Skip to main content

Search form

You are here

Phillip Brian Smith, MD

Samuel L. Katz Distinguished Professor of Pediatrics
Professor of Pediatrics
Member in the Duke Clinical Research Institute
Campus mail: 800 W. Morgan St Box 17969, DC 756, Durham, NC 27701
Phone: (919) 668-8951
Email address: brian.smith@duke.edu

Dr. Smith completed his residency in pediatrics and a fellowship in neonatal medicine at Duke University Medical Center in 2004 and 2007, respectively. He completed an MHS in clinical research from Duke University in 2006 and an MPH in biostatistics from the University of North Carolina at Chapel Hill in 2009. He research is focused on pediatric drug safety, neonatal pharmacology, and the epidemiology of neonatal infections. He is the chief of the Division of Quantitative Sciences in the Department of Pediatrics at Duke University Medical Center. Dr. Smith is or has been the protocol chair for more than 10 studies of drugs in infants and children. He is the Principal Investigator for the Environmental Influences on Child Health Outcomes (ECHO) Coordinating Center.

Education and Training

  • Fellowship in Neonatal-Perinatal Medicine, Pediatrics, Duke University, 2004 - 2007
  • Pediatric Internship & Residency, Pediatrics, Duke University, 2001 - 2004
  • M.P.H., University of North Carolina - Chapel Hill, 2009
  • M.H.S., Duke University School of Medicine, 2006
  • M.D., Mercer University, 2001

Selected Grants and Awards

Publications

Singh, Anisha, Howard W. Francis, P Brian Smith, Reese H. Clark, and Rachel G. Greenberg. “Association between Hyperbilirubinemia and Hearing Screen Failure in the Neonatal Intensive Care Unit in Infants Born Preterm.” J Pediatr, January 19, 2021. https://doi.org/10.1016/j.jpeds.2020.12.059.

Full Text

Polcwiartek, Laura Bech, P Brian Smith, Daniel K. Benjamin, Kanecia Zimmerman, Alycia Love, Lance Tiu, Sylvia Murray, et al. “Early-onset sepsis in term infants admitted to neonatal intensive care units (2011-2016).” J Perinatol 41, no. 1 (January 2021): 157–63. https://doi.org/10.1038/s41372-020-00860-3.

Full Text

Young, Leslie W., Zhuopei Hu, Robert D. Annett, Abhik Das, Janell F. Fuller, Rosemary D. Higgins, Barry M. Lester, et al. “Site-Level Variation in the Characteristics and Care of Infants With Neonatal Opioid Withdrawal.” Pediatrics 147, no. 1 (January 2021). https://doi.org/10.1542/peds.2020-008839.

Full Text

Miller, Laura E., Chris DeRienzo, P Brian Smith, Carl Bose, Reese H. Clark, C Michael Cotten, Daniel K. Benjamin, Chi D. Hornik, and Rachel G. Greenberg. “Association between neonatal intensive care unit medication safety practices, adverse events, and death.” J Perinatol, October 8, 2020. https://doi.org/10.1038/s41372-020-00857-y.

Full Text

Maharaj, Anil R., Huali Wu, Christoph P. Hornik, Stephen J. Balevic, Chi D. Hornik, P Brian Smith, Daniel Gonzalez, et al. “Simulated Assessment of Pharmacokinetically Guided Dosing for Investigational Treatments of Pediatric Patients With Coronavirus Disease 2019.” Jama Pediatr 174, no. 10 (October 1, 2020): e202422. https://doi.org/10.1001/jamapediatrics.2020.2422.

Full Text

Commander, Sarah Jane, Jamie Gao, Erin K. Zinkhan, Gloria Heresi, Sherry E. Courtney, Adrian P. Lavery, Paula Delmore, et al. “Safety of Metronidazole in Late Pre-term and Term Infants with Complicated Intra-abdominal Infections.” Pediatr Infect Dis J 39, no. 9 (September 2020): e245–48. https://doi.org/10.1097/INF.0000000000002698.

Full Text

Stark, Ashley, Julie Childers, Morgan England, Reese H. Clark, Matthew Laughon, Michael Cohen-Wolkowiez, Daniel K. Benjamin, P Brian Smith, Kelly Wade, and Rachel G. Greenberg. “Dosing of Antimicrobials in the Neonatal Intensive Care Unit: Does Clinical Practice Reflect Pharmacokinetics-based Recommendations?” Pediatr Infect Dis J 39, no. 8 (August 2020): 713–17. https://doi.org/10.1097/INF.0000000000002657.

Full Text

Ericson, Jessica E., John McGuire, Marian G. Michaels, Adam Schwarz, Robert Frenck, Jaime G. Deville, Swati Agarwal, et al. “Hospital-acquired Pneumonia and Ventilator-associated Pneumonia in Children: A Prospective Natural History and Case-Control Study.” Pediatr Infect Dis J 39, no. 8 (August 2020): 658–64. https://doi.org/10.1097/INF.0000000000002642.

Full Text

Ericson, Jessica E., Christoph P. Hornik, Rachel G. Greenberg, Reese H. Clark, Adriana H. Tremoulet, Jennifer Le, Michael Cohen-Wolkowiez, P Brian Smith, Daniel K. Benjamin, and Daniel K. Best Pharmaceuticals for Children Act – Pediatric Trials Network. “Paradoxical Antibiotic Effect of Ampicillin: Use of a Population Pharmacokinetic Model to Evaluate a Clinical Correlate of the Eagle Effect in Infants With Bacteremia.” Pediatr Infect Dis J 39, no. 8 (August 2020): 725–29. https://doi.org/10.1097/INF.0000000000002663.

Full Text

Puia-Dumitrescu, Mihai, Daniel K. Benjamin, P Brian Smith, Rachel G. Greenberg, Nada Abuzaid, Winsome Andrews, Kris Chellani, et al. “Impact of Gastrostomy Tube Placement on Short-Term Weight Gain in Hospitalized Premature Infants.” Jpen J Parenter Enteral Nutr 44, no. 2 (February 2020): 355–60. https://doi.org/10.1002/jpen.1539.

Full Text

Pages