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Phillip Brian Smith, MD

Samuel L. Katz Professor of Pediatrics
Professor of Pediatrics
Chief, Division of Quantitative Sciences, Pediatrics
Member in the Duke Clinical Research Institute
Campus mail: 800 W. Morgan St Box 17969, Dc 756, Durham, NC 27701
Phone: (919) 668-8951
Email address: brian.smith@duke.edu

Dr. Smith completed his residency in pediatrics and a fellowship in neonatal medicine at Duke University Medical Center in 2004 and 2007, respectively. He completed an MHS in clinical research from Duke University in 2006 and an MPH in biostatistics from the University of North Carolina at Chapel Hill in 2009. He research is focused on pediatric drug safety, neonatal pharmacology, and the epidemiology of neonatal infections. He is the chief of the Division of Quantitative Sciences in the Department of Pediatrics at Duke University Medical Center. Dr. Smith is or has been the protocol chair for more than 10 studies of drugs in infants and children. He is the Principal Investigator for the Environmental Influences on Child Health Outcomes (ECHO) Coordinating Center.

Education and Training

  • Fellowship in Neonatal-Perinatal Medicine, Pediatrics, Duke University, 2004 - 2007
  • Pediatric Internship & Residency, Pediatrics, Duke University, 2001 - 2004
  • M.P.H., University of North Carolina at Chapel Hill, 2009
  • M.H.S., Duke University School of Medicine, 2006
  • M.D., Mercer University, 2001

Selected Grants and Awards

Publications

Puia-Dumitrescu, M, Benjamin, DK, Smith, PB, Greenberg, RG, Abuzaid, N, Andrews, W, Chellani, K, Gupta, A, Price, D, Williams, C, Malcolm, WF, Clark, RH, and Zimmerman, KO. "Impact of Gastrostomy Tube Placement on Short-Term Weight Gain in Hospitalized Premature Infants." Jpen. Journal of Parenteral and Enteral Nutrition (March 25, 2019).

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Smith, PB, Cotten, CM, Hudak, ML, Sullivan, JE, Poindexter, BB, Cohen-Wolkowiez, M, Boakye-Agyeman, F, Lewandowski, A, Anand, R, Benjamin, DK, Laughon, MM, and Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee, . "Rifampin Pharmacokinetics and Safety in Preterm and Term Infants." Antimicrobial Agents and Chemotherapy (March 25, 2019).

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Bartle, RM, Miller, AG, Diez, AJ, Smith, PB, Gentile, MA, and Puia-Dumitrescu, M. "Evaluating Endotracheal Tube Depth in Infants Weighing Less Than 1 Kilogram." Respiratory Care 64, no. 3 (March 2019): 243-247.

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Watt, KM, Hornik, CP, Balevic, SJ, Mundakel, G, Cotten, CM, Harper, B, Benjamin, DK, Anand, R, Laughon, M, Smith, PB, Cohen-Wolkowiez, M, and Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee, . "Pharmacokinetics of ticarcillin-clavulanate in premature infants." British Journal of Clinical Pharmacology (February 2, 2019).

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Rivera-Chaparro, ND, Ericson, J, Wu, H, Smith, PB, Clark, RH, Benjamin, DK, Cohen-Wolkowiez, M, and Greenberg, RG. "Safety, Effectiveness and Exposure-response of Micafungin in Infants: Application of an Established Pharmacokinetics Model to Electronic Health Records." The Pediatric Infectious Disease Journal 38, no. 2 (February 2019): e26-e28.

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Thompson, EJ, Perez, K, Hornik, CP, Smith, PB, Clark, RH, Laughon, M, and Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee, . "Sildenafil Exposure in the Neonatal Intensive Care Unit." American Journal of Perinatology 36, no. 3 (February 2019): 262-267.

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Greenberg, RG, Chowdhury, D, Hansen, NI, Smith, PB, Stoll, BJ, Sánchez, PJ, Das, A, Puopolo, KM, Mukhopadhyay, S, Higgins, RD, Cotten, CM, and Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, . "Prolonged duration of early antibiotic therapy in extremely premature infants." Pediatric Research (January 22, 2019).

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Bidegain, M, Herrera, TI, Smith, PB, and Cotten, CM. "Correspondence regarding "Outcomes of preterm infants treated with hypothermia for hypoxic-ischemic encephalopathy"." Early Human Development 128 (January 2019): 104-null. (Letter)

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Taylor, G, Jackson, W, Hornik, CP, Koss, A, Mantena, S, Homsley, K, Gattis, B, Kudumu-Clavell, M, Clark, R, Smith, PB, and Laughon, MM. "Surfactant Administration in Preterm Infants: Drug Development Opportunities." The Journal of Pediatrics (December 21, 2018).

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Greene, NH, Greenberg, RG, O'Brien, SM, Kemper, AR, Miranda, ML, Clark, RH, and Smith, PB. "Variation in Gastrostomy Tube Placement in Premature Infants in the United States." American Journal of Perinatology (December 21, 2018).

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