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Michael Anthony Moody, MD

Associate Professor of Pediatrics
Associate Professor in the Department of Immunology
Member of the Duke Human Vaccine Institute
Campus mail: 2 Genome Ct, MSRB II Room 3007, Durham, NC 27710
Phone: (919) 668-2551
Email address: tony.moody@duke.edu

Tony Moody, MD is an Associate Professor in the Department of Pediatrics, Division of Infectious Diseases and the Department of Immunology at Duke University Medical Center. Dr. Moody is the Director of the Laboratory of B cell Immunotechnology at the Duke Human Vaccine Institute (DHVI). Research in the Moody lab is focused on understanding the B cell responses during the earliest stages of HIV infection. The lab has become a resource for human phenotyping, flow characterization, staining and analysis at DHVI.  Dr. Moody is also the Director of the CHAVI DHVI Repository that provides support for the collaborative work occurring at DHVI and with its many collaborators around the world by providing processing, shipping, and inventory support for a wide array of projects. Additionally, Dr. Moody serves as one of the Principal Investigators of the new Duke Collaborative Influenza Vaccine Innovation Centers (CIVICs) where he will conduct basic immunology and virology research to identify potential influenza vaccine candidates.

In addition, the Moody lab has active projects looking at the response to HIV-1, syphilis, and autoimmunity.

Education and Training

  • Fellowship, Pediatric Infectious Diseases, Pediatrics, Duke University, 2003 - 2006
  • Pediatric Chief Resident, Pediatrics, Emory University, 2002 - 2003
  • Pediatric Internship & Residency, Pediatrics, Emory University, 1999 - 2002
  • M.D., Duke University, 1999

Selected Grants and Awards

Publications

Bradley, Todd, Dimitra Peppa, Isabela Pedroza-Pacheco, Dapeng Li, Derek W. Cain, Ricardo Henao, Vaishnavi Venkat, et al. “RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.” Cell 175, no. 2 (October 4, 2018): 387-399.e17. https://doi.org/10.1016/j.cell.2018.08.064.

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Williams, Wilton Bryan, R Ryan Meyerhoff, Hui Li, Priyamvada Acharya, Guillaume B. E. Stewart-Jones, Kevin Wiehe, Thomas B. Kepler, et al. “Macaque SHIV Induction of 2G12-like Broadly Neutralizing Antibodies.” In Aids Research and Human Retroviruses, 34:38–38. MARY ANN LIEBERT, INC, 2018.

Scholars@Duke

Van, Verna, William Tolbert, George K. Lewis, M Anthony Moody, Marzena Pazgier, and Rebekah Sherburn. “Structural Basis for A32-like Epitopes Involved in ADCC Response of the RV114 Vaccine Trial.” In Aids Research and Human Retroviruses, 34:114–114. MARY ANN LIEBERT, INC, 2018.

Scholars@Duke

Ferdman, Jack, Giuseppe Palladino, Hua-Xin Liao, M Anthony Moody, Thomas B. Kepler, Giuseppe Del Giudice, Philip R. Dormitzer, Stephen C. Harrison, Ethan C. Settembre, and Pirada Suphaphiphat. “Intra-seasonal antibody repertoire analysis of a subject immunized with an MF59®-adjuvanted pandemic 2009 H1N1 vaccine.” Vaccine 36, no. 35 (August 23, 2018): 5325–32. https://doi.org/10.1016/j.vaccine.2018.06.054.

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Chaires, Hector, Goran Bajic, Michael Moody, and Stephen Harrison. “Structure of influenza hemagglutinin antibody from Rhesus Macaque with disulfide bond in its CDRH3.” In Abstracts of Papers of the American Chemical Society, Vol. 256. AMER CHEMICAL SOC, 2018.

Scholars@Duke

Moody, M Anthony. “Strength through Organization: Classifying Antibody Activity against EBOV.” Cell Host Microbe 24, no. 2 (August 8, 2018): 185–86. https://doi.org/10.1016/j.chom.2018.07.015.

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Madani, Navid, Amy M. Princiotto, Linh Mach, Shilei Ding, Jérémie Prevost, Jonathan Richard, Bhavna Hora, et al. “A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge.” Nat Commun 9, no. 1 (June 18, 2018): 2363. https://doi.org/10.1038/s41467-018-04758-9.

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Pardi, Norbert, Michael J. Hogan, Martin S. Naradikian, Kaela Parkhouse, Derek W. Cain, Letitia Jones, M Anthony Moody, et al. “Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.” J Exp Med 215, no. 6 (June 4, 2018): 1571–88. https://doi.org/10.1084/jem.20171450.

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DeKosky, Brandon J., Bo Wang, Morgan Timm, Jiwon Lee, Erica Normandin, John Misasi, Rui Kong, et al. “Functional Interrogation and Mining of Natively-Paired Human V-H:V-L Antibody Repertoires.” In Journal of Immunology, Vol. 200. AMER ASSOC IMMUNOLOGISTS, 2018.

Scholars@Duke

Wills, Saintedym, Kwan-Ki Hwang, Pinghuang Liu, S Moses Dennison, Matthew Zirui Tay, Xiaoying Shen, Justin Pollara, et al. “HIV-1-Specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galactosylceramide Blocking and Phagocytosis.” J Virol 92, no. 7 (April 1, 2018). https://doi.org/10.1128/JVI.01552-17.

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