Salim F. Idriss, MD, PhD



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Associate Professor of Pediatrics
Department / Division:
Pediatrics / Pediatrics-Cardiology
DUMC 3090
Durham, NC 27710

23 Sunnybrook Road, Suite 200
Raleigh, NC 27610
Appointment Telephone:
Office Telephone:
919-862-1269, 919-681-6772
919-862-5355, 919-668-6122
  • MD, Duke University School of Medicine, 1996
  • Pediatrics, Rainbow Babies & Children's Hospital, Case Western Reserve University (Ohio), 1996-1999
  • Pediatric Cardiology and Electrophysiology, Duke University Medical Center, 1999-2003
Other Training:
  • PhD, Pathology (Cardiac Electrophysiology), Duke University Medical Center, 1995
Clinical Interests:
Cardiac arrhythmias, syncope, and sudden death; cardiac pacing and defibrillation; electrophysiologic studies and ablation of cardiac arrhythmias; evaluation and treatment of congenital and acquired heart disease in infants, children, and adolescents
Research Interests:
I am primarily interested in the effects of age and development on cardiac electrical stability. The electrical properties of the myocardium continue to develop and mature after birth. These changes may affect susceptibility to malignant arrhythmias at different ages. I am investigating these changes in collaboration with faculty in Biomedical Engineering, Mathematics, and Physics.
I have a second interest in real-time three-dimensional echocardiography for visualization and guidance of interventional electrophysiologic procedures.
Representative Publications:
  • Williams, RV; Travison, T; Kaltman, JR; Cecchin, F; Colan, SD; Idriss, SF; Lu, M; Margossian, R; Reed, JH; Silver, ES; Stephenson, EA; Vetter, VL; Pediatric Heart Network Investigators. Comparison of Fontan survivors with and without pacemakers: a report from the Pediatric Heart Network Fontan Cross-Sectional Study. Congenital Heart Disease. 2013;8:32-39.  Abstract
  • Idriss, S; Kanter, RJ. Maximum voltage-guided catheter ablation of typical atrial flutter: making a good procedure even better?. Journal of Cardiovascular Electrophysiology. 2012;23:486-488.  Abstract
  • Doshi, AN; Idriss, SF. Effect of resistive barrier location on the relationship between T-wave alternans and cellular repolarization alternans: a 1-D modeling study. Journal of Electrocardiology. 2010;43:566-571.  Abstract
  • Kanter, RJ; Idriss, S; Zuelgaray, JG. Paroxysmal high-grade atrioventricular block and syncope in a previously healthy child: what is the mechanism?. Journal of Cardiovascular Electrophysiology. 2010;21:585-587.  Abstract
  • Stephenson, EA; Lu, M; Berul, CI; Etheridge, SP; Idriss, SF; Margossian, R; Reed, JH; Prakash, A; Sleeper, LA; Vetter, VL; Blaufox, AD; Pediatric Heart Network Investigators. Arrhythmias in a contemporary fontan cohort: prevalence and clinical associations in a multicenter cross-sectional study. Journal of the American College of Cardiology. 2010;56:890-896.  Abstract
  • Doshi, AN; Idriss, SF. Relationship between extracellular T-wave height, T-wave alternans amplitude, and tissue action potential alternans: a 1-dimensional computer modeling study. Journal of Electrocardiology. 2009;42:549-554.  Abstract
  • Hakacova, N; Robinson, AM; Maynard, C; Wagner, GS; Idriss, SF. Determination of the mitral papillary muscle positions by the septal-to-free wall arc ratio method. Clinical Physiology and Functional Imaging. 2009;29:181-186.  Abstract
  • Hakacova, N; Wagner, GS; Idriss, SF. Electroanatomic relationships in patients with primum atrioventricular septal defect. JACC: Cardiovascular Imaging. 2009;2:1357-1365.  Abstract
  • Ratnasamy, C; Idriss, SF; Carboni, MP; Kanter, RJ. Arrhythmias in children having a single left superior vena cava and minimal structural heart disease. Journal of Cardiovascular Electrophysiology. 2009;20:182-186.  Abstract
  • Ring, CL; Idriss, SF; Neu, WK. Variability of action potential duration in pharmacologically induced long QT syndrome type 1. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2009;2009:4520-4522.  Abstract
  • Fronheiser, MP; Idriss, SF; Wolf, PD; Smith, SW. Vibrating interventional device detection using real-time 3-D color Doppler. IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control. 2008;55:1355-1362.  Abstract
  • Idriss, SF; Bell, JA. Cardiac repolarization instability during normal postnatal development. Journal of Electrocardiology. 2008;41:474-479.  Abstract
  • Bell, J; Rouze, N; Krassowska, W; Idriss, S. The Electrocardiogram Restitution Portrait Quantifying Dynamical Electrical Instability in Young Myocardium. Computers in cardiology. 2007;34:789-792.  Abstract
  • Pitruzzello, AM; Krassowska, W; Idriss, SF. Spatial heterogeneity of the restitution portrait in rabbit epicardium. American journal of physiology. Heart and circulatory physiology. 2007;292:H1568-H1578.  Abstract
  • Pua, EC; Idriss, SF; Wolf, PD; Smith, SW. Real-time three-dimensional transesophageal echocardiography for guiding interventional electrophysiology: feasibility study. Ultrasonic Imaging. 2007;29:182-194.  Abstract
  • Ansong, AK; Li, JS; Nozik-Grayck, E; Ing, R; Kravitz, RM; Idriss, SF; Kanter, RJ; Rice, H; Chen, YT; Kishnani, PS. Electrocardiographic response to enzyme replacement therapy for Pompe disease. Genetics in Medicine. 2006;8:297-301.  Abstract
  • Fronheiser, MP; Light, ED; Idriss, SF; Wolf, PD; Smith, SW. Real-time, 3-D ultrasound with multiple transducer arrays. IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control. 2006;53:100-105.  Abstract
  • Horenstein, MS; Idriss, SF; Hamilton, RM; Kanter, RJ; Webster, PA; Karpawich, PP. Efficacy of signal-averaged electrocardiography in the young orthotopic heart transplant patient to detect allograft rejection. Pediatric Cardiology. 2006;27:589-593.  Abstract
  • Idriss, SF; Pitruzzello, AM. A low-cost high-efficiency fiber-optic coupler for recording action potentials within the myocardial wall. IEEE Transactions on Biomedical Engineering. 2006;53:1708-1711.  Abstract
  • Light, ED; Idriss, SF; Sullivan, KF; Wolf, PD; Smith, SW. Real-time 3D laparoscopic ultrasonography. Ultrasonic Imaging. 2005;27:129-144.  Abstract
  • Pitruzzello, AM; Krassowska, W; Lam, AJ; Idriss, SF. A MULTICHANNEL FIBER-OPTIC MAPPING SYSTEM FOR INTRAMURAL RECORDING OF CARDIAC ACTION POTENTIALS. Ifmbe Proceedings. 2005;11:nihms8476.  Abstract
  • Fronheiser, MP; Wolf, PD; Idriss, SF; Nelson, RC; Lee, W; Smith, SW. Real-time 3D color flow Doppler for guidance of vibrating interventional devices. Ultrasonic Imaging. 2004;26:173-184.  Abstract
  • Goodman, AM; Clyde, MA; Burdick, DS; Idriss, SF; Wolf, PD. Minimum energy single-shock internal atrial defibrillation in sheep. Journal of Interventional Cardiac Electrophysiology. 2004;10:131-138.  Abstract
  • Idriss, SF; Wolf, PD. Transmural action potential repolarization heterogeneity develops postnatally in the rabbit. Journal of Cardiovascular Electrophysiology. 2004;15:795-801.  Abstract
  • Kalb, SS; Dobrovolny, HM; Tolkacheva, EG; Idriss, SF; Krassowska, W; Gauthier, DJ. The restitution portrait: a new method for investigating rate-dependent restitution. Journal of Cardiovascular Electrophysiology. 2004;15:698-709.  Abstract
  • Lee, W; Idriss, SF; Wolf, PD; Smith, SW. A miniaturized catheter 2-D array for real-time, 3-D intracardiac echocardiography. IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control. 2004;51:1334-1346.  Abstract
  • Pua, EC; Idriss, SF; Wolf, PD; Smith, SW. Real-time 3D transesophageal echocardiography. Ultrasonic Imaging. 2004;26:217-232.  Abstract
  • Smith, SW; Chu, K; Idriss, SF; Ivancevich, NM; Light, ED; Wolf, PD. Feasibility study: real-time 3-D ultrasound imaging of the brain. Ultrasound in Medicine & Biology. 2004;30:1365-1371.  Abstract
  • Lee, W; Idriss, SF; Wolf, PD; Smith, SW. Dual lumen transducer probes for real-time 3-D interventional cardiac ultrasound. Ultrasound in Medicine & Biology. 2003;29:1297-1304.  Abstract
  • Idriss, SF; Van Hare, GF; Fink, D; Rosenbaum, DS. Microvolt T wave alternans inducibility in normal newborn puppies: effects of development. Journal of Cardiovascular Electrophysiology. 2002;13:593-598.  Abstract
  • Light, ED; Idriss, SF; Lee, W; Wolf, PD; Smith, SW. Feasibility study for real time three dimensional Doppler intracardiac echocardiography. Ultrasonic Imaging. 2002;24:36-46.  Abstract
  • Smith, SW; Light, ED; Idriss, SF; Wolf, PD. Feasibility study of real-time three-dimensional intracardiac echocardiography for guidance of interventional electrophysiology. Pacing and Clinical Electrophysiology. 2002;25:351-357.  Abstract
  • Light, ED; Idriss, SF; Wolf, PD; Smith, SW. Real-time three-dimensional intracardiac echocardiography. Ultrasound in Medicine & Biology. 2001;27:1177-1183.  Abstract
  • Idriss, SF; Wolf, PD; Smith, WM; Ideker, RE. Effect of pacing site on ventricular fibrillation initiation by shocks during the vulnerable period. The American journal of physiology. 1999;277:H2065-H2082.  Abstract
  • Callihan, RL; Idriss, SF; Dahl, RW; Wolf, PD; Smith, WM; Ideker, RE. Comparison of defibrillation probability of success curves for an endocardial lead configuration with and without an inactive epicardial patch. JACC - Journal of the American College of Cardiology. 1995;25:1373-1379.  Abstract
  • Fotuhi, PC; Ideker, RE; Idriss, SF; Callihan, RL; Walker, RG; Alt, EU. Influence of epicardial patches on defibrillation threshold with nonthoracotomy lead configurations. Circulation. 1995;92:3082-3088.  Abstract
  • Idriss, SF; Anstadt, MP; Anstadt, GL; Ideker, RE. The effect of cardiac compression on defibrillation efficacy and the upper limit of vulnerability. Journal of Cardiovascular Electrophysiology. 1995;6:368-378.  Abstract
  • Idriss, SF; Melnick, SB; Wolf, PD; Smith, WM; Ideker, RE. Predicting the potential gradient field in ventricular fibrillation from shocks delivered in paced rhythm. The American journal of physiology. 1995;268:H2336-H2344.  Abstract
  • Malkin, RA; Idriss, SF; Walker, RG; Ideker, RE. Effect of rapid pacing and T-wave scanning on the relation between the defibrillation and upper-limit-of-vulnerability dose-response curves. Circulation. 1995;92:1291-1299.  Abstract
  • Bayly, PV; Johnson, EE; Idriss, SF; Ideker, RE; Smith, WM. Efficient electrode spacing for examining spatial organization during ventricular fibrillation. IEEE Transactions on Biomedical Engineering. 1993;40:1060-1066.  Abstract