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Michael Anthony Moody, MD

Associate Professor of Pediatrics
Associate Professor in the Department of Immunology
Member of the Duke Human Vaccine Institute
Campus mail: 2 Genome Ct, MSRB II Room 3007, Durham, NC 27710
Phone: (919) 668-2551
Email address: tony.moody@duke.edu

Tony Moody, MD is an Associate Professor in the Department of Pediatrics, Division of Infectious Diseases and the Department of Immunology at Duke University Medical Center. Research in the Moody lab is focused on understanding the B cell responses during infection, vaccination, and disease. The lab has become a resource for human phenotyping, flow characterization, staining and analysis at the Duke Human Vaccine Institute (DHVI). The Moody lab is currently funded to study influenza, syphilis, HIV-1, and emerging infectious diseases.

Dr. Moody is the director of the Duke CIVICs Vaccine Center (DCVC) at (DHVI) and co-director of the Centers for Research of Emerging Infectious Disease Coordinating Center (CREID-CC). Dr. Moody is co-PI of a U19 program to develop a syphilis vaccine; this program is led by Dr. Justin Radolf at the University of Connecticut. Dr. Moody is also the director of the DHVI Accessioning Unit, a biorepository that provides support for work occurring at DHVI and with its many collaborators around the world by providing processing, shipping, and inventory support for a wide array of projects.

Dr. Moody and his team are involved in many networks studying vaccine response including the Collaborative Influenza Vaccine Innovation Centers (CIVICs), HIV Vaccine Trials Network (HVTN) and the COVID-19 Prevention Network (CoVPN).

Education and Training

  • Fellowship, Pediatric Infectious Diseases, Pediatrics, Duke University, 2003 - 2006
  • Pediatric Chief Resident, Pediatrics, Emory University, 2002 - 2003
  • Pediatric Internship & Residency, Pediatrics, Emory University, 1999 - 2002
  • M.D., Duke University, 1999

Selected Grants and Awards

Publications

Moody, M Anthony, Sampa Santra, Nathan A. Vandergrift, Laura L. Sutherland, Thaddeus C. Gurley, Mark S. Drinker, Ashley A. Allen, et al. “Toll-like receptor 7/8 (TLR7/8) and TLR9 agonists cooperate to enhance HIV-1 envelope antibody responses in rhesus macaques.” J Virol 88, no. 6 (March 2014): 3329–39. https://doi.org/10.1128/JVI.03309-13.

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Seaton, Kelly E., Lamar Ballweber, Audrey Lan, Michele Donathan, Sean Hughes, Lucia Vojtech, M Anthony Moody, et al. “HIV-1 specific IgA detected in vaginal secretions of HIV uninfected women participating in a microbicide trial in Southern Africa are primarily directed toward gp120 and gp140 specificities.” Plos One 9, no. 7 (2014): e101863. https://doi.org/10.1371/journal.pone.0101863.

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Moody, M. A. “Modulation of HIV-1 immunity by adjuvants.” Current Opinion in Hiv and Aids 9, no. 3 (2014): 242–49. https://doi.org/10.1097/COH.0000000000000052.

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Kepler, Thomas B., Supriya Munshaw, Kevin Wiehe, Ruijun Zhang, Jae-Sung Yu, Christopher W. Woods, Thomas N. Denny, et al. “Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation.” Front Immunol 5 (2014): 170. https://doi.org/10.3389/fimmu.2014.00170.

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Zhu, Z., H. R. Qin, W. Chen, Q. Zhao, X. Shen, R. Schutte, Y. Wang, et al. “Erratum to Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies [Journal of Virology, 85, 21, (2011) 11401-11408] DOI: 10.1128/JVI.05312-11.” Journal of Virology, December 1, 2013. https://doi.org/10.1128/JVI.02726-13.

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Williams, W. B., K. Jones, P. Liu, A. M. Trama, K. Seaton, M. A. Moody, N. Vandergrift, et al. “Antibody Repertoire Induced by the Multiclade (Env A, B, C) HIV-1 DNA Prime, rAd5 Boost VRC Vaccine.” In Aids Research and Human Retroviruses, 29:A9–A9. MARY ANN LIEBERT, INC, 2013.

Scholars@Duke

Kunz, E., G. Fouda, C. Ho, J. Amos, L. Colvin, D. Montefiori, A. Martelli, et al. “Combined Mucosal and Systemic C.1086 Envelope Immunization of Lactating Monkeys Induces Potent IgA and Functional IgG Antibody Responses in Milk.” In Aids Research and Human Retroviruses, 29:A180–A180. MARY ANN LIEBERT, INC, 2013.

Scholars@Duke

Sacha, C. R., N. Vandergrift, D. J. Marshall, T. C. Gurley, L. Stiegel, J. F. Whitesides, J. Friedman, et al. “Distinct VH Gene Usage and HIV Envelope Specificity of Colostrum and Peripheral B Cell Monoclonal Antibodies of HIV-Infected, Lactating African Women.” In Aids Research and Human Retroviruses, 29:A169–70. MARY ANN LIEBERT, INC, 2013.

Scholars@Duke

Pollara, J., M. Bonsignori, M. Moody, S. Alam, K. Hwang, T. C. Gurley, D. M. Kozink, et al. “Heterogeneity of Anti-V2 ADCC Ab Responses and Implications for Vaccine Development.” In Aids Research and Human Retroviruses, 29:A41–A41. MARY ANN LIEBERT, INC, 2013.

Scholars@Duke

Trama, A. M., H. Liao, F. H. Jaeger, S. M. Alam, K. Wiehe, T. L. Jeffries, A. Foulger, et al. “Intestinal Commensal Bacteria Shape the Pre-transmission Antibody Repertoire to HIV-1 Infection.” In Aids Research and Human Retroviruses, 29:A105–A105. MARY ANN LIEBERT, INC, 2013.

Scholars@Duke

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