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Bernard Martin Fischer, DVM, PhD

Associate Professor of Pediatrics
Campus mail: 139 MSRB1, 203 Research Drive, Durham, NC 27710
Phone: (919) 660-0258
Email address: bernie.fischer@duke.edu

Comparative Pharmacology and Cell Biology
Mechanisms of complementary-alternative medicines and products
Signal Transduction and Cell Signaling
Development of both animal and in vitro models of disease
Implications of early life lung injury on long-term immune function and overall health
Mechanisms of inflammation and disease
Cytokine, Oxidant, and Inflammatory Mediator Networking
Integrative care/treatments for HIV patients
Mechanisms of chronic inflammation associated with HIV

Education and Training

  • Ph.D., North Carolina State University, 1997
  • D.V.M., North Carolina State University, 1988

Publications

Meyer, ML, Potts-Kant, EN, Ghio, AJ, Fischer, BM, Foster, WM, and Voynow, JA. "NAD(P)H quinone oxidoreductase1 regulates neutrophil elastase-induced mucous cell metaplasia. Am JPhysiol Lung Cell Mol Physiol 303: L181–L188, 2012; doi:10.1152/ajplung.00084.2012." American journal of physiology. Lung cellular and molecular physiology 309, no. 1 (July 2015): L98-.

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Ledford, JG, Voelker, DR, Addison, KJ, Wang, Y, Nikam, VS, Degan, S, Kandasamy, P, Tanyaratsrisakul, S, Fischer, BM, Kraft, M, and Hollingsworth, JW. "Genetic variation in SP-A2 leads to differential binding to Mycoplasma pneumoniae membranes and regulation of host responses." Journal of immunology (Baltimore, Md. : 1950) 194, no. 12 (June 2015): 6123-6132.

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Fischer, BM, Voynow, JA, and Ghio, AJ. "COPD: balancing oxidants and antioxidants." International journal of chronic obstructive pulmonary disease 10 (January 2015): 261-276. (Review)

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Kelly, FL, Sun, J, Fischer, BM, Voynow, JA, Kummarapurugu, AB, Zhang, HL, Nugent, JL, Beasley, RF, Martinu, T, Gwinn, WM, Morgan, DL, and Palmer, SM. "Diacetyl induces amphiregulin shedding in pulmonary epithelial cells and in experimental bronchiolitis obliterans." American journal of respiratory cell and molecular biology 51, no. 4 (October 2014): 568-574.

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Griffin, KL, Fischer, BM, Kummarapurugu, AB, Zheng, S, Kennedy, TP, Rao, NV, Foster, WM, and Voynow, JA. "2-O, 3-O-desulfated heparin inhibits neutrophil elastase-induced HMGB-1 secretion and airway inflammation." Am J Respir Cell Mol Biol 50, no. 4 (April 2014): 684-689.

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Ledford, JG, Voelker, D, Addison, K, Fischer, BM, Kraft, M, and Hollingsworth, JW. "Genetic Variation In Sp-A1 And Sp-A2 Leads To Differential Binding Of Mycoplasma Membranes And Regulation Of Host Response." 2014.

Scholars@Duke

Fischer, BM, Wong, JK, Degan, S, Kummarapurugu, AB, Zheng, S, Haridass, P, and Voynow, JA. "Increased expression of senescence markers in cystic fibrosis airways." Am J Physiol Lung Cell Mol Physiol 304, no. 6 (March 15, 2013): L394-L400.

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Kummarapurugu, AB, Fischer, BM, Zheng, S, Milne, GL, Ghio, AJ, Potts-Kant, EN, Foster, WM, Soderblom, EJ, Dubois, LG, Moseley, MA, Thompson, JW, and Voynow, JA. "NADPH:quinone oxidoreductase 1 regulates host susceptibility to ozone via isoprostane generation." J Biol Chem 288, no. 7 (February 15, 2013): 4681-4691.

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Ghio, AJ, Soukup, JM, Richards, JH, Fischer, BM, Voynow, JA, and Schmechel, DE. "Deficiency of α-1-antitrypsin influences systemic iron homeostasis." Int J Chron Obstruct Pulmon Dis 8 (2013): 45-51.

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Fischer, BM, Potts-Kant, EN, Kummarapurugu, AB, Zheng, S, Griffin, KL, Kennedy, T, Foster, WM, and Voynow, JA. "Desulfated Heparin: Airway Therapeutic Inhibits Inflammation In Mouse Model Of Obstructive Airway Disease." 2013.

Scholars@Duke

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