Moody lab is currently funded to study influenza, syphilis, HIV-1, and emerging infectious diseases.

Dr. Moody is the director of the Duke CIVICs Vaccine Center (DCVC) at (DHVI) and co-director of the Centers for Research of Emerging Infectious Disease Coordinating Center (CREID-CC). Dr. Moody is co-PI of a U19 program to develop a syphilis vaccine; this program is led by Dr. Justin Radolf at the University of Connecticut. Dr. Moody is also the director of the DHVI Accessioning Unit, a biorepository that provides support for work occurring at DHVI and with its many collaborators around the world by providing processing, shipping, and inventory support for a wide array of projects.

Dr. Moody and his team are involved in many networks studying vaccine response including the Collaborative Influenza Vaccine Innovation Centers (CIVICs), HIV Vaccine Trials Network (HVTN) and the COVID-19 Prevention Network (CoVPN).

Education and Training

  • Fellowship, Pediatric Infectious Diseases, Pediatrics, Duke University, 2003 - 2006
  • Pediatric Chief Resident, Pediatrics, Emory University, 2002 - 2003
  • Pediatric Internship & Residency, Pediatrics, Emory University, 1999 - 2002
  • M.D., Duke University, 1999

Selected Grants and Awards

Publications

Krebs, Shelly J., Young D. Kwon, Chaim A. Schramm, William H. Law, Gina Donofrio, Kenneth H. Zhou, Syna Gift, et al. “Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.” Immunity 50, no. 3 (March 19, 2019): 677-691.e13. https://doi.org/10.1016/j.immuni.2019.02.008.

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Becken, Bradford, Jacob Kilgore, Elizabeth Thompson, and M Anthony Moody. “Right-sided endocarditis from Staphylococcus lugdunensis in a patient with tetralogy of Fallot.” Infect Dis Rep 11, no. 1 (February 26, 2019): 7872. https://doi.org/10.4081/idr.2019.7872.

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Von Holle, Tarra A., and M Anthony Moody. “Influenza and Antibody-Dependent Cellular Cytotoxicity.” Front Immunol 10 (2019): 1457. https://doi.org/10.3389/fimmu.2019.01457.

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Jones, L. D., A. B. Thompson, and M. Anthony Moody. “Vaccine development.” In Genomic and Precision Medicine: Infectious and Inflammatory Disease, 167–83, 2019. https://doi.org/10.1016/B978-0-12-801496-7.00012-5.

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Bonsignori, Mattia, Eric Scott, Kevin Wiehe, David Easterhoff, S Munir Alam, Kwan-Ki Hwang, Melissa Cooper, et al. “Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier.” Immunity 49, no. 6 (December 18, 2018): 1162-1174.e8. https://doi.org/10.1016/j.immuni.2018.10.015.

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Eeden, Charmaine van, Constantinos Kurt Wibmer, Cathrine Scheepers, Simone I. Richardson, Molati Nonyane, Bronwen Lambson, Nonhlanhla N. Mkhize, et al. “V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity.” Cell Rep 25, no. 11 (December 11, 2018): 3123-3135.e6. https://doi.org/10.1016/j.celrep.2018.11.058.

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Fortner, Kimberly B., Geeta K. Swamy, Karen R. Broder, Natalia Jimenez-Truque, Yuwei Zhu, Pedro L. Moro, Jennifer Liang, et al. “Reactogenicity and immunogenicity of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) in pregnant and nonpregnant women.” Vaccine 36, no. 42 (October 8, 2018): 6354–60. https://doi.org/10.1016/j.vaccine.2018.07.012.

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Bradley, Todd, Dimitra Peppa, Isabela Pedroza-Pacheco, Dapeng Li, Derek W. Cain, Ricardo Henao, Vaishnavi Venkat, et al. “RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.” Cell 175, no. 2 (October 4, 2018): 387-399.e17. https://doi.org/10.1016/j.cell.2018.08.064.

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Williams, Wilton Bryan, R Ryan Meyerhoff, Hui Li, Priyamvada Acharya, Guillaume B. E. Stewart-Jones, Kevin Wiehe, Thomas B. Kepler, et al. “Macaque SHIV Induction of 2G12-like Broadly Neutralizing Antibodies.” In Aids Research and Human Retroviruses, 34:38–38. MARY ANN LIEBERT, INC, 2018.

Scholars@Duke

Van, Verna, William Tolbert, George K. Lewis, M Anthony Moody, Marzena Pazgier, and Rebekah Sherburn. “Structural Basis for A32-like Epitopes Involved in ADCC Response of the RV114 Vaccine Trial.” In Aids Research and Human Retroviruses, 34:114–114. MARY ANN LIEBERT, INC, 2018.

Scholars@Duke

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