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Coleen Kathryn Cunningham, MD

Professor of Pediatrics
Chief, Division of Global Health, Pediatrics
Vice Chair of Research in the Department of Pediatrics
Research Professor of Global Health
Professor of Pathology
Campus mail: Box 3352 Med Ctr, Durham, NC 27710
Phone: (919) 684-6335
Email address: coleen.cunningham@duke.edu

Dr. Cunningham is a pediatric infectious diseases physician who has focused her research on the prevention and treatment of HIV infection in children.  She has also played important roles in evaluation of vaccines for other infectious diseases and recently has worked on Ebola virus treatment studies.  She is currently working on studies of active and passive immunization to prevent HIV transmission in neonates born to HIV infected women.

Education and Training

  • Fellow, Pediatric Infectious Diseases, Pediatrics, SUNY Upstate Medical University, 1988 - 1991
  • Residency, Pediatrics, SUNY Upstate Medical University, 1985 - 1988
  • M.D., SUNY Upstate Medical University, 1985

Selected Grants and Awards

Publications

Tsalik, Ephraim L., Coleen K. Cunningham, Hannah M. Cunningham, Maria G. Lopez-Marti, Devdutta G. Sangvai, William K. Purdy, Deverick J. Anderson, et al. “An Infection Control Program for a 2009 influenza A H1N1 outbreak in a university-based summer camp..” J Am Coll Health 59, no. 5 (2011): 419–26. https://doi.org/10.1080/07448481.2010.534215.

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Saunders, Kevin O., Cavin Ward-Caviness, Robert J. Schutte, Stephanie A. Freel, R Glenn Overman, Nathan M. Thielman, Coleen K. Cunningham, Thomas B. Kepler, and Georgia D. Tomaras. “Secretion of MIP-1β and MIP-1α by CD8(+) T-lymphocytes correlates with HIV-1 inhibition independent of coreceptor usage..” Cell Immunol 266, no. 2 (2011): 154–64. https://doi.org/10.1016/j.cellimm.2010.09.011.

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Saunders, Kevin O., Stephanie A. Freel, R Glenn Overman, Coleen K. Cunningham, and Georgia D. Tomaras. “Epigenetic regulation of CD8(+) T-lymphocyte mediated suppression of HIV-1 replication..” Virology 405, no. 1 (September 15, 2010): 234–42. https://doi.org/10.1016/j.virol.2010.06.001.

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Buchanan, Ann M., Florida J. Muro, Jean Gratz, John A. Crump, Augustine M. Musyoka, Moses W. Sichangi, Anne B. Morrissey, et al. “Establishment of haematological and immunological reference values for healthy Tanzanian children in Kilimanjaro Region..” Trop Med Int Health 15, no. 9 (September 2010): 1011–21. https://doi.org/10.1111/j.1365-3156.2010.02585.x.

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Brogly, Susan B., Mark J. Abzug, D Heather Watts, Coleen K. Cunningham, Paige L. Williams, James Oleske, Daniel Conway, Rhoda S. Sperling, Hans Spiegel, and Russell B. Van Dyke. “Birth defects among children born to human immunodeficiency virus-infected women: pediatric AIDS clinical trials protocols 219 and 219C..” Pediatr Infect Dis J 29, no. 8 (August 2010): 721–27. https://doi.org/10.1097/INF.0b013e3181e74a2f.

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Emmett, Susan D., Coleen K. Cunningham, Blandina T. Mmbaga, Grace D. Kinabo, Werner Schimana, Mark E. Swai, John A. Bartlett, John A. Crump, and Elizabeth A. Reddy. “Predicting virologic failure among HIV-1-infected children receiving antiretroviral therapy in Tanzania: a cross-sectional study..” J Acquir Immune Defic Syndr 54, no. 4 (August 2010): 368–75. https://doi.org/10.1097/QAI.0b013e3181cf4882.

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Cunningham, Coleen K., Bret J. Rudy, Jiahong Xu, James Bethel, Bill G. Kapogiannis, Sushma Ahmad, Craig M. Wilson, Patricia M. Flynn, and Patricia M. Adolescent Medicine Trials Network for HIV/AIDS Interventions. “Randomized trial to determine safety and immunogenicity of two strategies for hepatitis B vaccination in healthy urban adolescents in the United States..” Pediatr Infect Dis J 29, no. 6 (June 2010): 530–34. https://doi.org/10.1097/INF.0b013e3181d285c7.

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Mehta, Nishaki, Coleen K. Cunningham, Patricia Flynn, Joyce Pepe, Stephen Obaro, Bill G. Kapogiannis, James Bethel, Katherine Luzuriaga, and Katherine Adolescent Trials Network for HIV/AIDS Interventions. “Impaired generation of hepatitis B virus-specific memory B cells in HIV infected individuals following vaccination..” Vaccine 28, no. 21 (May 7, 2010): 3672–78. https://doi.org/10.1016/j.vaccine.2010.03.022.

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Freel, Stephanie A., Laurie Lamoreaux, Pratip K. Chattopadhyay, Kevin Saunders, David Zarkowsky, R Glenn Overman, Christina Ochsenbauer, et al. “Phenotypic and functional profile of HIV-inhibitory CD8 T cells elicited by natural infection and heterologous prime/boost vaccination..” J Virol 84, no. 10 (May 2010): 4998–5006. https://doi.org/10.1128/JVI.00138-10.

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Tsalik, Ephraim L., Edward F. Hendershot, Devdutta G. Sangvai, Hannah M. Cunningham, Coleen K. Cunningham, Maria G. Lopez-Marti, William K. Purdy, Christopher W. Woods, and L Brett Caram. “Clinical presentation and response to treatment of novel influenza A H1N1 in a university-based summer camp population..” J Clin Virol 47, no. 3 (March 2010): 286–88. https://doi.org/10.1016/j.jcv.2009.12.012.

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