pediatrics.duke.edu  
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Division of Pediatric Cardiology

Research Overview

The faculty and fellows in the Division of Pediatric Cardiology have a wide variety of research interests in clinical, translational, and basic investigation related to childhood heart disease.

Faculty & Staff

Name 
Areas of Interest 
Medical education, cardiac catheterization
Fetal cardiology, cardiac imaging (echo, MRI)
Cardiac imaging (echo), quality improvement
Cardiac imaging (echo, MRI)
Arrhythmias, heart failure/transplantation
Cardiac devices, percutaneious interventions
Arrhythmias
Cardiovascular defects, especially those related to the arterial pole
Arrhythmias, syncope, autonomic dysfunction
Etiology and pathogenesis of congenital heart defects
Hypertension, thrombosis, heart failure clinical trials
Fetal cardiology, cardiac imaging (echo)
Fetal cardiology, cardiac imaging (echo)
Cardiac outcomes, health services research
Cardiac devices, percutaneious interventions
Cardiac genetics (Marfan syndrome, muscular dystrophies)

Clinical Research

Participation in trials conducted by the Pediatric Heart Network funded by the National Heart, Lung, and Blood Institute:
  • Hypoplastic Left Heart Syndrome
  • Kawasaki Disease
  • Cardiomyopathy
  • Marfan Syndrome
  • Atrioventricular Canal
  • Fontan

Other clinical trials in:
  • RSV vaccines
  • Hypertension
  • Heart failure
  • Thrombosis
  • Supraventricular tachycardia

Cardiac imaging:
  • 3D echo
  • Torsion
  • Strain-rate
  • MRI

Assessment of various devices to repair congenital cardiac lesions
  • Atrial septal defect/patent foramen ovale (device occluder)
  • Ventricularr septal defect (device occluder)
  • Coarctation of the aorta (stents)
  • Cutting balloon for relief of pulmonary artery obstruction
  • Percutaneous pulmonary valve

Outcomes assessment following:
  • Congenital heart surgery
  • Radiofrequency ablation
  • Heart transplantation
  • Implantable Cardioverter Defibrillator (ICD)

Translational/Basic Research

  • Stability of Cardiac Response to Pacing
    Study of the complex and nonlinear response of the cardiac electrical system to rapid pacing in order to understand and potentially prevent the transition from a stable to an unstable cardiac rhythm utilizing multifaceted experimental and theoretical methods to drive the development of computer models.

Fellow Research

Current and recent fellows have worked on the following projects:
  • Glycogen Storage Disease/Pompe Disease clinical trials
  • Outcomes of children undergoing surgery in the Society of Thoracic Surgery Congenital Heart Database
  • Pediatric hypertension clinical trials
  • Endothelial signaling pathways that regulate angiogenesis and vascular remodeling
  • Doppler assessment of mesenteric artery flow in Sano vs. BT shunts in HLHS
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Contact Information
Division offices 
7506 Hospital North
DUMC Box 3090
Durham, NC 27710
919-681-2916
919-681-8927 fax
Other numbers 
Appointments: 919-668-4000
 
Urgent calls during business hours: 919-681-2916
 
Pediatric cardiologist on call evenings/weekends/holidays:  919-684-8111
(Ask operator to page Pediatric Cardiologist on call.)
Links
American College of Cardiology at www.acc.org

American Heart Association at my.americanheart.org
 
Cardiosource at www.cardiosource.com
 
Clinical Cardiology www.clinicalcardiology.org
 
Congential Heart Disease Information and Resources at chin.org
 
Down Syndrome Home Page at www.nas.com/downsyn
 
Heart Surgery Forum at www.hsforum.com
 
Hypertrophic Cardiomyopathy Association at www.4hcm.org
 
Sudden Arrhythmic Death Syndrome (SADS) Foundation at sads.org
 
PediHeart at www.pediheart.org
 
Velo-Cardio-Facial Syndrome Education Foundation at www.vcfsef.org
 
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