Skip to main content

Patricia Lynn Ashley, PhD, MD

Associate Professor of Pediatrics
Campus mail: 2424 Erwin Road, Suite 504, Durham, NC 27705
Phone: (919) 681-3501
Email address: ashle022@mc.duke.edu

My current clinical time is divided between inpatient and outpatient care of infants who graduate from the ICN or TCN.  In addition, I am a provider in our Transitions program for the most medically fragile and complex infants that we care for.
My research interests center on how Nutrition influences growth and development, primarily in infants born extremely premature.  Through a combination of clinical research and basic science involving study of the microbiome and metabolome, we are seeking new answers regarding how to optimize growth, development, and eventual long term outcomes for these infants.
I also have taken on administrative and regulatory roles involving research over the last three years when I became a member of the IRB.  More recently I have taken on the role of Director for the Children's Clinical Research Unit.

Education and Training

  • Resident, Pediatrics, University of Texas at Dallas, 1991 - 1994
  • M.D., University of Texas at Dallas, 1991
  • Ph.D., University of Texas at Dallas, 1984

Publications

Duncan, AF, Bann, CM, Dempsey, A, Peralta-Carcelen, M, Hintz, S, and Eunice Kennedy Shriver National Institute of Child Health and Development Neonatal Research Network, . "Behavioral Deficits at 18-22 Months of Age Are Associated with Early Cerebellar Injury and Cognitive and Language Performance in Children Born Extremely Preterm." The Journal of Pediatrics 204 (January 2019): 148-156.e4.

Full Text

Khan, TN, Khan, K, Sadeghpour, A, Reynolds, H, Perilla, Y, McDonald, MT, Gallentine, WB, Baig, SM, Task Force for Neonatal Genomics, , Davis, EE, and Katsanis, N. "Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies." American Journal of Human Genetics 104, no. 1 (January 2019): 94-111.

Full Text

Vohr, BR, Heyne, R, Bann, CM, Das, A, Higgins, RD, Hintz, SR, Eunice Kennedy Shriver National Institute of Child Health, and and Development Neonatal Research Network, . "Extreme Preterm Infant Rates of Overweight and Obesity at School Age in the SUPPORT Neuroimaging and Neurodevelopmental Outcomes Cohort." The Journal of Pediatrics 200 (September 2018): 132-139.e3.

Full Text

Hintz, SR, Vohr, BR, Bann, CM, Taylor, HG, Das, A, Gustafson, KE, Yolton, K, Watson, VE, Lowe, J, DeAnda, ME, Ball, MB, Finer, NN, Van Meurs, KP, Shankaran, S, Pappas, A, Barnes, PD, Bulas, D, Newman, JE, Wilson-Costello, DE, Heyne, RJ, Harmon, HM, Peralta-Carcelen, M, Adams-Chapman, I, Duncan, AF, Fuller, J, Vaucher, YE, Colaizy, TT, Winter, S, McGowan, EC, Goldstein, RF, Higgins, RD, and SUPPORT study group of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, . "Preterm Neuroimaging and School-Age Cognitive Outcomes." Pediatrics 142, no. 1 (July 2018).

Full Text

Adams-Chapman, I, Heyne, RJ, DeMauro, SB, Duncan, AF, Hintz, SR, Pappas, A, Vohr, BR, McDonald, SA, Das, A, Newman, JE, Higgins, RD, and Follow-Up Study of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, . "Neurodevelopmental Impairment Among Extremely Preterm Infants in the Neonatal Research Network." Pediatrics 141, no. 5 (May 2018).

Full Text

Sarkar, S, Shankaran, S, Barks, J, Do, BT, Laptook, AR, Das, A, Ambalavanan, N, Van Meurs, KP, Bell, EF, Sanchez, PJ, Hintz, SR, Wyckoff, MH, Stoll, BJ, Carlo, WA, and Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, . "Outcome of Preterm Infants with Transient Cystic Periventricular Leukomalacia on Serial Cranial Imaging Up to Term Equivalent Age." The Journal of Pediatrics 195 (April 2018): 59-65.e3.

Full Text

Pappas, A, Adams-Chapman, I, Shankaran, S, McDonald, SA, Stoll, BJ, Laptook, AR, Carlo, WA, Van Meurs, KP, Hintz, SR, Carlson, MD, Brumbaugh, JE, Walsh, MC, Wyckoff, MH, Das, A, Higgins, RD, and Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, . "Neurodevelopmental and Behavioral Outcomes in Extremely Premature Neonates With Ventriculomegaly in the Absence of Periventricular-Intraventricular Hemorrhage." Jama Pediatrics 172, no. 1 (January 2018): 32-42.

Full Text

James, J, Munson, D, DeMauro, SB, Langer, JC, Dworetz, AR, Natarajan, G, Bidegain, M, Fortney, CA, Seabrook, R, Vohr, BR, Tyson, JE, Bell, EF, Poindexter, BB, Shankaran, S, Higgins, RD, Das, A, Stoll, BJ, Kirpalani, H, and Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, . "Outcomes of Preterm Infants following Discussions about Withdrawal or Withholding of Life Support." The Journal of Pediatrics 190 (November 2017): 118-123.e4.

Full Text

Younge, N, Goldstein, RF, Bann, CM, Hintz, SR, Patel, RM, Smith, PB, Bell, EF, Rysavy, MA, Duncan, AF, Vohr, BR, Das, A, Goldberg, RN, Higgins, RD, Cotten, CM, and Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, . "Survival and Neurodevelopmental Outcomes among Periviable Infants." The New England Journal of Medicine 376, no. 7 (February 2017): 617-628.

Full Text

Navarrete, CT, Wrage, LA, Carlo, WA, Walsh, MC, Rich, W, Gantz, MG, Das, A, Schibler, K, Newman, NS, Piazza, AJ, Poindexter, BB, Shankaran, S, Sánchez, PJ, Morris, BH, Frantz, ID, Van Meurs, KP, Cotten, CM, Ehrenkranz, RA, Bell, EF, Watterberg, KL, Higgins, RD, Duara, S, and Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, . "Growth Outcomes of Preterm Infants Exposed to Different Oxygen Saturation Target Ranges from Birth." The Journal of Pediatrics 176 (September 2016): 62-68.e4.

Full Text

Pages