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Genevieve Giny Fouda, MD, PhD

Associate Professor in Pediatrics
Assistant Research Professor in the Department of Molecular Genetics and Microbiology
Member of the Duke Human Vaccine Institute
Campus mail: DUMC Box 103020, Durham, NC 27710
Phone: (919) 681-0608
Email address: genevieve.fouda@duke.edu

Dr Fouda's research interest is in understanding infant immune responses in the setting of infection and vaccination. Her current work focuses on HIV mother to child transmission.

Education and Training

  • Ph.D., Georgetown University, 2006
  • M.D., University of Yaoundé I (Cameroon), 2002

Publications

Sacha, C. R., N. Vandergrift, T. L. Jeffries, E. McGuire, G. G. Fouda, B. Liebl, D. J. Marshall, et al. “Restricted isotype, distinct variable gene usage, and high rate of gp120 specificity of HIV-1 envelope-specific B cells in colostrum compared with those in blood of HIV-1-infected, lactating African women..” Mucosal Immunol 8, no. 2 (March 2015): 316–26. https://doi.org/10.1038/mi.2014.69.

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Fouda, Genevieve G., Coleen K. Cunningham, Elizabeth J. McFarland, William Borkowsky, Petronella Muresan, Justin Pollara, Lin Ye Song, et al. “Infant HIV type 1 gp120 vaccination elicits robust and durable anti-V1V2 immunoglobulin G responses and only rare envelope-specific immunoglobulin A responses..” J Infect Dis 211, no. 4 (February 15, 2015): 508–17. https://doi.org/10.1093/infdis/jiu444.

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Fouda, Genevieve G., and Sallie R. Permar. “Immune-based interventions to prevent postnatal HIV-1 transmission..” Trends Microbiol 22, no. 8 (August 2014): 425–27. https://doi.org/10.1016/j.tim.2014.04.009.

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Zhu, Z., H. R. Qin, W. Chen, Q. Zhao, X. Shen, R. Schutte, Y. Wang, et al. “Erratum to Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies [Journal of Virology, 85, 21, (2011) 11401-11408] DOI: 10.1128/JVI.05312-11.” Journal of Virology, December 1, 2013. https://doi.org/10.1128/JVI.02726-13.

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Fouda, Genevieve G., Frederick H. Jaeger, Joshua D. Amos, Carrie Ho, Erika L. Kunz, Kara Anasti, Lisa W. Stamper, et al. “Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk..” Proc Natl Acad Sci U S A 110, no. 45 (November 5, 2013): 18220–25. https://doi.org/10.1073/pnas.1307336110.

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Amos, Joshua D., Andrew B. Wilks, Genevieve G. Fouda, Shannon D. Smith, Lisa Colvin, Tatenda Mahlokozera, Carrie Ho, et al. “Lack of B cell dysfunction is associated with functional, gp120-dominant antibody responses in breast milk of simian immunodeficiency virus-infected African green monkeys..” J Virol 87, no. 20 (October 2013): 11121–34. https://doi.org/10.1128/JVI.01887-13.

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Fouda, Genevieve G. A., Joshua D. Amos, Andrew B. Wilks, Justin Pollara, Caroline A. Ray, Anjali Chand, Erika L. Kunz, et al. “Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk..” J Virol 87, no. 12 (June 2013): 6986–99. https://doi.org/10.1128/JVI.00528-13.

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Russell, Elizabeth S., Suany Ojeda, Genevieve G. Fouda, Steven R. Meshnick, David Montefiori, Sallie R. Permar, and Ronald Swanstrom. “Short communication: HIV type 1 subtype C variants transmitted through the bottleneck of breastfeeding are sensitive to new generation broadly neutralizing antibodies directed against quaternary and CD4-binding site epitopes..” Aids Res Hum Retroviruses 29, no. 3 (March 2013): 511–15. https://doi.org/10.1089/AID.2012.0197.

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Fouda, Genevieve G., Tatenda Mahlokozera, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Gerald Learn, Surender B. Kumar, S Moses Dennison, et al. “Postnatally-transmitted HIV-1 Envelope variants have similar neutralization-sensitivity and function to that of nontransmitted breast milk variants..” Retrovirology 10 (January 10, 2013). https://doi.org/10.1186/1742-4690-10-3.

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Friedman, James, S Munir Alam, Xiaoying Shen, Shi-Mao Xia, Shelley Stewart, Kara Anasti, Justin Pollara, et al. “Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum..” Plos One 7, no. 5 (2012). https://doi.org/10.1371/journal.pone.0037648.

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