| Research |
Initiatives
Departmental Thematic Research Programs
The purpose of Thematic Research Programs is to encourage
researchers to become more involved in interdisciplinary and
cooperative research initiatives. These programs encourage physicians and scientists
from different domains to cooperate in cutting edge research with their
peers throughout the Duke University research community and beyond. Research in the Department of Pediatrics is principally defined by the following thematic areas:
Biomedical investigators in each of the Divisions within the Department of Pediatrics conduct research, whether
through exploring the molecular basis of disease in laboratories,
testing new treatments in clinical trials, or identifying factors that
promote disease or health in the community. For more information on the
many research activities at Duke Pediatrics, select
a research area below.
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The Alice and Y.T. Chen Pediatric Genetics and Genomics Research Center focuses on single gene disorders amenable to enzyme
replacement therapy or gene therapy. More>>
Jean and George Brumley, Jr. Neonatal Perinatal Research Institute (NPRI)
The Jean and George Brumley, Jr. Neonatal Perinatal Research Institute (NPRI), established in 1997,
is dedicated to developmental biology and focuses its research on the
serious health problems of newborns. Among the areas of active
investigation are the mechanisms of brain, lung and cardiovascular
injury and the cellular etiology of birth defects. More>>
Federally Sponsored Research Networks
The Department of Pediatrics participates in a number of federally funded clinical research networks. These networks and their principal investigators are listed below.
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Network |
Pediatric Principal Investigator |
Global Health Research Initiatives
Faculty in the Department of Pediatrics are involved in a number of global research initiatives facilitated by the Duke Global Health Institute (DGHI). The Duke Global Health Institute is committed
to reducing health disparities in the local community and in resource-limited regions of the
world. Recognizing that many
global health problems arise from economic, social, environmental,
political and health care inequalities, DGHI brings together
interdisciplinary teams to solve complex health problems and to train
the next generation of global health scholars.
Department of Pediatrics faculty who are currently involved in global health efforts in education, research, policy or service are listed here. As the passion for global health grows within the Duke community, we expect this list to expand. Please check back often for updates.
Department of Pediatrics faculty who are currently involved in global health efforts in education, research, policy or service are listed here. As the passion for global health grows within the Duke community, we expect this list to expand. Please check back often for updates.
Duke Translational Medicine Institute (DTMI)
The Duke Translational Medicine Institute (DTMI) Pediatrics Core was established to specifically address the increasing need for a coherent and integrated method for the conduct of pediatric clinical and translational research projects due to FDA pediatric initiatives and the proliferation of NIH-funded mechanisms for pediatric research.The mission of the DTMI Pediatrics Core resource is to provide a leading
pediatric academic enterprise that promotes measurable improvements in the health of children by
fostering the translation of new scientific discoveries into clinical practice through collaborative clinical and
translational research. The Pediatrics Core will provide both the training and the
opportunity for established and newly-trained investigators to use
their skills in pediatric translational studies and clinical
research.
To learn more about the organizational objectives, major initiatives and faculty affiliated with DTMI Pediatrics, please visit the Pediatrics and Pediatric Management section of the DTMI web site.
Duke Clinical Research Institute (DCRI)
The Duke Clinical Research Institute (DCRI), the world's largest academic clinical research organization, conducts pediatric clinical trials on
an unprecedented scale. These trials involve thousands of participants from
across the globe and combine the clinical expertise and academic leadership of a premier teaching hospital with the full-service operational capabilities of a major contract research organization. DCRI pediatric research experience ranges from pharmacokinetic
studies in neonates to large, multi-center trials in adolescent
populations. The faculty are renowned, experienced researchers
in all of the most crucial therapeutic areas, and are also
practicing physicians, observing the results of hard-won evidence
right at the bedside.
Added to this academic and clinical
expertise is the unique operational capability of the DCRI making it the undisputed world leader in pediatric clinical research.
To learn more about DCRI-sponsored pediatric research activities, please visit the Pediatric Research Activities section of the DCRI web site. Department of Pediatrics faculty who are currently affiliated with DCRI are listed here.
Duke Clinical Research Unit (DCRU)
The Duke Clinical Research Unit (DCRU) provides specialized facilities,
staff, resources, and expertise in conducting early phase clinical
research with the goal of facilitating the understanding of human conditions, translating basic research findings into patient care, and developing new therapies.
The following services are available for early phase pediatric clinical research:
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Project management
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Research coordination
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Biostatistics
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Data management
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Randomization
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Lab sample collection and processing
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Subject recruitment
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Subject reimbursement
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Pharmacy services: Packaging; Drug storage; Drug dispensing




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