Division of Rheumatology

Clinical Trials

For information about clinical trials, please call:

Janet Wootton, R.N. 919-684-2575

Kelly Mieszkalski, M.A., C.C.R.C. 919-684-4709

Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE). Multicenter, NIH sponsored, randomized, double-blind, placebo-controlled Childhood Arthritis and Rheumatology Research Alliance (CARRA). More information at www.carragroup.org/content_dsp.do?pc=studies. Study based at Duke examining effects of atorvastatin (Lipitor) in reducing the progression of carotid IMT in childhood SLE. Key investigators: Laura Schanberg MD. Collaborators: Christy Sandborg MD (Stanford), Duke Clinical Research Institute. More information at www.clinicaltrials.gov/ct/show/NCT00065806?order=2

Rituximab in Myositis. Multicenter, NIH sponsored trial examining the effectiveness of rituximab in treating refractory myositis in children and adults. Sponsor: University of Pittsburgh/NIH. PI: Egla Rabinovich, M.D.

Adaptations & Cognitive Behavioral Intervention in Female Adolescents with Lupus. NIH sponsored multicenter trial based at Medical University of South Carolina examining effectiveness of a coping and education computer based program on health outcome in female adolescents wtih lupus. Key investigators: Melanie Bonner Ph.D. Kelly Anthony Ph.D, Laura Schanberg M.D., Ron Brown Ph.D, Rick Silver M.D. (MUSC).