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Coleen Kathryn Cunningham, MD

Professor of Pediatrics
Chief, Division of Global Health, Pediatrics
Vice Chair of Research in the Department of Pediatrics
Research Professor of Global Health
Professor of Pathology
Campus mail: Box 3352 Med Ctr, Durham, NC 27710
Phone: (919) 684-6335
Email address: coleen.cunningham@duke.edu

Dr. Cunningham is a pediatric infectious diseases physician who has focused her research on the prevention and treatment of HIV infection in children.  She has also played important roles in evaluation of vaccines for other infectious diseases and recently has worked on Ebola virus treatment studies.  She is currently working on studies of active and passive immunization to prevent HIV transmission in neonates born to HIV infected women.

Education and Training

  • Fellow, Pediatric Infectious Diseases, Pediatrics, State University of New York Upstate Medical University, 1988 - 1991
  • Residency, Pediatrics, State University of New York Upstate Medical University, 1985 - 1988
  • M.D., State University of New York Upstate Medical University, 1985

Selected Grants and Awards

Publications

Cunningham, Coleen K., and Elizabeth McFarland. “Vaccines for prevention of mother-to-child transmission of HIV.” Curr Opin Hiv Aids 3, no. 2 (March 2008): 151–54. https://doi.org/10.1097/COH.0b013e3282f50c0f.

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Kiser, Jennifer J., Courtney V. Fletcher, Patricia M. Flynn, Coleen K. Cunningham, Craig M. Wilson, Bill G. Kapogiannis, Hanna Major-Wilson, et al. “Pharmacokinetics of antiretroviral regimens containing tenofovir disoproxil fumarate and atazanavir-ritonavir in adolescents and young adults with human immunodeficiency virus infection.” Antimicrob Agents Chemother 52, no. 2 (February 2008): 631–37. https://doi.org/10.1128/AAC.00761-07.

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Jaspan, Heather B., Coleen K. Cunningham, Tim J. P. Tucker, Peter F. Wright, Steve G. Self, Rebecca L. Sheets, Audrey S. Rogers, et al. “Inclusion of adolescents in preventive HIV vaccine trials: public health policy and research design at a crossroads.” J Acquir Immune Defic Syndr 47, no. 1 (January 1, 2008): 86–92. https://doi.org/10.1097/QAI.0b013e31815d2f27.

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Ku, Cheng-Lung, Horst von Bernuth, Capucine Picard, Shen-Ying Zhang, Huey-Hsuan Chang, Kun Yang, Maya Chrabieh, et al. “Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity.” J Exp Med 204, no. 10 (October 1, 2007): 2407–22. https://doi.org/10.1084/jem.20070628.

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Wiznia, Andrew, Joseph Church, Patricia Emmanuel, Stephen Eppes, Lucy Rowell, Claire Evans, Anne Bertasso, and Anne T20-310 Study Group. “Safety and efficacy of enfuvirtide for 48 weeks as part of an optimized antiretroviral regimen in pediatric human immunodeficiency virus 1-infected patients.” Pediatr Infect Dis J 26, no. 9 (September 2007): 799–805. https://doi.org/10.1097/INF.0b013e318124a9a9.

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McKinney, Ross E., John Rodman, Chengcheng Hu, Paula Britto, Michael Hughes, Mary Elizabeth Smith, Leslie K. Serchuck, et al. “Long-term safety and efficacy of a once-daily regimen of emtricitabine, didanosine, and efavirenz in HIV-infected, therapy-naive children and adolescents: Pediatric AIDS Clinical Trials Group Protocol P1021.” Pediatrics 120, no. 2 (August 2007): e416–23. https://doi.org/10.1542/peds.2006-0925.

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Newell, Marie-Louise, Sharon Huang, Simona Fiore, Claire Thorne, Laurent Mandelbrot, John L. Sullivan, Robert Maupin, et al. “Characteristics and management of HIV-1-infected pregnant women enrolled in a randomised trial: differences between Europe and the USA.” Bmc Infect Dis 7 (June 20, 2007): 60. https://doi.org/10.1186/1471-2334-7-60.

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Dixon, Terry C., and Coleen K. Cunningham. “Treatment of children with HIV infection.” Curr Hiv/Aids Rep 4, no. 2 (May 2007): 93–99. https://doi.org/10.1007/s11904-007-0014-9.

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Witt, Kristine L., Coleen K. Cunningham, Kristine B. Patterson, Grace E. Kissling, Stephen D. Dertinger, Elizabeth Livingston, and Jack B. Bishop. “Elevated frequencies of micronucleated erythrocytes in infants exposed to zidovudine in utero and postpartum to prevent mother-to-child transmission of HIV.” Environ Mol Mutagen 48, no. 3–4 (April 2007): 322–29. https://doi.org/10.1002/em.20266.

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Witt, K. L., C. K. Cunningham, K. B. Patterson, G. E. Kissling, S. D. Dertinger, E. Livingston, and J. B. Bishop. “Micronucleated erythrocyte frequencies in infants exposed to nucleoside antiretroviral drugs in utero and for 6 weeks postnatally to prevent mother-to-child transmission of HIV.” In Environmental and Molecular Mutagenesis, 47:437–437. WILEY-LISS, 2006.

Scholars@Duke

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