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Michael Anthony Moody, MD

Associate Professor of Pediatrics
Associate Professor in the Department of Immunology
Member of the Duke Human Vaccine Institute
Campus mail: 2 Genome Ct, MSRB II Room 3007, Durham, NC 27710
Phone: (919) 668-2551
Email address: tony.moody@duke.edu

Tony Moody, MD is an Associate Professor in the Department of Pediatrics, Division of Infectious Diseases and the Department of Immunology at Duke University Medical Center. Dr. Moody is the Director of the Laboratory of B cell Immunotechnology at the Duke Human Vaccine Institute (DHVI). Research in the Moody lab is focused on understanding the B cell responses during the earliest stages of HIV infection. The lab has become a resource for human phenotyping, flow characterization, staining and analysis at DHVI.  Dr. Moody is also the Director of the CHAVI DHVI Repository that provides support for the collaborative work occurring at DHVI and with its many collaborators around the world by providing processing, shipping, and inventory support for a wide array of projects. Additionally, Dr. Moody serves as one of the Principal Investigators of the new Duke Collaborative Influenza Vaccine Innovation Centers (CIVICs) where he will conduct basic immunology and virology research to identify potential influenza vaccine candidates.

In addition, the Moody lab has active projects looking at the response to HIV-1, syphilis, and autoimmunity.

Education and Training

  • Fellowship, Pediatric Infectious Diseases, Pediatrics, Duke University, 2003 - 2006
  • Pediatric Chief Resident, Pediatrics, Emory University, 2002 - 2003
  • Pediatric Internship & Residency, Pediatrics, Emory University, 1999 - 2002
  • M.D., Duke University, 1999

Selected Grants and Awards

Publications

Easterhoff, David, Justin Pollara, Kan Luo, William D. Tolbert, Brianna Young, Dieter Mielke, Shalini Jha, et al. “Boosting with AIDSVAX B/E enhances Env constant region 1 and 2 antibody-dependent cellular cytotoxicity breadth and potency..” J Virol, November 27, 2019. https://doi.org/10.1128/JVI.01120-19.

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Jones, Letitia, Amelia Thompson, and michael Moody. “Vaccine Development.” In Genomic and Precision Medicine Infectious and Inflammatory Disease. Academic Press, 2019.

Scholars@Duke

Nyanhete, Tinashe E., Alyse L. Frisbee, Todd Bradley, William J. Faison, Elizabeth Robins, Tamika Payne, Stephanie A. Freel, et al. “HLA class II-Restricted CD8+ T cells in HIV-1 Virus Controllers..” Sci Rep 9, no. 1 (July 15, 2019). https://doi.org/10.1038/s41598-019-46462-8.

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Krebs, Shelly J., Young D. Kwon, Chaim A. Schramm, William H. Law, Gina Donofrio, Kenneth H. Zhou, Syna Gift, et al. “Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual..” Immunity 50, no. 3 (March 19, 2019): 677-691.e13. https://doi.org/10.1016/j.immuni.2019.02.008.

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Becken, Bradford, Jacob Kilgore, Elizabeth Thompson, and M Anthony Moody. “Right-sided endocarditis from Staphylococcus lugdunensis in a patient with tetralogy of Fallot..” Infect Dis Rep 11, no. 1 (February 26, 2019). https://doi.org/10.4081/idr.2019.7872.

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Von Holle, Tarra A., and M Anthony Moody. “Influenza and Antibody-Dependent Cellular Cytotoxicity..” Front Immunol 10 (2019). https://doi.org/10.3389/fimmu.2019.01457.

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Bonsignori, Mattia, Eric Scott, Kevin Wiehe, David Easterhoff, S Munir Alam, Kwan-Ki Hwang, Melissa Cooper, et al. “Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier..” Immunity 49, no. 6 (December 18, 2018): 1162-1174.e8. https://doi.org/10.1016/j.immuni.2018.10.015.

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Eeden, Charmaine van, Constantinos Kurt Wibmer, Cathrine Scheepers, Simone I. Richardson, Molati Nonyane, Bronwen Lambson, Nonhlanhla N. Mkhize, et al. “V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity..” Cell Rep 25, no. 11 (December 11, 2018): 3123-3135.e6. https://doi.org/10.1016/j.celrep.2018.11.058.

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Fortner, Kimberly B., Geeta K. Swamy, Karen R. Broder, Natalia Jimenez-Truque, Yuwei Zhu, Pedro L. Moro, Jennifer Liang, et al. “Reactogenicity and immunogenicity of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) in pregnant and nonpregnant women..” Vaccine 36, no. 42 (October 8, 2018): 6354–60. https://doi.org/10.1016/j.vaccine.2018.07.012.

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Bradley, Todd, Dimitra Peppa, Isabela Pedroza-Pacheco, Dapeng Li, Derek W. Cain, Ricardo Henao, Vaishnavi Venkat, et al. “RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses..” Cell 175, no. 2 (October 4, 2018): 387-399.e17. https://doi.org/10.1016/j.cell.2018.08.064.

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