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Michael Anthony Moody, MD

Associate Professor of Pediatrics
Associate Professor in the Department of Immunology
Member of the Duke Human Vaccine Institute
Campus mail: 2 Genome Ct, MSRB II Room 3007, Durham, NC 27710
Phone: (919) 668-2551
Email address: tony.moody@duke.edu

Tony Moody, MD is an Associate Professor in the Department of Pediatrics, Division of Infectious Diseases and the Department of Immunology at Duke University Medical Center. Research in the Moody lab is focused on understanding the B cell responses during infection, vaccination, and disease. The lab has become a resource for human phenotyping, flow characterization, staining and analysis at the Duke Human Vaccine Institute (DHVI). The Moody lab is currently funded to study influenza, syphilis, HIV-1, and emerging infectious diseases.

Dr. Moody is the director of the Duke CIVICs Vaccine Center (DCVC) at (DHVI) and co-director of the Centers for Research of Emerging Infectious Disease Coordinating Center (CREID-CC). Dr. Moody is co-PI of a U19 program to develop a syphilis vaccine; this program is led by Dr. Justin Radolf at the University of Connecticut. Dr. Moody is also the director of the DHVI Accessioning Unit, a biorepository that provides support for work occurring at DHVI and with its many collaborators around the world by providing processing, shipping, and inventory support for a wide array of projects.

Dr. Moody and his team are involved in many networks studying vaccine response including the Collaborative Influenza Vaccine Innovation Centers (CIVICs), HIV Vaccine Trials Network (HVTN) and the COVID-19 Prevention Network (CoVPN).

Education and Training

  • Fellowship, Pediatric Infectious Diseases, Pediatrics, Duke University, 2003 - 2006
  • Pediatric Chief Resident, Pediatrics, Emory University, 2002 - 2003
  • Pediatric Internship & Residency, Pediatrics, Emory University, 1999 - 2002
  • M.D., Duke University, 1999

Selected Grants and Awards

Publications

Liao, Hua-Xin, Marc C. Levesque, Ashleigh Nagel, Ashlyn Dixon, Ruijun Zhang, Emmanuel Walter, Robert Parks, et al. “High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies.” J Virol Methods 158, no. 1–2 (June 2009): 171–79. https://doi.org/10.1016/j.jviromet.2009.02.014.

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Bonsignori, M., K. Hwang, N. Vandergrift, M. A. Moody, and B. F. Haynes. “P04-01. Simultaneous enumeration of HIV-1 gp41 Env-specific IgG and IgM antibody-secreting cells with a multiplex B-cell fluorospot assay.” Retrovirology 6, no. Suppl 3 (January 2009): P29–P29. https://doi.org/10.1186/1742-4690-6-s3-p29.

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Holl, T. M., M. Kuraoka, D. Liao, L. Verkoczy, M. A. Moody, M. Alam, H. Liao, B. F. Haynes, and G. H. Kelsoe. “P04-44. Generation of antibody responses to HIV-1 membrane proximal external region (MPER) antigen.” Retrovirology 6, no. SUPPL. 3 (2009): P72.

Scholars@Duke

Bonsignori, M., M. A. Moody, R. J. Parks, T. M. Holl, G. Kelsoe, C. B. Hicks, N. Vandergrift, G. D. Tomaras, and B. F. Haynes. “P04-48. HIV-1 envelope induces memory B cell responses that correlate with plasma antibody levels after gp120 protein vaccination or chronic HIV-1 infection.” In Retrovirology, 6:P76–P76, 2009. https://doi.org/10.1186/1742-4690-6-s3-p76.

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Greenberg, Rachel G., P Brian Smith, C Michael Cotten, M Anthony Moody, Reese H. Clark, and Daniel K. Benjamin. “Traumatic lumbar punctures in neonates: test performance of the cerebrospinal fluid white blood cell count.” Pediatr Infect Dis J 27, no. 12 (December 2008): 1047–51. https://doi.org/10.1097/INF.0b013e31817e519b.

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Moody, M Anthony, and Barton F. Haynes. “Antigen-specific B cell detection reagents: use and quality control.” Cytometry A 73, no. 11 (November 2008): 1086–92. https://doi.org/10.1002/cyto.a.20599.

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Moody, M. A., M. K. Plonk, L. Fuller, H. Liao, S. Xia, M. S. Drinker, T. C. Gurley, et al. “Anti-lipid Human Monoclonal Antibodies Inhibit HIV-1 Infection of PBMC by Binding to Host Cells.” In Aids Research and Human Retroviruses, 24:13–13. MARY ANN LIEBERT INC, 2008.

Scholars@Duke

Holl, M. T., M. Kuraoka, D. Liao, L. Verkoczy, M. A. Moody, S. M. Alam, B. Haynes, and G. Kelsoe. “Generation of Robust Antibody Responses to HIV-1 Membrane Proximal External Region (MPER) Antigens.” In Aids Research and Human Retroviruses, 24:24–25. MARY ANN LIEBERT INC, 2008.

Scholars@Duke

Roederer, Mario, and M Anthony Moody. “Polychromatic plots: graphical display of multidimensional data.” Cytometry A 73, no. 9 (September 2008): 868–74. https://doi.org/10.1002/cyto.a.20610.

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Gasper-Smith, Nancy, Deanna M. Crossman, John F. Whitesides, Nadia Mensali, Janet S. Ottinger, Steven G. Plonk, M Anthony Moody, et al. “Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design.” J Virol 82, no. 15 (August 2008): 7700–7710. https://doi.org/10.1128/JVI.00605-08.

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