The following are new and competing renewal awards made to faculty in the Department of Pediatrics for the months of February 2021 through September 2021. Congratulations to these faculty on their awards and best wishes to them in their investigative work.
February 2021
Kaveh Ardalan, MD (Rheumatology) received an award from the Rheumatology Research Foundation in the amount of $ 375,000 for an award entitled, Psychological Stress and Cardiovascular Heart in Juvenile Lupus and Dermatomyositis. The project period is 07/01/2021-06/30/2024.
Karl-Dimiter Bissig, MD, PhD (Medical Genetics) and William Lagor, PhD (Molecular Physiology and Biophysics / Baylor) received his transfer award from National Institutes of Health/NHLBI in the amount of $549,652 for a project entitled, Therapeutic Potential of CRISPR/Cas9 Genome Engineering in Humanized Mouse. The project period is 02/01/2021-04/30/2021.
Yeh-Chung Chang, MD (Infectious Diseases) received an award from Merck Sharp & Dohme Corp. in the amount of $132,268 or a project entitled, A Phase 2 Open-Label Single-Arm, Sequential-Panel Study to Evaluate the Pharmacokinetics, Safety and Tolerability o Posaconazole (PoS, MK 5592) in Pediatric Participants from Birth to < 2 Years of age with Invasive Fungal Infection. The project period is 09/30/2020-06/30/2025.
C. Michael Cotton, MD (Neonaology) received bridge funding for an additional two years from the National Institutes of Health/NICHD in the amount of $557,566 for the continuation of the Eunice Kennedy Shriver NICHD Cooperative Multicenter Neonatal Research Network. The project period is 04/01/2021-03/31/2023.
Jennifer Li, MD (Cardiology) received an award from the New England Research Institute in the amount of $151,110 for a project entitled, The NIH Longitudinal Study for Multisystem Inflammatory Syndrome Therapies in Children. The project period is 01/01/2021-06/30/2025.
Lars Wagner, MD (Hematology-Oncology) received an award from Nemours Foundation in the amount of $37,558 for a project entitled, Implementing Family Psychosocial Risk Screening for Pediatric Healthy Equity. The project period is 01/01/2021-12/31/2021.
Lars Wagner, MD (Hematology-Oncology) received an award from H. Lee Moffitt Cancer Center and Research Institute in the amount of $10,087 for a project entitled, Evolutionary Inspired Therapy for Newly Diagnosed, Metastatic Fusion Positive Rhabdomyosarcoma. The project period is 12/01/2020-07/01/2021.
Emmanuel Walter, MD, MPH (Infectious Diseases) received an award from Pfizer, Inc. in the amount of $687,913 for a project entitled, A Phase 1, Open-Label Dose-Finding and Phase 2/3 Placebo-Controlled, Observer-Blinded Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Sars-Cov-2 RNA Vaccine Candidate Against Covid-19 in Healthy Children 5 to 12 years of Age. The project period is 02/15/2021-02/14/2023.
March 2021
Danny Benjamin Jr, MD, PhD, MPH (Infectious Diseases) and Michael Cohen-Wolkowiez, MD, PhD (Infectious Diseases) received an award from the Food and Drug Administration in the amount of $500,000 for a project entitled, Global Pediatric Clinical Trials Network-Supplement Award Period #4. The project period is 09/01/2020-08/31/2022.
Danny Benjamin Jr, MD, PhD, MPH (Infectious Diseases) and Kanecia Zimmerman, MD (Critical Care Medicine) received an award from the North Carolina Department of Public Instruction in the amount of $500,000 for a project entitled, ABCs of North Carolina Plan A. The project period is 03/26/2021-09/15/2021.
Eileen Chambers, MD (Nephrology) received an award from National Institutes of Health/NICHD in the amount of $442,750 for a project entitled, Development of a Novel Acoustofluidic Device for Targeted Antibody Removal in Pediatrics Organ Transplant Rejections. The project period is 04/01/2021-03/31/2023.
Michael Cohen-Wolkowiez, MD, PhD (Infectious Diseases) (contact PI) and Christoph Hornik, MD, MPH (Critical Care Medicine) (Lead) received an award from the National Institutes of Health/NIMHHD in the amount of $9,520,571 for a project entitled, RADx-UP Say Yes Covid Test Study. The project period is 03/08/2021--01/31/22.
Gregory Crawford, PhD (Medical Genetics), Charles Gersbach, PhD (Biomedical Engineering) and Patrick Sullivan, MD (UNC/Psychiatry and Genetics) received an award from National Institutes of Health/NIMH in the amount $8,050,699 for a project entitled, Beyond GWAS: High Throughput Functional Genomics & Epigenome Editing to Elucidate the Effects of Genetic Associations for Schizophrenia. The project period is 04/01/2021-01/31/2026.
Dorothy Dow, MD, MScGH (Infectious Diseases) received an award from National Institutes of Health/NIMH in the amount of $2,534,716 for a project entitled, A Mental Health Intervention to Improve HIV Outcomes in Tanzanian Youth. The project period 04/01/2021-01/31/2026.
Matthew Kelly, MD, MPH (Infectious Diseases) received an award from Cornell University in the amount of $45,149 for a project entitled, Pediatric Research Immune Network on SARS-CoV-2 and MIS-C (PRISM). The project period is 03/01/2021-08/31/2022.
Talal Mousallem, MD (Allergy and Immunology) received an award from Leadiant Biosciences, Inc in amount of $57,295 project entitled, Single Arm, Open-Label Multicenter, Registry Study of Revcovi (elapagademase-lvlr) Treatment in ADA-SCID Patients Requiring Enzyme Replacement Therapy. The project period is 03/17/2021-06/30/2021.
Ann Reed, MD (Rheumatology) and Corinne Linardic, PhD (Hematology-Oncology) received an award from National Institutes of Health/ NICHD in the amount of $1,571,400 for a project entitled, Duke Center for Advancement of Child Health (CAtCH). The project period is 04/01/2021-03/31/2026.
Edward Smith, MD (Neurology) received an award from the Muscular Dystrophy in the amount of $5,000 for a project entitled, 2021 PPMD CDCC. The project period is 01/01/2021-12/31/2021.
Lars Wagner, MD (Hematology-Oncology) received an award from Children’s Hospital of Philadelphia/NIH in the amount of $5,001 for a project entitled, NIH COG Pediatric Early Phase Clinical Trial Network Grant (PEP-CTN). The project period is 08/01/2020-07/31/2023.
Lars Wagner, MD (Hematology-Oncology) received an award from Children’s Hospital of Philadelphia/NIH in the amount of $5,901 for a project entitled, Specimen Banking Supplements. The project period is 03/01/2020-02/28/2021.
Lars Wagner, MD (Hematology-Oncology) received an award from Moffitt Cancer Center in the amount of $ 24,072 for a project entitled, A Phase IB/II study to evaluate the Safety, Feasibility and Efficacy of Nivolumab or Nivolumab in Combination with 5-Azacytidine in Patients with Recurrent Resectable Osteosarcoma. The project period is 04/01/2020-06/30/2022.
April 2021
Danny Benjamin Jr, MD, PhD, MPH (Infectious Diseases), Adrian Hernandez, MD (Medicine-Cardiology), and Susanna Naggie, MD (Medicine-Infectious Diseases) received an award from the National Center for Advancing Translational Sciences in the amount of $153,848,390 for an award entitled, ACTIV 6 COVID-19 Outpatient Randomized Trial to Evaluate Efficacy of Repurposed Medications. The project period is 04/17/2021-03/31/2023.
Angelique Boutzoukas, MD (Infectious Diseases), Danny Benjamin Jr, MD, PhD, MPH (Infectious Diseases), Michael Cohen-Wolkowiez, MD, PhD (Infectious Diseases), and Kanecia Zimmerman, MD (Critical Care Medicine) received an award from the Thrasher Foundation in the amount of $26,750 for an award entitled, Duration of Post-Discontinuation Antibiotic Exposures in Premature Infants and Associated Outcomes. The project period is 07/01/2021-06/30/2023.
Rasheed Gbadegesin, MD, MBBS (Nephrology) received an award from the National Institutes of Health/NICHD in the amount of $442,750 for an award entitled, Genetic Basis of Corticosteroid Response in Childhood Nephrotic Syndrome. The project period is 04/01/2021-03/31/2023.
Ronald Goldberg, MD (Neonaology) received an award from the Zeist Foundation in the amount of $300,000 for an award entitled, Jean and George Brumley Jr. Clinical Scholars Program. The project period is 04/01/2021-03/31/2024.
Andrew Landstrom, MD, PhD (Cardiology) and Robin M. Perelli (Graduate Student) received an award from the American Heart Association in the amount of $63,040 for an award entitled, Establishing Wnt Signaling-Mediated Pro-Arrhythmic Cardiac Remodeling. The project period is 04/01/2021-03/31/2023.
Corinne Linardic, MD, PhD (Hematology-Oncology) and Crystal Chiu (Undergraduate Student) received an award from Alex’s Lemonade Stand in the amount of $5,000 for an award entitled, Novel Regulators of Checkpoint Adaptation in Fusion-Positive Rhabdomyosarcoma. The project period is 05/17/2021-07/09/2021.
Jennifer Rothman, MD (Hematology-Oncology) received an award from Dova Pharmaceuticals in the amount of $151,621 for an award entitled, A Phase 3b, Multi-center Randomized, Double0blind, Placebo-controlled, Paralle-group Trial with an Open-label Extension Phase to Evaluate the Efficacy and Safety of Avatrombopag for the Treatment of Thrombocytopenia in Pediatric Subjects with Immune. The project period is 03/18/2021-05/15/2025.
Laura Schanberg, MD (Rheumatology) received a four year extension from Childhood Arthritis & Rheumatology Research Alliance in the amount of $22,992,929 for an amendment entitled, DCRI CARRA Registry (4 year extension). The extension project period is 01/01/2021-04/30/2027.
Kanecia Zimmerman, MD (Critical Care) and Danny Benjamin Jr, MD, PhD, MPH (Infectious Diseases) received an award from the National Institutes of Health/NICHHD in the amount of $3,004,526 for an award entitled, SARS-CoV-2 Screening and Diagnostic Testing for Return to K-12 Schools. The project period is 04/15/2021-03/31/2022.
May 2021
Michael Cohen-Wolkowiez, MD, PhD (Infectious Diseases) received an award from the National Institutes of Health/NICHD in the amount of $920,200 for an award entitled Duke-UNC Collaborative Pediatric Clinical Pharmacology Postdoctoral Training Program. The project period is 05/01/2021-04/30/2026.
Neil Surana, MD, PhD (Infectious Diseases) and Teresa McDonald (Graduate Student) received an award from the National Science Foundation in the amount of $138,000 for an award entitled NSF Graduate Research Fellowship Award. The project period is 09/01/2021-08/31/2024.
Dwight Koeberl, MD, PhD (Medical Genetics) received an award from Lysoway Therapeutics in the amount of $47,786 for an award entitled Lysoway GSD 1a Research. The project period is 04/01/2021-03/31/2022.
Sierra Atwater (Medical Student) and Debra Lugo, MD (Infectious Diseases) received an award from the American Society of Hematology in the amount of $36,000 for an award entitled Optimizing Clostridium Difficile Diagnoses in High-Risk Hospitalized Pediatric Patients with Hematologic Malignancies or Undergoing, Hematopoietic Stem Cell Transplantation. The project period is 07/01/2021-06/30/2022.
William Steinbach, MD and Praveen Juvvadi, PhD (Infectious Diseases) received an award from the National Institutes of Health/NIAID in the amount of $$442,750 for an award entitled Calcineurin Regulatory Network Control of Aspergillus Fumigatus Hyphal Septation. The project period is 06/01/2021-05/31/2023.
Jessica Sun, MD (Hematology-Oncology) received an award from Actuate Therapeutics in the amount of $71,085 for an award entitled A Phase 1 study of 9-ING-41, a Glycogen Synthase Kinase-3 Beta (GSK-3b) inhibitor. The project period is 04/28/2021-04/30/2025.
Muhammad Zafar, MBBS (Neurology) received an award from UCB Biopharma in the amount of $112,923 for an award entitled An open-label, long-term safety and tolerability study of bivaracetam as adjunctive treatment in pediatric study participants with epilepsy. The project period is 05/12/2021-01/31/2023.
June 2021
Gregory Crawford, PhD (Medical Genetics), J.H. Pate Skene (Neurobiology), and Jason Stein, PhD (Genetics), received an award from the National Institutes of Health/NIMH in the amount of $770,618 for a project entitled, Genomics, Variation, and Evolution of Cerebellar Circuits Linked to Higher Cognitive Function in Humans. The project period is 07/01/2021-06/30/2023.
Elizabeth Erickson, MD (Primary Care), received an award from Reach Out and Read Carolinas in the amount of $112,200 for a project entitled, Reach Out and Read Career Development Award. The project period is 07/01/2021-06/30/2022.
Rachel Greenberg, MD (Neonatology), received an award from New York University School of Medicine/NHLBI in the amount of $14,350 for a project entitled, Post-Acute Sequelae of SARS-COV-2 Infection Initiative Phase 1. The project period is 06/09/2021-07/08/2021.
Corinne Linardic, MD, PhD (Hemaology-Oncology), received an award from Rally Foundation in the amount of $100,000 for a project entitled, Targeting CDK8 in Fusion-Positive Rhabdomyosarcoma. The project period is 07/01/2021-06/30/2023.
Laura Schanberg, MD (Rheumatology), received an award from CARRA/Bristol Myers Squibb in the amount of $183,709 for a project entitled, COVID Seropositive Conversion in Abatacept and Control Children in LIMIT-JIA. The project period is 06/07/2021-06/07/2025.
Emmanuel Walter, MD, MPH (Infectious Diseases), received an award from Pfizer in the amount of $263,130 for a project entitled, A Phase 3 Master Protocol to Evaluate Additional Dose(s) of BNT162B2 in Healthy Individuals Previously Vaccinated with BNT162B2. The project period is 06/09/2021-06/08/2023.
July 2021
Michael Deel, MD (Hematology-Oncology) received an award from National Pediatric Cancer Foundation, Inc. in the amount of $50,000 for a project entitled Preclinical Studies of NUAK Kinase Inhibitors in Fusion-Positive Rhabdomyosarcoma. The project period is 07/01/2021-06/30/2022.
Nancy McGreal, MD (Gastroenterology, Hepatology and Nutrition) received an award from Pfizer Inc. in the amount of $87,234 for a project entitled Open Label Induction and Maintenance Study of Oral CP-690,550 (Tofacitinib) in Children with Moderately to Severely Active Ulcerative Colitis. The project period is 05/24/2021-01/31/2025.
Jeffrey Russ, PhD (Neurology) received an award from Kennedy Krieger Institute in the amount of $407,614 for a project entitled Child Neurologist Career Development Program. The project period is 07/01/2021-06/30/2024.
Laura Schanberg, MD (Rheumatology) received an award from CARRA/Bristol Myers Squibb Foundation in the amount of $45,058 for a project entitled Sample collection to Predict Response to Abatacept in Limit-JIA. The project period is 07/26/2021-07/26/2024.
Vandana Shashi, MBBS, MD (Medical Genetics) and David Goldstein, PhD (Columbia) received a supplemental award from the National Institute of Health/NHGRI in the amount of $149,897 for a project entitled An Integrated and Diverse Genomic Medicine Program for Undiagnosed Diseases. The project period is 07/01/2021-06/30/2022.
Sarah Young, PhD (Medical Genetics) received an award from Maze Therapeutics in the amount of $8,545 for a project entitled Urinary GLC4 as a Marker of Glycogen Synthesis. The project period is 07/13/2021-12/31/2021.
Muhammad Zafar, MBBS (Neurology) received an award from Medicure International Inc. in the amount of $71,979 for a project entitled Study of Oral Pyridoxal 5’-Phosphate for the Treatment of Patients with PNPO Deficiency. The project period is 06/29/2021-06/30/2022.
August 2021
Deeksha Bali (Medical Genetics) received an award from JCR Pharmaceuticals Co., Ltd. In the amount of $89,882 for a project entitled, Method Development and Data Validation for MPS II-Clinical Study. The project period is 08/20/2021-07/31/2022.
Pinar Gumus Balikcioglu (Endocrinology) received a supplemental award from the National Institutes of Health/NIDDK in the amount of $93,946 for a project entitled, Serotonin as a Novel Biomarker for Progression to Type 2 Diabetes in Obese Adolescents. The project period is 09/01/2021-02/28/2023.
Christoph Hornik (Critical Care Medicine) received an award from the National Institutes of Health/NICHD in the amount of $794,942 for a project entitled, Collaborative Pediatric Critical Care Research Network-Clinical Site. The project period is 08/18/2021-07/31/2026.
Priya Kishnani (Medical Genetics) and Rebecca Gibson (MSTP/MGM Graduate Student) received an award from the National Institutes of Health/NICHD in the amount of $127,605 for a project entitled, Liver-Directed AAV Gene Therapy for PHKG2-Glcogen Storage Disease lX (GSD lXy2). The project period is 09/01/2021-08/31/2024.
Dwight Koeberl (Medical Genetics) received an award from the National Institutes of Health/NIAMSD in the amount of $3,365,536 for a project entitled, Stable Therapy in Pompe Disease Through Genome Editing. The project period is 08/01/2021-07/31/2026.
Neil Surana (Infectious Diseases) and Zeni Elizia Ramirez (MGM Graduate Student) received an award from the National Institutes of Health/Health/NIAID in the amount of $115,221 for a project entitled, Characterizing and Exploiting Ruminococcus Gnavus Mediated Induction of Antimicrobial Peptides. The project period is 09/01/2021-08/31/2024.
September 2021
Stephen Balevic (Rheumatology) received a new award from Childhood Arthritis & Rheumatology Research Alliance, Inc. in the amount of $37,523 for a project entitled, CARRA Registry Assistant Scientific Director. The project period is 09/01/2021-08/31/2023.
Mara Becker (Rheumatology) received a new award from National Institutes of Health/NICHD in the amount of $1,500,903 for a project entitled, PTN 2.0 TO 6 Clinical Pharmacokinetics & Safety Trials in Down Syndrome Extension. The project period 09/12/2019-06/30/2025.
Danny Benjamin (Infectious Diseases), Kanecia Zimmerman (Critical Care Medicine) and Rachel Greenberg (Neonatology) received a new (task order) award from the National Institutes (NICHD) in the amount of $849,525 for a project entitled, Pediatric Trials Network 2.0 Task Order #1_Core Function Activities Award Period #4 Option 3. The project period is 06/04/2021-06/03/2022.
Danny Benjamin (Infectious Diseases), Kanecia Zimmerman (Critical Care Medicine) and Rachel Greenberg (Neonatology) received a new (task order) award from the National Institutes (NICHD) in the amount of $359,911 for a project entitled, Pediatric Trials Network 2.0 Task Order #1_Core Function Activities Supplement Award Period #4 Option 3.1. The project period is 06/01/2021-05/31/2022.
Micheal Cohen-Wolkowiez (Infectious Diseases) received a supplemental award from the National Institutes of Health/NIMHD in the amount of $5,500,000 for a project entitled, RADx-UP SAY YES COVID Test Study. The project period is 08/23/2021-06/30/2022.
Areeg El-Gharbawy (Medical Genetics) received a new award from UltraGenyx Pharmaceutical in the amount of $985,456 for a project entitled, A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of Adeno-associated Virus Serotype 8-mediated GeneTransfer of Glucose-6-phosphatase in Patients with Glycogen Storage Disease Type Ia. The project period is 09/03/2021-09/30/2024.
Genevieve Fouda (Infectious Diseases), Matthew Kelly (Infectious Diseases) and Sallie Permar (Infectious Diseases, Weill Cornell Medicine) received a new award from the National Institutes of Health/NIAID in the amount of $3,996,243 for a project entitled, Early Life B Cell Responses and Inflammation Following SARS-CoV-2 Infection. The project period is 09/17/2021-08/31/2026.
Christoph Hornik (Critical Care Medicine) and Danny Benjamin (Infectious Diseases) received a new award from the National Institutes of Health/NICHD in the amount of $2,089,053 for a project entitled, Defining the Safety and Efficacy of Posterior Tibial Nerve Stimulation in Children. (Pediatric Trials Network 2.0 TO #10 - POSITRON-C). The project period is 9/13/2021 – 9/12/2024.
Andrew Landstrom (Cardiology) received a new award from University of British Columbia in the amount of $150 (per patient enrolled) for a project entitled, Physical Activity in Catecholaminergic Polymorphic Ventricular Tachycardia. The project period is 09/20/2021-06/30/2022.
David Ming (Hospital Medicine) received a new award from Agency of Healthcare Research and Quality in the amount of $299,999 for a project entitled, Feasibility Study of a Mobile Digital Personal Health Record for Family-Centered Care Coordination for Children and Youth with Special Healthcare Needs. The project period is 09/30/2021-09/29/2023.
Ann Reed (Rheumatology) received a new award from New York University in the amount of $9,000 for a project entitled, TFH Cells in Human Myositis. The project period is 04/05/2021-03/31/2022.
P. Brian Smith (Neonatology) and Rachel Greenberg (Neonatology) received a new supplemental award from National Institutes of Health/NICHD for a project entitled, ECHO Administrative Supplement – Neonatal Opioid Trials. The project period is 09/01/2021-08/31/2022.
William Steinbach (Infectious Diseases), Janet Englund (Infectious Diseases and Virology-Seattle Children's), Betsy Herold (Infectious Diseases-Albert Einstein College of Medicine) and Elaine Tuomanen (Infectious Diseases-St. Jude Children's Research Hospital) received a new award from the National Institutes of Health/NIAID in the amount of $4,126,972 for a project entitled, Multi-Center Evaluation of the Threat of Established and Emerging Respiratory Viral Infections in Pediatric Transplant Recipients. The project period is 09/17/2021-08/31/2026.
Kanecia Zimmerman (Critical Care Medicine) and Danny Benjamin (Infectious Diseases) received a new award from the National Institutes of Health/NICHD in the amount of $3,953,589 for a project entitled, Pharmaceuticals (PK) and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants (Pediatric Trials Network 2.0 TO # 11 - CUDDLE 2.0). The project period is 9/23/2021 – 9/22/2024.