New and competing renewal awards for November 2021 and December 2021

The following is a select list of new and competing renewal awards that were made to faculty in the Department of Pediatrics for the months of November 2021 to December 2021.  

November 2021

Samia Aleem (Neonatology) received an award from Airway Therapeutics for $95,573 for a project entitled, Safety and Tolerability of AT-100 (RHSP-D) in Preterm Neonates at High Risk for Development of Bronchopulmonary Dysplasia. The project period is 10/27/2021-09/30/2022. 

Michael Freemark (Endocrinology) and Elizabeth Greene received an award from Lawson Wilkins Pediatric Endocrine Society in the amount of $50,000 for a project entitled, Effects of Metformin on Influenza Outcomes. The project period is 07/01/2021-06/30/2022. 

Rasheed Gbadegesin (Nephrology) received an award from Travera Therapeutics in the amount $194,558 for a project entitled, A Phase Open-Label Single-Arm Cohort Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Sparsentan Treatment in Pediatric Subjects with Selected Proteinuric Glomerular Diseases. The project period is 11/18/2021-10/31/2023. 

Dwight Koeberl (Medical Genetics) received an award from Moderna Therapeutics in the amount of $829,267 for a project entitled, A Phase 1/2, Global, Open-Label, Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the MRNA-3927-P101 Study. The project period is 11/01/2021-10/31/2029. 

William Steinbach (Infectious Diseases) received an award from Sfunga Therapeutics in the amount of $94,990 for a project entitled, Expanded Pre-Clinical Aspergillosis Experimental Plan for Sfu-AM-2-19. The project period is 11/01/2021-06/01/2022. 

Muhammad Zafar (Neurology) received an award from Neurocrine Biosciences in the amount of $177,992 for a project entitled, A Phase 2 Multicenter Randomized Double-blind Placebo-Controlled Parallel Group Study to Assess the Efficacy Safety Tolerability and Pharmacokinetics of NBI - 827104 in Pediatric Subjects with Epileptic Encephalopathy with Continuous Spike and Wave During Sleep. The project period is TBD. 

December 2021

Karl-Dimiter Bissig (Medical Genetics) received an award from Avachrome in the amount of $153,746 for a project entitled, Validation of Next Generation Humanized Mouse Models. The project period is 01/01/2022-12/31/2023. 

Laurie Graves (Hematology-Oncology) and Lars Wagner (Hematology-Oncology) received an award from Hyundai Hope on Wheels (HHO/W) in the amount of $200,000 for a project entitled, Modeling Tumor Heterogeneity and Therapy Resistance in Osteosarcoma Using Patient-Derived Organoids. The project period is 12/31/2021-12/31/2023. 

Priya Kishnani (Medical Genetics) received an award from Johannes Kepler University in the amount of $173,783 for a project entitled, Functional Testing of VUS in ALPL in the Causation of HPP. The project period is 12/01/2021-06/30/2024. 

Christian Stackhouse (Hematology-Oncology) and Corinne Linardic (Hematology-Oncology) received an award from Alex’s Lemonade Stand in the amount of $150,000 for a project entitled, Development of RNAi-based Therapeutics to Target Oncogenic IncRNAs in Rhabdomyosarcoma. The project period is 01/17/2022-1/16/2025.

Congratulations to these faculty on their awards and best wishes to them in their investigative work.

Christoph Hornik, MD, MPH
Vice Chair, Research
Associate Professor of Pediatrics
Division of Critical Care Medicine
Chief, Division of Quantitative Sciences
christoph.hornik@duke.edu

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