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Phillip Brian Smith, MD

Samuel L. Katz Professor of Pediatrics
Professor of Pediatrics
Chief, Division of Quantitative Sciences, Pediatrics
Member in the Duke Clinical Research Institute
Campus mail: 800 W. Morgan St Box 17969, Dc 756, Durham, NC 27701
Phone: (919) 668-8951
Email address: brian.smith@duke.edu

Dr. Smith completed his residency in pediatrics and a fellowship in neonatal medicine at Duke University Medical Center in 2004 and 2007, respectively. He completed an MHS in clinical research from Duke University in 2006 and an MPH in biostatistics from the University of North Carolina at Chapel Hill in 2009. He research is focused on pediatric drug safety, neonatal pharmacology, and the epidemiology of neonatal infections. He is the chief of the Division of Quantitative Sciences in the Department of Pediatrics at Duke University Medical Center. Dr. Smith is or has been the protocol chair for more than 10 studies of drugs in infants and children. He is the Principal Investigator for the Environmental Influences on Child Health Outcomes (ECHO) Coordinating Center.

Education and Training

  • Fellowship in Neonatal-Perinatal Medicine, Pediatrics, Duke University, 2004 - 2007
  • Pediatric Internship & Residency, Pediatrics, Duke University, 2001 - 2004
  • M.P.H., University of North Carolina at Chapel Hill, 2009
  • M.H.S., Duke University School of Medicine, 2006
  • M.D., Mercer University, 2001

Selected Grants and Awards

Publications

Rivera-Chaparro, ND, Ericson, J, Wu, H, Smith, PB, Clark, RH, Benjamin, DK, Cohen-Wolkowiez, M, and Greenberg, RG. "Safety, Effectiveness and Exposure-response of Micafungin in Infants: Application of an Established Pharmacokinetics Model to Electronic Health Records." The Pediatric Infectious Disease Journal 38, no. 2 (February 2019): e26-e28.

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Bidegain, M, Herrera, TI, Smith, PB, and Cotten, CM. "Correspondence regarding "Outcomes of preterm infants treated with hypothermia for hypoxic-ischemic encephalopathy"." Early Human Development 128 (January 2019): 104-null. (Letter)

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Taylor, G, Jackson, W, Hornik, CP, Koss, A, Mantena, S, Homsley, K, Gattis, B, Kudumu-Clavell, M, Clark, R, Smith, PB, and Laughon, MM. "Surfactant Administration in Preterm Infants: Drug Development Opportunities." The Journal of Pediatrics (December 21, 2018).

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Greene, NH, Greenberg, RG, O'Brien, SM, Kemper, AR, Miranda, ML, Clark, RH, and Smith, PB. "Variation in Gastrostomy Tube Placement in Premature Infants in the United States." American Journal of Perinatology (December 21, 2018).

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Greenberg, RG, Gayam, S, Savage, D, Tong, A, Gorham, D, Sholomon, A, Clark, RH, Benjamin, DK, Laughon, M, Smith, PB, and Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee, . "Furosemide Exposure and Prevention of Bronchopulmonary Dysplasia in Premature Infants." The Journal of Pediatrics (December 20, 2018).

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Ku, LC, Simmons, C, Smith, PB, Greenberg, RG, Fisher, K, Hornik, CD, Cotten, CM, Goldberg, RN, and Bidegain, M. "Intranasal midazolam and fentanyl for procedural sedation and analgesia in infants in the neonatal intensive care unit." Journal of Neonatal Perinatal Medicine (December 11, 2018).

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Autmizguine, J, Smith, PB, Prather, K, Bendel, C, Natarajan, G, Bidegain, M, Kaufman, DA, Burchfield, DJ, Ross, AS, Pandit, P, Schell, WA, Gao, J, Benjamin, DK, and Fluconazole Prophylaxis Study Team, . "Effect of fluconazole prophylaxis on Candida fluconazole susceptibility in premature infants." The Journal of Antimicrobial Chemotherapy 73, no. 12 (December 2018): 3482-3487.

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Puia-Dumitrescu, M, Bretzius, OM, Brown, N, Fitz-Henley, JA, Ssengonzi, R, Wechsler, CS, Gray, KD, Benjamin, DK, Smith, PB, Clark, RH, Gonzalez, D, and Hornik, CP. "Evaluation of Gentamicin Exposure in the Neonatal Intensive Care Unit and Hearing Function at Discharge." The Journal of Pediatrics 203 (December 2018): 131-136.

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Tolia, VN, Murthy, K, Bennett, MM, Greenberg, RG, Benjamin, DK, Smith, PB, and Clark, RH. "Morphine vs Methadone Treatment for Infants with Neonatal Abstinence Syndrome." The Journal of Pediatrics 203 (December 2018): 185-189.

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Greenberg, RG, Smith, PB, Bose, C, Clark, RH, Cotten, CM, and DeRienzo, C. "National Survey of Neonatal Intensive Care Unit Medication Safety Practices." American Journal of Perinatology 35, no. 14 (December 2018): 1419-1422.

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