C. Michael Cotten, MD, professor of pediatrics (Neonatology), was recently named the new chief of the Division of Neonatology in the Department of Pediatrics, effective September 1, 2017.
Dr. Cotten has dedicated his career to neonatal clinical research. He became PI for the Duke site within the Eunice Kennedy Shriver NICHD Neonatal Research Network (NRN) in 2014 after serving as alternate site PI since 2001. He has been extensively involved with the NRN and its clinical trials for 15 years. His most significant contribution to the Network has been the development of an anonymized DNA bank and database, allowing investigators to identify genetic contributions to risk of developing complex diseases unique to extremely low birth weight infants.
Dr. Cotten received his MHS in clinical research from Duke in 2006 and has served as director of clinical research for the Division of Neonatology and the Jean and George Brumley, Jr. Neonatal-Perinatal Research Institute since 2001. He has been a member of the Duke Institutional Review Board (IRB) since 2002 and became an IRB chairperson in July 2014.
Dr. Cotten has led the development of the NRN’s emerging efforts in genomics, and is now chair of the genomics subcommittee. He also serves on the Network’s protocol review subcommittee, as well as the Inositol study subcommittee, which has designed and carried out Phase I and II trials of inositol in extremely preterm infants, and is currently enrolling patients in the phase III pivotal trial.
His work with the NRN has also included serving as site PI for the three clinical trials of therapeutic hypothermia for neonatal brain injury. These studies led to the establishment of collaborations with the maternal-fetal medicine research group and the stem cell research program to initiate a Phase I study of autologous cord blood cells for infants with hypoxic-ischemic encephalopathy.
"Dr. Cotten is an exceptionally talented clinician-scientist who is clearly advancing the field of neonatology and is a recognized leader nationally and internationally, and we are fortunate that he will be serving in this new role in the department,” says Ann M. Reed, MD, chair of the Department of Pediatrics.