Skip to main content

David Sinclaire Van Mater

Assistant Professor of Pediatrics
Member of the Duke Cancer Institute
Campus mail: 102382, Durham, NC 27710
Phone: (919) 684-8111
Email address: david.vanmater@duke.edu

I am a pediatric oncologist with a specific interest in hereditary cancer syndromes and sarcoma. I also director of the Duke Comprehensive Neurofibromatosis Clinic where I see children and adults with neurofibromatosis type I and II, in addition to schwannomatosis. 

Education and Training

  • Pediatric Hematology/Oncology Fellowship, Pediatrics, Duke University School of Medicine, 2009 - 2013
  • Pediatrics Internship and Residency, Pediatrics, University of Michigan at Ann Arbor, 2006 - 2009
  • MD./PhD., University of Michigan at Ann Arbor, 2006

Publications

Lee, Chang-Lung, Yvonne M. Mowery, Andrea R. Daniel, Dadong Zhang, Alexander B. Sibley, Joe R. Delaney, Amy J. Wisdom, et al. “Mutational landscape in genetically engineered, carcinogen-induced, and radiation-induced mouse sarcoma..” Jci Insight 4, no. 13 (July 11, 2019). https://doi.org/10.1172/jci.insight.128698.

Full Text

Bose, Shree, Joanna Robles, Chad M. McCall, Anand S. Lagoo, Daniel S. Wechsler, Gary R. Schooler, and David Van Mater. “Favorable response to nivolumab in a young adult patient with metastatic histiocytic sarcoma..” Pediatr Blood Cancer 66, no. 1 (January 2019). https://doi.org/10.1002/pbc.27491.

Full Text

Van Mater, David, and Lars Wagner. “Management of recurrent Ewing sarcoma: challenges and approaches..” Onco Targets Ther 12 (2019): 2279–88. https://doi.org/10.2147/OTT.S170585.

Full Text

Van Mater, David, Eric Xu, Anupama Reddy, Leonor Añó, Mohit Sachdeva, Wesley Huang, Nerissa Williams, et al. “Injury promotes sarcoma development in a genetically and temporally restricted manner..” Jci Insight 3, no. 20 (October 18, 2018). https://doi.org/10.1172/jci.insight.123687.

Full Text

Narine, Kalindi Y., Christopher C. Oh, Herbert E. Fuchs, and David Van Mater. “Calvarial mass as a presenting feature of neurofibromatosis type 2 in a pediatric patient..” Am J Med Genet A 176, no. 1 (January 2018): 246–47. https://doi.org/10.1002/ajmg.a.38505.

Full Text

Huang, Jianguo, Mark Chen, Melodi Javid Whitley, Hsuan-Cheng Kuo, Eric S. Xu, Andrea Walens, Yvonne M. Mowery, et al. “Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma..” Nat Commun 8 (July 10, 2017). https://doi.org/10.1038/ncomms15999.

Full Text

Sayour, Elias J., Talal Mousallem, David Van Mater, Endi Wang, Paul Martin, Rebecca H. Buckley, and Raymond C. Barfield. “Bone marrow transplantation for CVID-like humoral immune deficiency associated with red cell aplasia..” Pediatr Blood Cancer 63, no. 10 (October 2016): 1856–59. https://doi.org/10.1002/pbc.26092.

Full Text

Van Mater, David, Leonor Añó, Jordan M. Blum, Micah T. Webster, WeiQiao Huang, Nerissa Williams, Yan Ma, Diana M. Cardona, Chen-Ming Fan, and David G. Kirsch. “Acute tissue injury activates satellite cells and promotes sarcoma formation via the HGF/c-MET signaling pathway..” Cancer Res 75, no. 3 (February 1, 2015): 605–14. https://doi.org/10.1158/0008-5472.CAN-14-2527.

Full Text

Dodd, Rebecca D., Leonor Añó, Jordan M. Blum, Zhizhong Li, David Van Mater, and David G. Kirsch. “Methods to generate genetically engineered mouse models of soft tissue sarcoma..” Methods Mol Biol 1267 (2015): 283–95. https://doi.org/10.1007/978-1-4939-2297-0_13.

Full Text

Sachdeva, Mohit, Jeffrey K. Mito, Chang-Lung Lee, Minsi Zhang, Zhizhong Li, Rebecca D. Dodd, David Cason, et al. “MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes..” J Clin Invest 124, no. 10 (October 2014): 4305–19. https://doi.org/10.1172/JCI77116.

Full Text

Pages