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Michael Anthony Moody, MD

Associate Professor of Pediatrics
Associate Professor in the Department of Immunology
Member of the Duke Human Vaccine Institute
Campus mail: 2 Genome Ct, MSRB II Room 3007, Durham, NC 27710
Phone: (919) 668-2551
Email address: tony.moody@duke.edu

Tony Moody, MD is an Associate Professor in the Department of Pediatrics, Division of Infectious Diseases and the Department of Immunology at Duke University Medical Center. Research in the Moody lab is focused on understanding the B cell responses during infection, vaccination, and disease. The lab has become a resource for human phenotyping, flow characterization, staining and analysis at the Duke Human Vaccine Institute (DHVI). The Moody lab is currently funded to study influenza, syphilis, HIV-1, and emerging infectious diseases.

Dr. Moody is the director of the Duke CIVICs Vaccine Center (DCVC) at (DHVI) and co-director of the Centers for Research of Emerging Infectious Disease Coordinating Center (CREID-CC). Dr. Moody is co-PI of a U19 program to develop a syphilis vaccine; this program is led by Dr. Justin Radolf at the University of Connecticut. Dr. Moody is also the director of the DHVI Accessioning Unit, a biorepository that provides support for work occurring at DHVI and with its many collaborators around the world by providing processing, shipping, and inventory support for a wide array of projects.

Dr. Moody and his team are involved in many networks studying vaccine response including the Collaborative Influenza Vaccine Innovation Centers (CIVICs), HIV Vaccine Trials Network (HVTN) and the COVID-19 Prevention Network (CoVPN).

Education and Training

  • Fellowship, Pediatric Infectious Diseases, Pediatrics, Duke University, 2003 - 2006
  • Pediatric Chief Resident, Pediatrics, Emory University, 2002 - 2003
  • Pediatric Internship & Residency, Pediatrics, Emory University, 1999 - 2002
  • M.D., Duke University, 1999

Selected Grants and Awards

Publications

Raymond, Donald D., Shaun M. Stewart, Jiwon Lee, Jack Ferdman, Goran Bajic, Khoi T. Do, Michael J. Ernandes, et al. “Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.” Nat Med 22, no. 12 (December 2016): 1465–69. https://doi.org/10.1038/nm.4223.

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Bradley, Todd, Ashley Trama, Nancy Tumba, Elin Gray, Xiaozhi Lu, Navid Madani, Fatemeh Jahanbakhsh, et al. “Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity.” Ebiomedicine 12 (October 2016): 196–207. https://doi.org/10.1016/j.ebiom.2016.08.045.

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Buchbinder, Susan, Nicole Grunenberg, Brittany Sanchez, Kelly Seaton, Guido Ferrari, M Anthony Moody, Nicole Frahm, et al. “DNA/MVA HIV Vaccine Producing Virus-like Particles (VLPs) Is Well-tolerated and Induces Durable Functional Antibodies (Abs) in HVTN 094.” In Aids Research and Human Retroviruses, 32:99–99. MARY ANN LIEBERT, INC, 2016.

Scholars@Duke

Doria-Rose, Nicole A., Shelly Krebs, Wiliam Law, Syna Gift, Agnes Chenine, Morgane Rolland, M Anthony Moody, et al. “HIV-1 MPER-directed Broadly Neutralizing Antibodies from an Acute-infection Cohort RV217 Subject.” In Aids Research and Human Retroviruses, 32:36–36. MARY ANN LIEBERT, INC, 2016.

Scholars@Duke

Madani, Navid, Amy Princiotto, David Easterhoff, Todd Bradley, Kan Luo, M Anthony Moody, Ganesh Phad, et al. “Prevention of Vaginal Transmission of Simian-Human Immunodeficiency Virus (SHIV) in Rhesus Monkeys by Small-molecule CD4-mimetic Compounds.” In Aids Research and Human Retroviruses, 32:129–129. MARY ANN LIEBERT, INC, 2016.

Scholars@Duke

Saleh, Ezzeldin, M Anthony Moody, and Emmanuel B. Walter. “Effect of antipyretic analgesics on immune responses to vaccination.” Hum Vaccin Immunother 12, no. 9 (September 2016): 2391–2402. https://doi.org/10.1080/21645515.2016.1183077.

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Tay, Matthew Zirui, Pinghuang Liu, LaTonya D. Williams, Michael D. McRaven, Sheetal Sawant, Thaddeus C. Gurley, Thomas T. Xu, et al. “Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses.” Plos Pathog 12, no. 8 (August 2016): e1005817. https://doi.org/10.1371/journal.ppat.1005817.

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Moody, M Anthony, Isabela Pedroza-Pacheco, Nathan A. Vandergrift, Cecilia Chui, Krissey E. Lloyd, Robert Parks, Kelly A. Soderberg, et al. “Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies.” Sci Immunol 1, no. 1 (July 29, 2016): aag0851. https://doi.org/10.1126/sciimmunol.aag0851.

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Dudley, Dawn M., Matthew T. Aliota, Emma L. Mohr, Andrea M. Weiler, Gabrielle Lehrer-Brey, Kim L. Weisgrau, Mariel S. Mohns, et al. “A rhesus macaque model of Asian-lineage Zika virus infection.” Nat Commun 7 (June 28, 2016): 12204. https://doi.org/10.1038/ncomms12204.

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Bushey, Ryan T., M Anthony Moody, Nathan L. Nicely, Barton F. Haynes, S Munir Alam, Stephen T. Keir, Rex C. Bentley, et al. “A Therapeutic Antibody for Cancer, Derived from Single Human B Cells.” Cell Rep 15, no. 7 (May 17, 2016): 1505–13. https://doi.org/10.1016/j.celrep.2016.04.038.

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