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Michael Anthony Moody, MD

Associate Professor of Pediatrics
Associate Professor in the Department of Immunology
Member of the Duke Human Vaccine Institute
Campus mail: 2 Genome Ct, MSRB II Room 3007, Durham, NC 27710
Phone: (919) 668-2551
Email address: tony.moody@duke.edu

Tony Moody, MD is an Associate Professor in the Department of Pediatrics, Division of Infectious Diseases and the Department of Immunology at Duke University Medical Center. Research in the Moody lab is focused on understanding the B cell responses during infection, vaccination, and disease. The lab has become a resource for human phenotyping, flow characterization, staining and analysis at the Duke Human Vaccine Institute (DHVI). The Moody lab is currently funded to study influenza, syphilis, HIV-1, and emerging infectious diseases.

Dr. Moody is the director of the Duke CIVICs Vaccine Center (DCVC) at (DHVI) and co-director of the Centers for Research of Emerging Infectious Disease Coordinating Center (CREID-CC). Dr. Moody is co-PI of a U19 program to develop a syphilis vaccine; this program is led by Dr. Justin Radolf at the University of Connecticut. Dr. Moody is also the director of the DHVI Accessioning Unit, a biorepository that provides support for work occurring at DHVI and with its many collaborators around the world by providing processing, shipping, and inventory support for a wide array of projects.

Dr. Moody and his team are involved in many networks studying vaccine response including the Collaborative Influenza Vaccine Innovation Centers (CIVICs), HIV Vaccine Trials Network (HVTN) and the COVID-19 Prevention Network (CoVPN).

Education and Training

  • Fellowship, Pediatric Infectious Diseases, Pediatrics, Duke University, 2003 - 2006
  • Pediatric Chief Resident, Pediatrics, Emory University, 2002 - 2003
  • Pediatric Internship & Residency, Pediatrics, Emory University, 1999 - 2002
  • M.D., Duke University, 1999

Selected Grants and Awards

Publications

Bonsignori, M., J. Pollara, M. A. Moody, T. B. Kepler, X. Chen, T. C. Gurley, D. M. Kozink, et al. “Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial preferentially use the VH1 gene family.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p78.

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Moody, M., M. S. Drinker, T. C. Gurley, J. D. Amos, J. A. Eudailey, L. C. Armand, R. Parks, et al. “Isolation of a clonal lineage of IgA broadly neutralizing antibodies from a chronically infected Tanzanian subject.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o35.

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Trama, A. M., H. Liao, A. Foulger, D. J. Marshall, J. F. Whitesides, R. Parks, R. Meyerhoff, et al. “Lack of IgA envelope-reactive antibody producing cells in terminal ileum in early and chronic HIV-1 infection.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p201.

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Williams, W. B., K. Jones, A. Krambrink, D. Grove, P. Liu, N. L. Yates, M. A. Moody, et al. “Multiple antibody specificities (gp41, V1V2, and V3) elicited in the phase II multiclade (A, B, C) HIV-1 DNA prime, rAd5 boost vaccine trial.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o55.

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Amos, J. D., A. B. Wilks, G. G. Fouda, S. D. Smith, G. R. Overman, K. Beck, M. A. Moody, G. D. Tomaras, and S. R. Permar. “Strong SIV gp120-specific IgG/IgA responses in milk of African green monkeys may contribute to the rarity of postnatal transmission in this species.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p198.

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Pollara, J., M. Bonsignori, M. Moody, M. Alam, H. Liao, K. Hwang, J. Pickeral, et al. “Vaccine-induced ADCC-mediating antibodies target unique and overlapping envelope epitopes.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o39.

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Montefiori, David C., Chitraporn Karnasuta, Ying Huang, Hasan Ahmed, Peter Gilbert, Mark S. de Souza, Robert McLinden, et al. “Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials.” J Infect Dis 206, no. 3 (August 1, 2012): 431–41. https://doi.org/10.1093/infdis/jis367.

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Moody, M Anthony, Nicole L. Yates, Joshua D. Amos, Mark S. Drinker, Joshua A. Eudailey, Thaddeus C. Gurley, Dawn J. Marshall, et al. “HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages.” J Virol 86, no. 14 (July 2012): 7496–7507. https://doi.org/10.1128/JVI.00426-12.

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Thomas, Rasmi, Chloe L. Thio, Richard Apps, Ying Qi, Xiaojiang Gao, Darlene Marti, Judy L. Stein, et al. “A novel variant marking HLA-DP expression levels predicts recovery from hepatitis B virus infection.” J Virol 86, no. 12 (June 2012): 6979–85. https://doi.org/10.1128/JVI.00406-12.

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Su, Kuei-Ying, Laurie McWilliams, Xiaoe Liang, Serina Floyd, Joshua Amos, M. Moody, Masayuki Kuraoka, and Garnett Kelsoe. “CD27 expression patterns on human developing B cells in fetal and adult tissues.” In Journal of Immunology, Vol. 188. AMER ASSOC IMMUNOLOGISTS, 2012.

Scholars@Duke

Pages