pediatrics.duke.edu  
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Division of Pulmonary and Sleep Medicine

Asthma Clinical Research Center


Welcome

The American Lung Association (ALA) supports an Asthma Clinical Research Center (ACRC) at Duke University Medical Center--the ALA-ACRC. The Center involves three divisions at Duke:

The Principal Investigator is:

John Sundy, MD, PhD
Department of Medicine
Division of Pulmonary, Allergy and Critical Care
Duke University Medical Center
Box 3278
Durham, NC 27710

Tel: 919-668-2169
Fax: 919-681-8298
 
 
The national office of the American Lung Association and its affiliated Lung Associations around the country, including the American Lung Association of North Carolina, support a network of twenty Asthma Clinical Research Centers. This initiative brings together a nationwide corps of scientists and medical researchers with clinical expertise in asthma with a goal of improving clinical care for asthma.

About the ACRC

The ALA-ACRC develops and performs clinical research studies of asthma patients including a broad range of age groups with appropriate gender and minority representation. Duke University Medical Center is the ACRC for North Carolina. The research conducted at the Center will potentially lead to major advances in the understanding and prevention of asthma, which will contribute many times over to alleviating suffering and reducing health care costs.
 
The Asthma Research Initiative is the American Lung Association's nationwide effort to improve the treatment of asthma and, ultimately, to find a cure. The Asthma Research Initiative is sponsored by the national ALA with contributions from local American Lung Association (ALA) offices throughout the country, including the American Lung Association of North Carolina. The ALA-ACRC opened in July 1999 to conduct clinical research trials on large numbers of asthma patients.
 
The Duke Asthma Clinical Research Center is dedicated to quality research for the treatment of asthma and allergy related diseases. The ACRC is staffed by Pediatric and Internal Medicine Physicians, Nurses, and Respiratory Therapists. Clinical trials are conducted in both children and adults.

"Breathing less is not an option"

We hope to help sustain the life and breath of asthma patients, but we depend on the help of people with asthma to enroll in our studies to be part of the cure.

Current Clinical Trials

The Duke Asthma Clinical Research Center is seeking participants for asthma research studies. Studies are sponsored by the American Lung Association, often in collaboration with the NIH and pharmaceutical companies. The following studies are currently open for enrollment.


Study of Acid Reflux in Children with Asthma (SARCA Study)

What is the purpose of this study?
Physicians at the Duke Asthma Clinical Research Center (ACRC) are studying acid reflux (GER) and asthma. Asthma may be hard to control because of GER. Children with asthma may be eligible for the study even without symptoms of acid reflux.
 
What does this study involve?
The study involves nine visits over a six month time period. Individuals 6 to 17 years old may be eligible to participate in this study.

Subjects receive:

  • Testing for gastroesophageal reflux (GER)
  • Study medication
  • Lung function testing
  • Compensation for participation

For further infomation, please call Catherine Foss, RRT, CCRC or Denise Jaggers, RN at 919-684-0191.

If you are interested in participating in this study, email DukeACRC@mc.duke.edu and provide your contact information (email and/or phone number). A research coordinator will follow up with you by phone.

 
(Ref # e-0739)


Methacholine Broncoprovocation Influence of High Potency Corticosteroids in Asthma (MeCIS)

What is the purpose of this study?
The American Lung Association and physicians at the Duke Asthma Clinical Research Center are interested in learning more about the influence of high potency corticosteroids in asthma.
 
What does this study involve for asthma participants?
The study involves five visits over a three month time period for asthma participants. Participants with asthma must be diagnosed by a physician and under good control (few or no asthma symptoms during the last four weeks).

Subjects may receive:

  • Allergy skin testing
  • Lung function testing
  • Study medication
  • Compensation for participation
     
What does this study involve for healthy participants?
The study involves one visit for healthy/non-asthmatic participants. Eligible participants must have no history of asthma or allergies and be a nonsmoker.

Subjects may receive:

  • Allergy skin testing
  • Lung function testing
  • Compensation for participation
     
For further infomation, please call John Sundy, MD, Cathy Foss, RRT, CCRC, or Denise Jaggers, RN at 919-684-0191.

If you are interested in participating in this study, email DukeACRC@mc.duke.edu and provide your contact information (email and/or phone number). A research coordinator will follow up with you by phone.
 
(Ref #e-9088)


 

 

 
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Contact Information
Division Offices 
350 Hanes House
DUMC Box 102360
Durham, NC 27710
919-684-3364
919-684-2292 fax
Duke Children’s Hospital & Health Center
New and Return Appointments:
919-668-4000 or 919-684-3364
Nurse Help Line: 919-684-2279
Prescription Line: 919-684-2086 
 
Duke Asthma, Allergy and Airways Disorder Center
New and Return Appointments:
919-668-4000 or 919-684-3364

Duke Children's Consultative Services of Raleigh
New and Return Appointments:
919-668-4000 or 919-862-5750
 
Urgent Calls During Business Hours
919-684-3364
 
Pediatric Pulmonologist On-Call
Evenings/Weekends/Holidays:
919-684-8111, ask for Pager #7315

Duke Asthma Clinical Research Center
For information about current clinical trials:
919-684-0191
Links
 
 

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