pediatrics.duke.edu  
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Division of Infectious Diseases

Research 

Overview

Faculty and fellows of the Division of Pediatric Infectious Diseases are engaged in a wide range of clinical, translational and basic investigation related to pediatric infectious diseases.  
 
The research being conducted in the Division of Pediatric Infectious Diseases is broadly based.  These areas of research include viral, fungal and bacterial pathogenesis; prevention and treatment of pediatric HIV-infection; prevention and treatment of infection in neonates and other immunocompromised hosts; and treatment of infectious diseases in the international setting.

Research Faculty

Name 
Areas of Special Interest 
Treatment of pediatric HIV, prevention of perinatal HIV transmission, and HIV vaccine studies 
Multicenter pediatric anti-infective trials, neonatal infections 
Safety, efficacy and pharmacokinetics of antimicrobials in infants
Pediatric vaccine trials 
General infectious diseases, medical education 
 
Basic pathogenesis of hepatitis C, clinical outcomes of hepatitis C infection 
Treatment of HIV infection in children, medical  education 
Clinical research in treatment of pediatric HIV infection 
HIV and Tb vaccine design and development 
Molecular and cellular determinants of uropathogenic E. coli infection 
Haemophilus influenzae pathogenesis and vaccine development 
Clinical and basic research in invasive fungal infections, with primary interest in Aspergillus pathogenesis 
Vaccine research in the Pediatric Primary Care Division, pediatric travel, international adoption 
Samuel L. Katz, MD, emeritus 
Pediatric vaccines, vaccine delivery in low resource settings
Treatment of HIV-infected children, prevention of mother-to- child HIV transmission in resource limited settings 
 

Clinical Research

  • Evaluation of mother-to-child transmission of HIV
  • Treatment of HIV and co-infections
  • Evaluation of HIV vaccines in domestic as well as international settings 
  • Development and testing of candidate Tb and HIV vaccines
  • Virulence factors in Hepatitis C

Basic Research

Bacterial Pathogenesis
  • Haemophilus influenzae pathogenesis and vaccine development
  • Molecular and cellular determinants of uropathogenic E. coli infection

    Fungal Pathogenesis
    • Evaluation of the pathogenic mechanisms of Aspergillus infection.



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    Contact Information
    Division offices 
    T915 Children's Health Center
    Duke University Medical Center, Box 3499
    Durham, NC 27710
    919-684-6335
    919-668-4859 fax 
    Other numbers 
    Pediatrician on call 24 hours a day, 7 days a week:
    919-970-7420
    919-970-7423 alternate
    Links
    Katz-Wilfert Update at katzwilfert.pediatrics.duke.edu
     
    Pediatric Fungal Network at pfn.pediatrics.duke.edu
     
    Center for HIV-AIDS Vaccine Immunology at chavi.org
     
    Duke Division of Infectious Diseases and International Health at
    Pediatrics Infectious Diseases Society at www.pids.org  Infectious Diseases Society of America at www.idsociety.org

    National Pediatric AIDS Network at www.npan.org

    Women, Children, and HIV at www.womenchildrenhiv.org 
     
    International Maternal Pediatric Adolescent AIDS Clinical Trials Group
     
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