Skip to main content

New and competing renewal awards for October 2018 to January 2019

Tuesday, February 5, 2019
McGovern Davison Children's Health Center

The following are new and competing renewal awards made to faculty in the Department of Pediatrics for the months of October through December 2018. Congratulations to these faculty on their awards and best wishes to them in their investigative work.

October 2018

Klaus-Georg Werner (Neurology) received an award from the University of Alabama (National Institutes of Health) in the amount of $24,406 for a project entitled “Preventing Epilepsy Using Vigabatrin in Infants with Tuberous Sclerosis Complex (PREVeNT Trial)”. The project period is 06/01/2018-05/31/2019.

David Van Mater (Hematology-Oncology) received an award from Children’s Hospital of Philadelphia (Children's Tumor Foundation) in the amount of $15,134 for a project entitled “NF1-OPG”. The project period is 02/01/2018 – 01/31/2021.

Charles Gersbach (Biomedical Engineering) and David Van Mater (Hematology-Oncology) received an award from the Gilbert Family Foundation in the amount of $1,775,396 for a project entitled “Genome Editing with Engineered Vectors to Correct Neurofibromatosis Type 1”. The project period is 12/01/2018 – 11/30/2021.

Suhag Parikh (Blood and Marrow Transplantation) received an award from Children’s Hospital Los Angeles in the amount of $5,999 for a project entitled ”Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Following Hematopoietic Stem Cell Transplantation (ACES)”. The project period is 04/01/2018 – 03/31/2022.

November 2018

Dwight D. Koeberl (Medical Genetics) received an award from Baebies Inc. in the amount of $20,710 for a study entitled “Rapid Neonatal Testing for Ammonia Disorder Biomarkers.” National Institutes of Health is a prime sponsor. The project period is 7/1/2018 – 12/31/2018.

Dwight D. Koeberl (Medical Genetics) received an award from Moderna Therapeutics Inc. in the amount of $80,032 for a study entitled “Mapping the Patient Journey in Methylmalonic and Propionic Acidemia: A Longitudinal, Exploratory, Natural History Study to Further Characterize and Describe the Signs and Symptoms of Patients with Organic Acidemias.”  The project period is 11/7/2018 – 8/31/2021.

Michelle J. White (Hospital Medicine) received an award in the amount of $9,270 from Academic Pediatric Association for a project entitled “Changes in the Recreational Built Environment and Youth BMI in Durham, NC.” The project period is 10/1/2018 – 9/30/2019.

Muhammad S. Zafar (Neurology) received an award in the amount of $230,758 from Marinus Pharmaceuticals, Inc. for a study entitled “A Double-blind, Randomized, Placebo-controlled Trial of Adjunctive Ganaxolone Treatment in Children and Young Adults with Cyclin-dependent Kinase-like 5 (CDKL5) Deficiency Disorder (CDD) Followed by Long-term Open-label Treatment.” The project period is 10/30/2018 – 12/31/2022.

Muhammad S. Zafar (Neurology) received an award in the amount of $267,040 from UCB Pharma Inc. for a study entitled “A Multicenter, Open-label Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Intravenous Brivaracetam in Subjects 1 Month to 16 Years of Age with Epilepsy, Phase 2.” The project period is 7/3/2018 – 11/30/2019.

Vinod K. Prasad (Blood and Marrow Transplantation) received an award in the amount of $117,120 from Magenta Therapeutics for a study entitled “A Phase 2, Single-arm, Open-label, Study to Evaluate the Safety and Efficacy of MGTA-456 in Patients with Inherited Metabolic Disorders (IMD) Undergoing Hematopoietic Stem Cell (HSC) Transplantation (HSCT).” The project period is 10/30/2018 – 9/30/2020.

Jennifer A. Rothman (Hematology-Oncology) received an award in the amount of $221,516 from Novartis Pharmaceuticals Corp. for a study entitled “A Phase 2, Multicenter, Open-Label Study to Assess Appropriate Dosing and to Evaluate Safety of Crizanlizumab, with or without Hydroxyurea/Hydroxycarbamide, in Sequential, Descending Age Groups of Pediatric Sickle Cell Disease Patients with Vaso-Occl.” The project period is 5/11/2018 – 6/1/2025.

Mai ElMallah (Pulmonary and Sleep Medicine) received an award in the amount of $13,669 from Vertex Pharmaceuticals Inc. for a study entitled “A Post-approval Observational Study to Evaluate the Long-term Effectiveness and Safety of Orkambi in US Patients who Completed Study VX12-809-105 Part A.” The project period is 6/21/2018 – 4/30/2021.

Matthew Kelly (Infectious Diseases) received an award in the amount of $138,158 from Merck Sharp & Dohme for a study entitled “A Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of a Single Infusion of Bezlotoxumab (MK-6072, Human Monoclonal Antibody to C. difficile Toxin B) in Children.” The project period is 07/01/2018 - 07/31/2022.

Laura E. Schanberg (Rheumatology) received an award in the amount of $46,973 from Boston’s Children Hospital for a study entitled “Expanding HL7 FHIR to Support Post-marketing Research and Surveillance within Multi-source, Chronic Disease Registries.” Food and Drug Administration is a prime sponsor. The project period is 9/1/2018 – 8/31/2019.

Laura E. Schanberg (Rheumatology) received an award in the amount of $6,988,387 from Patient Centered Outcomes Research Institute for a study entitled “Improving Outcomes in Limited Juvenile Idiopathic Arthritis.” The project period is 9/1/2018 – 7/31/2023.

Rachel G. Greenberg (Neonatology) received an award in the amount of $494,216.40 from Canada Royal Milk ULC for a research study entitled “Infant Formula Study.”  The project period is 08/31/2018 – 11/30/2018.

December 2018

Priya S. Kishnani (Medical Genetics) received an award from Amicus Therapeutics Corporation in the amount of $551,971 for a research study entitled “Developing a management approach for patients with the “late-onset” Pompe disease GAA variant identified by newborn screening.”  The project period is 11/29/2018 to11/28/2020.  

Edward C. Smith (Neurology) received an award from Actus Therapeutics in the amount of $155,633 for a research study entitled “Gene Therapy for Pompe Disease.”  The project period is 11/20/2018 – 11/19/2019.

Edward C. Smith (Neurology) received an award from AveXis, Inc. in the amount of $586,741 for a research study entitled “A Prospective, Long Term Registry of Patients with a Diagnosis of Spinal Muscular Atrophy.”  The project period is 12/13/2018 – 10/31/2038.

Michael A. Moody (Infectious Diseases) received an award from Boston Children’s Hospital in the amount of $560,000 for a research study entitled “Defining and Redirecting Influenza Immunity after Imprinting.” National Institutes of Health is a prime sponsor.  The project period is 08/01/2017 – 07/31/2019.

Baodong Sun (Medical Genetics) received an award from Asklepios BioPharmaceutical, Inc. in the amount of $600,000 for a research study entitled “Feasibility of using Bortezomib-based immunosuppressive approach to deplete anti-AAV antibodies in mice.”  The project period is 12/01/2018 – 11/30/2020.

Chi Hornik (Neonatology) received an award from Basilea Pharmaceutica in the amount of $57,796 for a research study entitled “An open-label study to evaluate the single-dose pharmacokinetics and safety of ceftobiprole in neonate and infant subjects aged up to 3 months undergoing treatment with systemic antibiotics.” The research period is 11/28/2018 – 12/31/2021.

January 2019

Debra L. Best (Primary Care) received an award from Duke Endowment in the amount of $269,404 for a research study entitled “Tiered Screening Approach to Direct Early Life Intervention.” The project period is 01/01/2019 – 12/31/2020.

Annabelle N. Chua (Nephrology) received an award from Sanofi U.S. in the amount of $64,993 for a research study entitled “An Open-Label, Randomized, Parallel Group Study to Assess the Safety and Efficacy of Hectorol (Doxercalciferol Capsules) in Pediatric Patients with Chronic Kidney Disease Stages 3 and 4 with Secondary Hyperparathyroidism not yet on Dialysis.” The project period is 11/19/2018 – 08/01/2020.

Kevin D. Hill (Cardiology) and Reid C. Chamberlain (Cardiology) received an award from the Thrasher Research Fund in the amount of $26,750 for a research study entitled “Evaluating Post-Op AKI Criteria in Infants with CHD and the Protective Effects of Acetaminophen.” The project period is 01/01/2019 – 12/31/2020.

Christoph P. Hornik (Critical Care Medicine) received an award from The University of North Carolina at Chapel Hill in the amount of $1,434,590 for a research study entitled “Safety of Sildenafil in Premature Infants at Risk of Bronchopulmonary Dysplasia.” U.S. Food & Drug Administration is a prime sponsor. The project period is 09/02/2018 – 06/30/2019.

Dwight D. Koeberl (Medical Genetics) received an award from Ultragenyx Pharmaceutical in the amount of $20,548 for a research study entitled “A Retrospective Chart Review Study to Assess the Clinical Outcome of Triheptanoin Treatment in Patients with Long-Chain Fatty Acid Oxidation Disorders (LC-FAOD) Treated under Expanded Access Program.” The project period is 01/22/2019 – 04/01/2019.

Andrew P. Landstorm (Cardiology) transferred a NCI Mentored Clinical Scientist Research Career Development Award (K08) from Texas Children’s Hospital to Duke University in the amount of $576,981 for a project entitled “The Role of Junctophilin Type-2 in Cardiac Node Automatic.” The project period is 08/01/2018 – 05/31/2022.

Corinne M. Linardic (Hematology-Oncology) received an award from Alex’s Lemonade Stand Foundation in the amount of $15,012 for a research study entitled “2018 ALSF Million Mile Grant.” The project period is 12/14/2018 – 12/16/2019. 

Ann M. Reed (Rheumatology) received an award from The Cure JM Foundation in the amount of $55,741 for a research study entitled “Precision Decision in the Treatment of Juvenile Dermatomyositis.” The project period is 11/01/2018 – 11/01/2019.

Edward C. Smith (Neurology) received an award from Parent Project Muscular Dystrophy in the amount of $10,000 for a research study entitled “Certified Duchenne Care Center.” The project period is 01/01/2019 – 12/31/2019.

Neeraj K. Surana (Infectious Diseases) received a grant from the NIH’s National Institute of Allergy and Infectious Diseases in the amount of $50,000 for a project entitled “A Comparative Genomic Analysis of Clostridium Immunis.” The project period is 01/08/2019 – 12/31/2020.

Charlene A. Wong (Primary Care) and Charles D. Scales (Surgery) received an award from Duke Endowment in the amount of $175,000 for a research study entitled “An Opioid Prescribing Nudge: Leveraging Behavioral Economics to Reduce Opioid Harm within Health System.” The project period is 02/01/2019 – 08/31/2020.