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Research
 

Research Faculty
 

Name
Areas of Special Interest
Ronald N. Goldberg, MD, Chief Perinatal asphyxia, use of stem cell/cord blood therapy for perinatal asphyxia.
Mechanisms by which oxidative stress disrupts postnatal lung development in premature newborns.
Margarita Bidegain, MD, MHS Palliative care.
Role of the macrophage in alveolar simplification as a feature of bronchopulmonary dysplasia.
C. Michael Cotten, MD, MHS Use of cord blood therapy for perinatal asphyxia, use of genomic studies to diagnose and guide neonatal therapy.
Erica Davis, PhD Functional interpretation of variation at the DNA level beyond the resolution of genetics arguments. Mapping pathogenic alleles back to disease phenotypes.
Use of medical informatics, computerized patient safety initiatives.
Ricki F. Goldstein, MD Neurodevelopmental follow-up of high-risk infants. 
Mary Hutson, PhD Cardiovascular defects, especially those related to the arterial pole.
Chay Kuo, MD, PhD Neurodevelopmental research of neural stem cells.
William Malcolm, MD Diagnosis and management of gastroesophageal reflux.
P. Brian Smith, MD, MHS Nosocomial infections, neonatal candidiasis, neonatal pharmacology.
David T. Tanaka, MD Health care economics.


Clinical Research

  • Problems of low birth weight infants, morbidity and mortality, perinatal asphyxia, ventilatory management, growth and development of high-risk infants, and the role of genomics in neonatal morbidity
  • Neurodevelopmental outcomes of high-risk infants.

Basic Research

  • Causes of birth defects that particularly affect the cardio-craniofacial field and left-right cardiac axis determination
  • Perinatal mechanisms of disrupted development and post-natal injury with special emphasis on lung, brain, and heart 

Translational Research

  • Neonatal pulmonary hypertension, pulmonary injury, and lung function

Health Care Economics Research

  • Medical economics, and biomedical engineering, specifically, in the areas of informatics, optics, virtual reality and microdigital fluidics.

The Jean and George Brumley Jr. Neonatal Perinatal Research Institute (NPRI)

The Jean and George Brumley Jr. Neonatal Perinatal Research Institute (NPRI) aims to provide a dedicated environment wherein investigators from different fields can participate in collaborative multidisciplinary research aimed at understanding the basis of key problems suffered by neonates. 

National Institute of Child Health and Human Development (NICHD) Neonatal Research Network

The Duke Division of Neonatology is a member of the National Institute of Child Health and Human Development (NICHD) Neonatal Research Network, a consortium of the leading neonatal intensive care units in the country that perform cutting-edge, collaborative clinical research.

Clinical Trials

In the Division of Neonatology, we continually seek to improve health care practices by conducting clinical research, which includes our membership with the NICHD. We have many ongoing clinical trials in our Intensive Care Nursery (ICN). The Neonatal-Perinatal Research Unit (NPRU) provides the professional infrastructure to complete these studies. The Operations Director of the NPRU is Kimberley Fisher, PhD. Dr. Fisher is assisted by five study coordinators as well as other support staff that contribute to the success of clinical trials. Michael Cotten, MD is the Medical Director for the NPRU and the Director of Clinical Research for the Neonatal-Perinatal Research Institute. Ricki Goldstein, MD is responsible for the developmental follow-up portion of our studies.

For more information about clinical trials in the Division, contact Kimberley Fisher, PhD, at 919.681.4913 or kimberley.fisher@duke.edu.