Division of Rheumatology

Research

Overview

The Division of Pediatric Rheumatology is actively engaged in clinical research to improve the care of children with rheumatic disease. This includes research studies funded by the NIH and foundations, as well as industry. We currently have active clinical trials in systemic juvenile arthritis, polyarticular juvenile idiopathic arthritis, systemic lupus erythematosus, juvenile dermatomyositis, pediatric scleroderma, inflammatory eye disease, and drug safety.

Research Faculty

Name	Areas of Special Interest
Laura E. Schanberg, MD, Co- Chief	Pain in children with arthritis, treatment of juvenile arthritis, atherosclerosis in pediatric systemic lupus erythematosus, clinical trials in rare childhood diseases
Egla C. Rabinovich , MD, Co-Chief	Treatment of childhood rheumatic diseases, treatment of inflammatory eye disease, drug safety, childhood osteoporosis, treatment of juvenile dermatomyositis, classification and treatment of linear scleroderma
Heather Van Mater, MD	Pediatric rheumatology workforce, cost-effective treatments in rheumatic disease, systemic onset juvenile arthritis, localized scleroderma.

Clinical Research

Clinical trial of atorvastatin in preventing atherosclerosis in pediatric lupus erythematosus
Testing efficacy measures for pediatric lupus studies
Clinical trial of early aggressive treatment in polyarticular juvenile idiopathic arthritis
Clinical trial of adalimumab treatment in young children (2 to <4) years old with active juvenile idiopathic arthritis
Clinical trial of tocilumab treatment in children with active systemic juvenile idiopathic arthritis
Clinical trial of rituximab treatment in juvenile dermatomyositis
Electronic daily diary assessment of pain in juvenile arthritis
Multicenter registry of infliximab use in childhood uveitis
Systemic lupus erythematosus tumor registry
Observational registry of adalimumab in children with juvenile idiopathic arthritis
Clinical trial of rilonacept treatment in systemic juvenile idiopathic arthritis
Developing disease activity measures in linear scleroderma
NIH Patient Reported Outcomes Measurement Information System (PROMIS) Pediatric item bank development to enhance health related quality of life reporting
Observational registry of childhood vasculitis
Enhanced drug safety and surveillance reporting project
Observational registry of celecoxib and NSAIDs in children with juvenile idiopathic arthritis

Translational Research

Nitric oxide metabolism in statin treated pediatric systemic lupus erythematosus
Microarray assessment in childhood lupus erythematosus
Endothelial progenitor cells in pediatric SLE and atherosclerosis