The following are new and competing renewal awards made to faculty in the Department of Pediatrics for the months of February 2022 through September 2022. Congratulations to these faculty on their awards and best wishes to them in their investigative work.
February 2022
Karl-Dimiter Bissig (Medical Genetics) received an award from Tune Therapeutics in the amount of $285,764 for a project entitled, Epigenetic Modulation of Therapeutic Targets in FRG Mice. The project period is 02/18/2022-02/28/2023.
Genevieve Fouda (Infectious Diseases) received an award from Johns Hopkins University/NIH in the amount of $465,846 for a project entitled, Pediatric Adolescent Virus Eradiation (PAVE) Martin Delaney Collaboratory. The project period is 08/16/2021-04/30/2026.
Kristy Pahl (Hematoloy-Oncology) received an award from Competitive Drug Development International in the amount of $9,839 for a project entitled, Evidence-based Feasibility (Ebf) process for a planned study of asundexian in children up to 18 years of age diagnosed with acute ischaemic stroke (AIS) or covert brain infarcts (CBI). The project period is 01/01/2022-01/31/2024.
Edward C. Smith (Neurology) received an award from Parent Project Muscular Dystrophy in the amount of $5,000 for a project entitled, 2022 PPMD CDCC Grant. The project period is 01/01/2022-12/31/2022.
Lars Wagner (Hematology-Oncology) received an award from Valent Technologies in the amount of $78,991 for a project entitled, Pilot Pharmacokinetic Study of VAL-413 in Patients with Recurrent pediatric Solid Tumors. The project period is 01/13/2022-03/23/2026.
March 2022
Gregory Fleming (Cardiology) received an award from Medtronic Inc. in the amount of $153,250 for a project entitled, Harmony TPV Post-Approval Study (Harmony PAS 2). The project period is 03/24/2022-12/31/2031.
Priya Kishnani (Medical Genetics) received an award from Takeda Technologies in the amount of $240,599 for a project entitled, Immunophenotyping of patients with MPS II treated with enzyme replacement therapy. The project period is 01/31/2022-10/31/2024.
Andrew Landstrom (Cardiology) received an award from the John Taylor Babbitt Foundation in the amount of $75,000 for a project entitled, Establishing the Role of DSP in Inflammation-Induced ARRH. The project period is 03/01/2022- 02/28/2023.
Alisha Mavis (Gastroenterology, Hepatology, and Nutrition) received an award from Albireo AB in the amount of $355,561 for a project entitled, A double-blind Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Odevixibat (A4250) in Children with biliary Atresia Who have Undergone a Kasi Hepatoportoenterostomy. The project period is 03/14/2022-03/02/2024.
Alisha Mavis (Gastroenterology, Hepatology, and Nutrition) received an award from Lurie Children’s Hospital in the amount of $54,640 for a project entitled, Pediatric Acute Liver Failure Immune Response Network. The project period is 06/15/2021-05/1/2026.
Richard Noel (Gastroenterology, Hepatology, and Nutrition) received an award from The Mario Family Foundation in the amount of $454,000 for a project entitled, An Invitation to Support the Division of Pediatric Gastroenterology, Hepatology and Nutrition -Option 2. The project period is 01/01/2022-12/31/2026.
Vinod Prasad (Transplant and Cellular Therapy) received an award from SymBio Pharmaceuticals in the amount of $66,277 for a project entitled, A Phase 2a Open-label Multiple Ascending Dose Confirmation Study of the Safety and Tolerability of Intravenous Brincidofovir in Subjects with Adenovirus Infection. The project period is 02/23/2022-12/02/2025.
John Sleasman (Allergy and Immunology) received an award from Enzyvant in the amount of $1,115,775 for a project entitled, Congenital Athymia Patient Registry. The project period is 02/28/2022-02/27/2027.
Edward Smith (Neurology) received an award from Sarepta Therapeutics in the amount of $278,851 for a project entitled, A Phase 3 Multinational, Randomized, Double-Blind Placebo Controlled Systemic Gene Delivery Study to Evaluate the Safety and Efficacy of SRP 9001 in Subjects with Duchenne Muscular Dystrophy. The project period is 03/04/2022-12/31/2022.
Klaus Werner (Neurology) received an award from Noema Pharma in the amount of $169,182 for a project entitled, A Phase 2b Multicenter 30 week, Prospective Cross-over Double-blind Randomized Placebo-controlled Study Followed by a 52-week Open Label Extension Study to Evaluate the Efficacy and Safety of Basimglurant Adjunctive to Ongoing Anticonvulsive. The project period is 03/01/2022-05/01/2024.
April 2022
Christoph Hornik (Critical Care Medicine) received an award from the National Institutes of Health/NICHD for a project entitled, Digoxin Pharmacodynamics in Infants with Heart Failure due to Single Ventricle Congenital Heart Disease. The project period is 04/01/2022-02/28/2026.
Priya Kishnani (Medical Genetics) received an award from Takeda Pharmaceutical Company, LLC for a project entitled, Medical Education and Awareness Program for Future Health Care Providers in Genetics for LSD. The project period is 04/01/2022-03/31/2023.
Priya Kishnani (Medical Genetics) received an award from Genzyme Corporation for project entitled, Factors in Immune Response Affecting Long-term Treatment Outcomes in Pompe disease (CRIM). The project period is 03/07/2022-12/31/2024.
Priya Kishnani (Medical Genetics) received an award from Genzyme Corporation for a project entitled, Understanding cognitive and neurological pathologies in infantile Pompe disease CNS. The project period is 03/17/2022-12/31/2024.
Corinne Linardic (Hematology-Oncology) received an award from the Alex Lemonade Stand for a project entitled, Therapeutic Potential and Us of Novel CRISPR Technology for IncRNA Knockdown in Rhabdomyosarcoma. The project period is 05/23/2022-07/15/2022.
Andrew Landstrom (Cardiology) received an award from the Hartwell Foundation for a project entitled, Evaluating Wnt-Modulators as a Therapy for Treatment of Arrhythmic Cardiomyopathy In Vivo. The project period is 04/01/2022-03/31/2025.
Baodong Sun (Medical Genetics), received an award from the National Institutes of Health/NIAMSD for a project entitled, Gene Therapy for Glycogen Storage Disease Type III. The project period is 04/01/2022-03/31/2023.
Elizabeth Thompson (Cardiology) and Kanecia Zimmerman (Critical Care Medicine) received an award from Thrasher Research Fund forr a project entitled, Optimizing Caffeine Exposure to Reduce Post-Cardiopulmonary Bypass Acute Kidney Injury in Neonates. The project period is 01/01/2022-12/31/2023.
Emmanuel Walter (Infectious Diseases) received an award from Leidos Biomedical Research, Inc./NIH for a project entitled, COVID-19 Adaptive Variant Immunologic Landscape Trial or COVAIL Trial. The project period is 03/30/2022-12/31/2023.
May 2022
Eileen Chambers (Nephrology) received an award from Boston Children’s Hospital for a project entitled, Advancing Transplantation Outcomes in Children. The project period is 09/07/2021-06/30/2028.
Rasheed Gbadegesin (Nephrology) received an award from Fibrogen, Inc. for a project entitled, FGN-Ped-Clin-o2 (SSU). The project period is 04/27/2022-04/30/2023.
Elizabeth Gifford (Sanford School of Public Policy), Jillian Hurst (Infectious Diseases) and Lindsay Terrell (Child Abuse and Neglect) received an award from The Duke Endowment for a project entitled, Avenues for Prevention and Early Intervention to Address Child Maltreatment. The project period is 07/01/2022-06/30/2024.
Laurie Graves (Hematology-Oncology) received an award from MIB Agents Family Fund Award for travel to the Factor Conference. The project period is 040/01/2022-06/30/2022.
Neil Nenard Bursac (Biomedical Engineering) and Andrew Landstrom (Cardiology) received an award from the National Institutes of Health/NIBIB for a project entitled, Engineered BacNav and BacCav for Improved Excitability and Contraction. The project period is 05/01/2022-01/31/2026.
Monica Lemmon (Neurology) received an award from the University of California of San Francisco for a project entitled, NSR-Gene (Neonatal Seizure Registry, Genetics of PostNeonatal Epilepsy). The project period is 04/01/2022-03/31/2027.
Priya Kishnani (Medical Genetics) received an award from Kriya Therapeutics Project Addendum for a project entitled, AAV Gene Therapy for the Treatment of GSD IX Y2: Determination of Titer fof Duke AAVs using Kriya Titering. The project period is 05/26/2022-12/31/2022.
Priya Kishnani (Medical Genetics) received an award from Kriya Therapeutics Project Addendum for a project entitled, AAV Gene Therapy for the Treatment of GSC IX y2: Determination of Efficacy between Duke Plasmids and Kriya Plasmids for Restoring PHKG22. The project period is 04/28/2022-12/31/2022.
Monica Lemmon (Neurology) received an award from the University of California of San Francisco for a project entitled, NSR-Gene (Neonatal Seizure Registry, Genetics of PostNeonatal Epilepsy). The project period is 04/01/2022-03/31/2027.
Kristy Pahl (Hematology-Oncology) received an award from Children’s Hospital of LA for a project entitled, Prospective Validation of a Venous Thrombosis Risk Assessment Model in Critically Ill Children from the CHAT Registry (CHAT 1901). The project period is 02/01/2022-06/30/2022.
Jennifer Rothman (Hematology-Oncology) received an award from the North Carolina Department of Health and Human Services for a project entitled, NC Sickle Cell Contract. The project period is 06/01/2022-05/31/2023.
Sarah Young (Medical Genetics) received an award from Research Triangle Institute International for a project entitled, INewborn Screening Pilot Studies IDIQ with TO B, MPSII. The project period is 09/28/2021-09/27/2023.
Muhammad Zafar (Neurology) received an award from Neurocrine Bioscience for a project entitled, NBI-827104-CSWS2025. The project period 05/06/2022-08/05/2024.
June 2022
Jennifer Hoffman (Nicholas School of the Environment) and Jillian Hurst (Infectious Diseases) received an award from the National Institutes of Health for a project entitled, Impact of Early-life Exposure to Semi-Volatile Organic Compounds (SVOCs) on Neonatal and Early Childhood. The project period is 02/01/2022-01/31/2027.
Priya Kishnani (Medical Genetics) received an award from Kriya Therapeutics for a project entitled, AAV Gene Therapy for the Treatment of Glycogen Storage Disease IX y2. The project period is 03/02/2022-12/31/2022.
Priya Kishnani (Medical Genetics) received an award from Kriya Therapeutics for a project entitled, AAV-mPhkg2 Gene Therapy for the Treatment of GSC IXy2. The project period is 06/16/2022-03/31/2023.
Michael Moody (Infectious Diseases) received an award from University of North Carolina-Chapel Hill/Bill and Melinda Gates Foundation for a project entitled, Genomic Epidemiology of Treponema Pallidum Strains Infecting Women and Men in Low-Income Countries to Inform Syphilis Vaccine Development (INV-036560). The project period is 11/02/2021-10/31/2022.
Vinod Prasad received an award from Allovir, Inc. for a project entitled”AlloVirP-105” The project period is 05/23/2022-03/31/2025.
Sharla Rent received an award from the National Palliative Care Research Center for a grant entitled” Supporting Families after Perinatal Loss in Tanzania”. The project period is 07/01/2022-06/30/2024.
Vandana Shashi (Medical Genetics) received a supplemental award from the National Institutes of Health/NHGRI for a project entitled, An Integrated and Diverse Genomic Medicine Program for Undiagnosed Diseases. The project period 07/01/2022-06/30/2023.
Ashley Stark (Neonatology) and Rachel Greenberg (Neonatology) received an award from Thrasher Research Fund for a project entitled, Pharmacokinetics of Clonidine Administered in the Infant Population. The project period is 07/01/2022-06/30/2024.
Lars Wagner (Hematology-Oncology) received an award from Children’s Hospital of Philadelphia for a project entitled, Longitudinal Multimodal Assessment of Neuropsychological. The project period is 06/01/2022-05/31/2023.
Emanuel Walter (Infectious Diseases) received an award from Clinetic Inc. for a project entitled, EHR Surveillance of Lower Respiratory Tract (LRTI) and Respiratory Syncytial Virus (RSV) in Infants. The project period is 05/16/2022-03/14/2023.
Sarah Young (Medical Genetics) received an award from Research Triangle Institute for a project entitled, National Screening Pilot Studies IDIQ with TO B, MPS II. The project period 09/28/2021-09/27/2027.
July 2022
Deeksha Bali (Medical Genetics) received an award from JCR Pharma Core Lab for a project entitled, Method Development and Data Validation for MPS I Clinical. The project dates are 07/01/2022-06/30/2023.
Rasheed Gbadegesin (Nephrology) received an award from Boehringer Ingelheim Pharmaceuticals, Inc for a project entitled, Boehringer-Ingelheim FSGS 1434-0004. The project dates are 07/05/2022-05/01/2024.
Andrew Landstrom (Cardiology) received an award from Additional Ventures for a project entitled, Leveraging Induced Pluripotent Stem Cells to Define the Developmental Drivers of Hypoplastic Left Heart Syndrome. The project period is 06/01/2022-04/30/2025.
Jason Lang (Pulmonary and Sleep Medicine) received an award from National Institute of Health/National Institute of Child Health for a project entitled, Safety of Sildenafil in Premature Infants at Risk of Bronchopulmonary Dysplasia (Sildenafil 2.0). The project period is 06/14/2022-10/13/2025.
Corinne Linardic (Hematology-Oncology) received an award from Public Health Institute for a project entitled, Committee Leadership: COG NCTN Network Group Operations C. The project dates are 03/01/2022-02/28/2023.
Michael Smith (Infectious Diseases) received an award from Pfizer for a project entitled, PfizerC4671026. The project dates 6/08/2022-05/07/2024.
Shatha Yousef (Pulmonary and Sleep Medicine) received an award from Cystic Fibrosis Foundation for a project entitled, Cystic Fibrosis Foundation. The project period is 07/01/2022-06/30/2023.
Kanecia Zimmerman (Critical Care Medicine) received an award from Research Triangle International/NHLBI Non -Federal 1OT2HL156812-01 for a project entitled, RECOVER Infrastructure Clinical Trials Data Coordinating Center Initiative. The project period is 06/01/2022-05/31/2023.
August 2022
Andrea Bauchat (Transplant and Cellular Therapy) received an award from the National Marrow Donor Program for a project entitled, Hematopoietic Cell Transplantation Using Treosulfan-Based Conditioning for the Treatment of Bone Marrow Failure Diseases BMT CTN Protocol #1904. The project period is 06/15/2022-06/14/2023.
Rachel Greenberg (Neonatology) and Daniel Benjamin (Infectious Diseases) received an award from the National Institutes of Health for a project entitled, PTN 2.) TO#13 Improving Off-label Medication Use in Children. The project period is 09/28/2022-09/27/2026.
Priya Kishnani (Medical Genetics) received an award from Sanofi US for a project entitled Pompe NcOMPC09701. The project period is 07/19/2022-01/31/2024.
Andrew Landstrom (Cardiology) received an award from the National Institutes of Health/NHLBI for a project entitled, Exploring the Role of ATP1A3 Mutations in Sudden Unexplained Death in Epilepsy. The project period is 08/22/2022-06/30/2027.
Corinne Linardic (Hematology-Oncology) received an award from Massachusetts General Hospital/CureSearch for Children’s Cancer for a project entitled, Targeting P53 in Childhood Rhabdomyosarcoma. The project period is 07/01/2022-10/31/2022.
Corinne Linardic (Hematology-Oncology) received an award from RYVU Therapeutics for a project entitled, Pre-Clinical Studies of CDK* Human Fusion-Positive Rhabdomyosarcoma. The project period is 08/01/2022-07/31/2024.
Kathleen McGann (Infectious Diseases) received an award from DHHS, PHS, HRSA for a project entitled, Ryan White HIV/AIDS Program Part D Coordinated HIV Services. The project period is 08/01/2022-07/31/2026.
Jennifer Rothman (Hematology-Oncology) received an award from Agios Pharmaceutical for a project entitled, AG348-C-023. The project period is 04/29/2022-01/31/2026.
Sarah Young (Medical Genetics) received an award from Aro Biotherapeutics for a project entitled, Evaluation of Urinary HeX4 in Pompe and Wilid-Type Mice. The project period is 07/26/2022-04/30/2023.
September 2022
M. Charles Cotten (Neonatology) received an award from Boston Children’s Hospital for a project entitled, Consortium of MRI Biomarkers in MRI Biomarkers in Neonatal Encephalopathy (COMBINE). The project period is 07/01/2022-04/30/2023.
Areeg El-Gharbawy (Medical Genetics) received an award from Moderna Therapeutics for a project entitled, GSC1A Treat with MRNA-3745. The project period is 08/19/2022-12/31/2024.
Christoph Hornik (Critical Care Medicine), Rachel Greenberg (Neonatology), and Asheley Skinner (General Internal Medicine), received an award for a project entitled, Duke HEAL R-DEC. The project period is 09/23/2022-08/31/2027.
Priya Kishnani (Medical Genetics) received an award from Kriya Therapeutics for a project entitled, Untargeted Transcriptomics of PHKG2-/Liver and Plasma (The Project). The project period is 09/20/2022-12/31/2022.
Corinne Linardic (Hematology-Oncology) received a supplemental award from National Institutes of Health/NCI for a project entitled, Screening for Cys-Reactive Ligands to Target PAX3-FOX01. The project period is 08/01/2022-07/31/2023.
Jennifer Rothman (Hematology-Oncology) received an award from Sanofi US for a project entitled, Study on Caplacizumab-Treated Pediatrics Patients. The project period is 08/31/2022-01/15/2023.
Vandana Shashi (Medical Genetics) received a supplemental award from National Institutes of Health/NHGRI for a project entitled, An Integrated and Diverse Genomic Medicine Program for Undiagnosed Diseases. The project period is 09/01/2022-06/30/2023.
Edward Smith (Neurology) received an award from Parent Project Muscular Dystrophy for a project entitled, Duchenne Outcomes Research Interchange Data Enrichment through HER Extraction. The project period is 08/31/2022-08/31/2023.
P. Brian Smith (Neonatology) received an award from the National Institutes of Health for a project entitled, ACT-NOW Data Sustainability-ECHO Supplement. The project period 08/22/2022-08/31/2023.
P. Brian Smith (Neonatology) and Rachel Greenberg (Neonatology) received an award from the National Institutes of Health for a project entitled, ECHO Administrative Supplement-Neonatal Opioid Trials (ACT NOW: ESC Weaning). The project period is 08/24/2022-08/31/2023.
Emmanuel Walter (Infectious Diseases) received an award from Pfizer for a project entitled, Master Phase 1/2/3 Protocol to Investigate BNT 162b2 RNA-Based Vaccine Candidate in Healthy Children. The project period is 09/26/2022-09/20/2024.
Emmanuel Walter (Infectious Diseases) received an award from the Centers for Disease Control and Prevention for a project entitled, US Platform to Measure Effectiveness of Season Influenza, COVID-19 and other Respiratory Virus Vaccines for the Prevention of Acute Illness in Ambulatory Settings. The project period is 09/30/2022-09/29/2027.
Charles Wood (General Pediatrics and Adolescent Health) received an award from the National Institutes of Health/NICHHD for a project entitled, POWER: Predicting Obesity with Enhanced HER Resources. The project period is 09/01/2022-08/31/2027.
Noelle Younge (Neonatology) received a supplemental award from the National Institutes of Health/NIDDK for a project entitled, The Microbiome and Metabolism in Postnatal Growth Failure. The project period is 04/01/2022-12/31/2023.