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Ann Marie Reed, MD

Samuel L. Katz Professor of Pediatrics
Professor of Pediatrics
Chair of the Department of Pediatrics
Email address: ann.reed@duke.edu

I have spent my career caring for children with autoimmune disorders and immune dysfunction.  I have focused my work caring for children with juvenile dermatomyositis and auto inflammatory disorders.  I have overseen a research program for 24 years studying the  genetics and cause of human autoimmune disease, focused on dermatomyositis in children and adults. The long-term goal of my research team is to develop new biomarkers of diseases to identify those predisposed to develop disease, as well as monitor disease activity and response to treatment. My team makes extensive use of genomics, gene expression, protein expression and immunohistochemical techniques to study the inflammatory and non-inflammatory aspects of dermatomyositis diseases. Other autoimmune disease processes, including systemic lupus and vasculitis, have been focused on as well.

Education and Training

  • Fellowship, Molecular Genetics, University of Chicago, 1988 - 1990
  • Immunology/Rheumatology Fellowship, Department Of Pediatrics, Northwestern University Feinberg School of Medicine, 1987 - 1990
  • Residency, Department Of Pediatrics, Akron Children's Hospital, 1984 - 1987
  • M.D., Medical College of Ohio, 1984

Publications

Stevens, BE, Torok, KS, Li, SC, Hershey, N, Curran, M, Higgins, GC, Moore, KF, Egla Rabinovich, C, Dodson, S, Stevens, AM, and and the Childhood Arthritis and Rheumatology Research Alliance Registry Investigators, . "Clinical Characteristics and Factors Associated With Disability and Impaired Quality of Life in Children With Juvenile Systemic Sclerosis: Results From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry." Arthritis Care & Research 70, no. 12 (December 2018): 1806-1813.

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Houtman, M, Ekholm, L, Hesselberg, E, Chemin, K, Malmström, V, Reed, AM, Lundberg, IE, and Padyukov, L. "T-cell transcriptomics from peripheral blood highlights differences between polymyositis and dermatomyositis patients." Arthritis Research & Therapy 20, no. 1 (August 29, 2018): 188-null.

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Hinks, A, Marion, MC, Cobb, J, Comeau, ME, Sudman, M, Ainsworth, HC, Bowes, J, Juvenile Idiopathic Arthritis Consortium for Immunochip, , Becker, ML, Bohnsack, JF, Haas, J-P, Lovell, DJ, Mellins, ED, Nelson, JL, Nordal, E, Punaro, M, Reed, AM, Rose, CD, Rosenberg, AM, Rygg, M, Smith, SL, Stevens, AM, Videm, V, Wallace, CA, Wedderburn, LR, Yarwood, A, Yeung, RSM, Langefeld, CD, Thompson, SD, Thomson, W, and Prahalad, S. "Brief Report: The Genetic Profile of Rheumatoid Factor-Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis." Arthritis & Rheumatology (Hoboken, N.J.) 70, no. 6 (June 2018): 957-962.

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Rider, LG, Aggarwal, R, Machado, PM, Hogrel, J-Y, Reed, AM, Christopher-Stine, L, and Ruperto, N. "Update on outcome assessment in myositis." Nature Reviews. Rheumatology 14, no. 5 (May 2018): 303-318. (Review)

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Challa, D, Crowson, CS, Niewold, TB, Reed, AM, and CARRA Legacy Registry Investigators, . "Predictors of changes in disease activity among children with juvenile dermatomyositis enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry." Clinical Rheumatology 37, no. 4 (April 2018): 1011-1015.

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Samad, A, Stoll, ML, Lavi, I, Hsu, JJ, Strand, V, Robinson, TN, Mellins, ED, and Zisman, D. "Adiposity in Juvenile Psoriatic Arthritis." The Journal of Rheumatology 45, no. 3 (March 2018): 411-418.

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Rubinstein, TB, Mowrey, WB, Ilowite, NT, Wahezi, DM, and Childhood Arthritis and Rheumatology Research Alliance INVESTIGATORS, . "Delays to Care in Pediatric Lupus Patients: Data From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry." Arthritis Care & Research 70, no. 3 (March 2018): 420-427.

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McCann, LJ, Pilkington, CA, Huber, AM, Ravelli, A, Appelbe, D, Kirkham, JJ, Williamson, PR, Aggarwal, A, Christopher-Stine, L, Constantin, T, Feldman, BM, Lundberg, I, Maillard, S, Mathiesen, P, Murphy, R, Pachman, LM, Reed, AM, Rider, LG, van Royen-Kerkof, A, Russo, R, Spinty, S, Wedderburn, LR, and Beresford, MW. "Development of a consensus core dataset in juvenile dermatomyositis for clinical use to inform research." Annals of the Rheumatic Diseases 77, no. 2 (February 2018): 241-250.

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Lundberg, IE, Tjärnlund, A, Bottai, M, Werth, VP, Pilkington, C, Visser, MD, Alfredsson, L, Amato, AA, Barohn, RJ, Liang, MH, Singh, JA, Aggarwal, R, Arnardottir, S, Chinoy, H, Cooper, RG, Dankó, K, Dimachkie, MM, Feldman, BM, Torre, IG-DL, Gordon, P, Hayashi, T, Katz, JD, Kohsaka, H, Lachenbruch, PA, Lang, BA, Li, Y, Oddis, CV, Olesinska, M, Reed, AM, Rutkowska-Sak, L, Sanner, H, Selva-O'Callaghan, A, Song, Y-W, Vencovsky, J, Ytterberg, SR, Miller, FW, Rider, LG, International Myositis Classification Criteria Project consortium, and The Euromyositis register and The Juvenile Dermatomyositis Cohort Biomarker Study and Repository (JDRG) (UK and Ireland), . "2017 European League Against Rheumatism/American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups." Annals of the Rheumatic Diseases 76, no. 12 (December 2017): 1955-1964.

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Lundberg, IE, Tjärnlund, A, Bottai, M, Werth, VP, Pilkington, C, de Visser, M, Alfredsson, L, Amato, AA, Barohn, RJ, Liang, MH, Singh, JA, Aggarwal, R, Arnardottir, S, Chinoy, H, Cooper, RG, Dankó, K, Dimachkie, MM, Feldman, BM, Garcia-De La Torre, I, Gordon, P, Hayashi, T, Katz, JD, Kohsaka, H, Lachenbruch, PA, Lang, BA, Li, Y, Oddis, CV, Olesinska, M, Reed, AM, Rutkowska-Sak, L, Sanner, H, Selva-O'Callaghan, A, Song, Y-W, Vencovsky, J, Ytterberg, SR, Miller, FW, Rider, LG, International Myositis Classification Criteria Project Consortium, the Euromyositis Register, and and the Juvenile Dermatomyositis Cohort Biomarker Study and Repository (UK and Ireland), . "2017 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Adult and Juvenile Idiopathic Inflammatory Myopathies and Their Major Subgroups." Arthritis & Rheumatology (Hoboken, N.J.) 69, no. 12 (December 2017): 2271-2282.

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