Skip to main content

Michael Anthony Moody, MD

Associate Professor of Pediatrics
Associate Professor in the Department of Immunology
Member of the Duke Human Vaccine Institute
Campus mail: 2 Genome Ct, MSRB II Room 3007, Durham, NC 27710
Phone: (919) 668-2551
Email address: tony.moody@duke.edu

Tony Moody, MD is an Associate Professor in the Department of Pediatrics, Division of Infectious Diseases and the Department of Immunology at Duke University Medical Center. Research in the Moody lab is focused on understanding the B cell responses during infection, vaccination, and disease. The lab has become a resource for human phenotyping, flow characterization, staining and analysis at the Duke Human Vaccine Institute (DHVI). The Moody lab is currently funded to study influenza, syphilis, HIV-1, and emerging infectious diseases.

Dr. Moody is the director of the Duke CIVICs Vaccine Center (DCVC) at (DHVI) and co-director of the Centers for Research of Emerging Infectious Disease Coordinating Center (CREID-CC). Dr. Moody is co-PI of a U19 program to develop a syphilis vaccine; this program is led by Dr. Justin Radolf at the University of Connecticut. Dr. Moody is also the director of the DHVI Accessioning Unit, a biorepository that provides support for work occurring at DHVI and with its many collaborators around the world by providing processing, shipping, and inventory support for a wide array of projects.

Dr. Moody and his team are involved in many networks studying vaccine response including the Collaborative Influenza Vaccine Innovation Centers (CIVICs), HIV Vaccine Trials Network (HVTN) and the COVID-19 Prevention Network (CoVPN).

Education and Training

  • Fellowship, Pediatric Infectious Diseases, Pediatrics, Duke University, 2003 - 2006
  • Pediatric Chief Resident, Pediatrics, Emory University, 2002 - 2003
  • Pediatric Internship & Residency, Pediatrics, Emory University, 1999 - 2002
  • M.D., Duke University, 1999

Selected Grants and Awards

Publications

Liao, H., X. Chen, S. Munshaw, R. Zhang, D. Marshall, J. Whitesides, A. Foulger, et al. “Early plasma B cell responses to transmitted HIV-1 are directed to envelope gp41 and originate by the activation of mutated B cell clones.” In Aids Research and Human Retroviruses, 26:A23–A23. MARY ANN LIEBERT INC, 2010.

Scholars@Duke

Moody, M. A., J. D. Amos, T. C. Gurley, M. S. Drinker, K. D. Luney, D. J. Marshall, J. F. Whitesides, et al. “Isolation of Human Monoclonal Antibodies from HIV-Uninfected Subjects Immunized with gp120/NefTat/AS01B by Dual-Color Antigen-Specific B Cell Sorting.” In Aids Research and Human Retroviruses, 26:A15–A15. MARY ANN LIEBERT INC, 2010.

Scholars@Duke

Moody, M Anthony, Hua-Xin Liao, S Munir Alam, Richard M. Scearce, M Kelly Plonk, Daniel M. Kozink, Mark S. Drinker, et al. “Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines.” J Exp Med 207, no. 4 (April 12, 2010): 763–76. https://doi.org/10.1084/jem.20091281.

Full Text

Robinson, Angela Byun, Esi Morgan DeWitt, Laura Eve Schanberg, and M Anthony Moody. “Necrotizing fasciitis caused by Haemophilus influenzae type E in a 17-year-old girl with systemic lupus erythematosus.” J Clin Rheumatol 16, no. 1 (January 2010): 49–50. https://doi.org/10.1097/RHU.0b013e3181c7e095.

Full Text

Gao, Feng, Richard M. Scearce, S Munir Alam, Bhavna Hora, Shimao Xia, Julie E. Hohm, Robert J. Parks, et al. “Cross-reactive monoclonal antibodies to multiple HIV-1 subtype and SIVcpz envelope glycoproteins.” Virology 394, no. 1 (November 10, 2009): 91–98. https://doi.org/10.1016/j.virol.2009.07.041.

Full Text

Liao, L., X. Chen, A. Dixon, S. Munshaw, M. Moody, R. Zhang, A. Nagel, et al. “P04-45. Characterization of the plasma cell repertoire in acute HIV-1 infection (AHI).” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-P73.

Full Text

Munshaw, S., H. Liao, A. Dixon, X. Chen, A. Nagel, K. Derosa, R. Parks, et al. “S021-04 OA. A large-scale analysis of immunoglobulin sequences derived from plasmablasts/plasma cells in acute HIV-1 infection subjects.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-O4.

Full Text

Verkoczy, Laurent, M Anthony Moody, T Matt Holl, Hilary Bouton-Verville, Richard M. Scearce, Jennifer Hutchinson, S Munir Alam, Garnett Kelsoe, and Barton F. Haynes. “Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region.” Plos One 4, no. 10 (October 6, 2009): e7215. https://doi.org/10.1371/journal.pone.0007215.

Full Text

Bonsignori, Mattia, M Anthony Moody, Robert J. Parks, T Matt Holl, Garnett Kelsoe, Charles B. Hicks, Nathan Vandergrift, Georgia D. Tomaras, and Barton F. Haynes. “HIV-1 envelope induces memory B cell responses that correlate with plasma antibody levels after envelope gp120 protein vaccination or HIV-1 infection.” J Immunol 183, no. 4 (August 15, 2009): 2708–17. https://doi.org/10.4049/jimmunol.0901068.

Full Text

Levesque, Marc C., M Anthony Moody, Kwan-Ki Hwang, Dawn J. Marshall, John F. Whitesides, Joshua D. Amos, Thaddeus C. Gurley, et al. “Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection.” Plos Med 6, no. 7 (July 7, 2009): e1000107. https://doi.org/10.1371/journal.pmed.1000107.

Full Text

Pages