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Michael Anthony Moody, MD

Associate Professor of Pediatrics
Associate Professor in the Department of Immunology
Member of the Duke Human Vaccine Institute
Campus mail: 2 Genome Ct, MSRB II Room 3007, Durham, NC 27710
Phone: (919) 668-2551
Email address: tony.moody@duke.edu

Tony Moody, MD is an Associate Professor in the Department of Pediatrics, Division of Infectious Diseases and the Department of Immunology at Duke University Medical Center. Research in the Moody lab is focused on understanding the B cell responses during infection, vaccination, and disease. The lab has become a resource for human phenotyping, flow characterization, staining and analysis at the Duke Human Vaccine Institute (DHVI). The Moody lab is currently funded to study influenza, syphilis, HIV-1, and emerging infectious diseases.

Dr. Moody is the director of the Duke CIVICs Vaccine Center (DCVC) at (DHVI) and co-director of the Centers for Research of Emerging Infectious Disease Coordinating Center (CREID-CC). Dr. Moody is co-PI of a U19 program to develop a syphilis vaccine; this program is led by Dr. Justin Radolf at the University of Connecticut. Dr. Moody is also the director of the DHVI Accessioning Unit, a biorepository that provides support for work occurring at DHVI and with its many collaborators around the world by providing processing, shipping, and inventory support for a wide array of projects.

Dr. Moody and his team are involved in many networks studying vaccine response including the Collaborative Influenza Vaccine Innovation Centers (CIVICs), HIV Vaccine Trials Network (HVTN) and the COVID-19 Prevention Network (CoVPN).

Education and Training

  • Fellowship, Pediatric Infectious Diseases, Pediatrics, Duke University, 2003 - 2006
  • Pediatric Chief Resident, Pediatrics, Emory University, 2002 - 2003
  • Pediatric Internship & Residency, Pediatrics, Emory University, 1999 - 2002
  • M.D., Duke University, 1999

Selected Grants and Awards

Publications

Alam, S Munir, Richard M. Scearce, Robert J. Parks, Kelly Plonk, Steven G. Plonk, Laura L. Sutherland, Miroslaw K. Gorny, et al. “Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection.” J Virol 82, no. 1 (January 2008): 115–25. https://doi.org/10.1128/JVI.00927-07.

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Lenfestey, RW, Smith, PB, Moody, MA, Clark, RH, Cotten, CM, Seed, PC, and Benjamin, DK. "Predictive value of cerebrospinal fluid parameters in neonates with intraventricular drainage devices." J Neurosurg 107, no. 3 Suppl (September 2007): 209-212.

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Garges, Harmony P., M Anthony Moody, C Michael Cotten, P Brian Smith, Kenneth F. Tiffany, Robert Lenfestey, Jennifer S. Li, Vance G. Fowler, and Daniel K. Benjamin. “Neonatal meningitis: what is the correlation among cerebrospinal fluid cultures, blood cultures, and cerebrospinal fluid parameters?” Pediatrics 117, no. 4 (April 2006): 1094–1100. https://doi.org/10.1542/peds.2005-1132.

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Smith, P. B., C. M. Cotten, H. P. Garges, K. F. Tiffany, R. W. Lenfestey, M. A. Moody, J. S. Li, and D. K. Benjamin. “A comparison of neonatal Gram-negative rod and Gram-positive cocci meningitis.” J Perinatol 26, no. 2 (February 2006): 111–14. https://doi.org/10.1038/sj.jp.7211438.

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Haynes, Barton F., M Anthony Moody, Laurent Verkoczy, Garnett Kelsoe, and S Munir Alam. “Antibody polyspecificity and neutralization of HIV-1: a hypothesis.” Hum Antibodies 14, no. 3–4 (2005): 59–67.

Scholars@Duke

Heeney, Matthew M., Susan M. Ormsbee, M Anthony Moody, Thad A. Howard, Carlos M. DeCastro, and Russell E. Ware. “Increased expression of anti-apoptosis genes in peripheral blood cells from patients with paroxysmal nocturnal hemoglobinuria.” Mol Genet Metab 78, no. 4 (April 2003): 291–94. https://doi.org/10.1016/s1096-7192(03)00047-7.

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Ware, R. E., S. M. Ormsbee, M. A. Moody, and T. A. Howard. “Overexpression of anti-apoptosis genes in association with resistance to apoptosis observed in bone marrow failure syndromes.” Blood 96, no. 11 (November 16, 2000): 526A-526A.

Scholars@Duke

Ware, R. E., S. M. Ormsbee, M. A. Moody, and T. A. Howard. “Overexpression of four anti-apoptotic genes in association with resistance to apoptosis observed in bone marrow failure syndromes.” Pediatric Research 47, no. 4 (April 1, 2000): 254A-254A.

Scholars@Duke

Vu, H. M., D. Myers, R. de Lorimier, T. J. Matthews, M. A. Moody, C. Heinly, J. V. Torres, B. F. Haynes, and L. Spicer. “Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120: relation to specificity of peptide-induced anti-HIV neutralizing antibodies.” J Virol 73, no. 1 (January 1999): 746–50. https://doi.org/10.1128/JVI.73.1.746-750.1999.

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Moody, M. A., T. A. Howard, and R. E. Ware. “Mechanisms of resistance to apoptosis in granulocytes of patients with paroxysmal nocturnal hemoglobinuria.” Blood 92, no. 10 (November 15, 1998): 6B-7B.

Scholars@Duke

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